Explore topic-wise MCQs in Graduate Aptitude Test (GATE).

This section includes 46 Mcqs, each offering curated multiple-choice questions to sharpen your Graduate Aptitude Test (GATE) knowledge and support exam preparation. Choose a topic below to get started.

1.

What is the relationship between ∆G and ∆G‘°?

A. ∆G = ∆G‘° + RTln([products]/[reactants])
B. ∆G = ∆G‘° – RTln([products]/[reactants])
C. ∆G = ∆G‘° + RTln([reactants]/[products])
D. ∆G = ∆G‘° – RTln([reactants]/[products])
Answer» B. ∆G = ∆G‘° – RTln([products]/[reactants])
2.

If ∆G‘° of the reaction A → B is -40kJ/mol under standard conditions then the reaction

A. Will never reach equilibrium
B. Will not occur spontaneously
C. Will proceed at a rapid rate
D. Will proceed from left to right spontaneously
Answer» E.
3.

 The study of energy relationships and conversions in biological systems is called as

A. Biophysics
B. Biotechnology
C. Bioenergetics
D. Microbiology
Answer» D. Microbiology
4.

 Unfolding of regular secondary protein structure causes

A. Large decrease in the entropy of the protein
B. Little increase in the entropy of protein
C. No change in the entropy of the protein
D. Large increase in the entropy of the protein
Answer» E.
5.

 For a reaction if ∆G° is positive, then

A. The products will be favored
B. The reactants will be favored
C. The concentration of the reactants and products will be equal
D. All of the reactant will be converted to products
Answer» C. The concentration of the reactants and products will be equal
6.

 ∆G° is defined as the

A. Residual energy present in the reactants at equilibrium
B. Residual energy present in the products at equilibrium
C. Difference in the residual energy of reactants and products at equilibrium
D. Energy required in converting one mole of reactants to one mole of products
Answer» E.
7.

 Glycolysis converts

A. Glucose into pyruvate
B. Glucose into phosphoenolpyruvate
C. Fructose into pyruvate
D. Fructose into phosphoenolpyruvate
Answer» B. Glucose into phosphoenolpyruvate
8.

The product formed in the first substrate level phosphorylation in glycolysis is

A. Pyruvate
B. 3-phosphoglycerate
C. 1, 3-bisphosphoglycerate
D. 2-phosphoglycerate
Answer» C. 1, 3-bisphosphoglycerate
9.

High concentration of glucose 6-phosphate is inhibitory to

A. Hexokinase
B. Pyruvate kinase
C. Glucokinase
D. Phosphofructokinase-1
Answer» B. Pyruvate kinase
10.

 The substrate used in the last step of glycolysis is

A. Glyceraldehyde 3-phosphate
B. Pyruvate
C. Phosphoenolpyruvate
D. 1, 3-bisphosphoglycerate
Answer» D. 1, 3-bisphosphoglycerate
11.

 The first step in the payoff phase of glycolysis is

A. Reduction of 1, 3-bisphosphoglycerate to glyceraldehyde 3-phosphate
B. Oxidation of glyceraldehyde 3-phosphate to 1, 3-bisphosphoglycerate
C. Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate
D. Irreversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate
Answer» C. Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate
12.

Dihydroxyacetone phosphate is rapidly and reversibly converted to

A. Glyceraldehyde 3-phosphate
B. 1, 3-bis-phosphoglycerate
C. Fructose 1, 6-bisphosphate
D. Fructose 6-phosphate
Answer» B. 1, 3-bis-phosphoglycerate
13.

 Cleavage of Fructose 1, 6-biophosphate yields

A. Two aldoses
B. Two ketoses
C. An aldose and a ketose
D. Only a ketose
Answer» D. Only a ketose
14.

 Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased?

A. Hexokinase
B. Pyruvate kinase
C. Glucokinase
D. Phosphofructokinase-1
Answer» E.
15.

The general term used for the anaerobic degradation of glucose to obtain energy is

A. Anabolism
B. Oxidation
C. Oxidation
D. Metabolism
Answer» D. Metabolism
16.

Which of the following enzyme catalyzes the first step of glycolysis?

A. Hexokinase
B. Pyruvate kinase
C. Glucokinase
D. Phosphofructokinase-1
Answer» B. Pyruvate kinase
17.

 Which out of the following enzymes can utilize both NAD+ and NADP+ as a coenzyme?

A. Glutamate dehydrogenase
B. Alcohol dehydrogenase
C. Aldehyde dehydrogenase
D. Glycerol-3-P ddehydrogenase
Answer» B. Alcohol dehydrogenase
18.

Which of the following enzyme catalyzes the first step in the catabolism of ethanol?

A. Alcohol dehydrogenase
B. Lactate dehydrogenase
C. Glutamate dehydrogenase
D. Malate dehydrogenase
Answer» B. Lactate dehydrogenase
19.

Gain of electrons can be termed as

A. Metabolism
B. Anabolism
C. Oxidation
D. Reduction
Answer» E.
20.

Loss of electrons can be termed as

A. Metabolism
B. Anabolism
C. Oxidation
D. Reduction
Answer» D. Reduction
21.

Which of the following statements is incorrect about oxidase?

A. They catalyze reactions involving hydrogen peroxide
B. They catalyze reaction using O2 as a hydrogen acceptor
C. They catalyze reactions using niacin as coenzyme
D. They catalyze reactions of direct incorporation of O2 into the substrate
Answer» C. They catalyze reactions using niacin as coenzyme
22.

Which of the following enzyme catalyses the direct transfer and incorporation of O2 into a substrate molecule is

A. Reductase
B. Oxidase
C. Oxygenase
D. Peroxidase
Answer» D. Peroxidase
23.

Which one out of the following is not a NAD+ requiring enzyme?

A. Lactate dehydrogenase
B. Pyruvate dehydrogenase complex
C. Maltate dehydrogenase
D. Acyl co-A dehydrogenase
Answer» E.
24.

Which out of the following has the highest redox potential?

A. NAD
B. FMN
C. FAD
D. O2
Answer» E.
25.

 Which out of the following is not a flavoprotein?

A. Succinate dehydrogenase
B. Cytochrome c
C. Xanthine oxidase
D. NADH dehydrogenase-Qreductase
Answer» C. Xanthine oxidase
26.

 Which of the following statements about redox potential is false?

A. NADH/NAD+ redox pair has the least redox potential
B. Oxygen/H2O redox pair has the highest redox potential
C. The components of electron transport chain are organized in terms of their redox potential
D. The redox potential of a system is usually compared with the potential of the hydrogen electrode
Answer» B. Oxygen/H2O redox pair has the highest redox potential
27.

An example for chemical to electromagnetic energy conversion that occurs in living organisms

A. ATP-driven muscle contraction
B. ATP-dependent photon emission in fireflies
C. light-induced electron flow in chloroplasts
D. ATP-driven active transport across a membrane
Answer» C. light-induced electron flow in chloroplasts
28.

An example for chemical to osmotic energy conversion that occurs in living organisms

A. ATP-driven muscle contraction
B. ATP-dependent photon emission in fireflies
C. light-induced electron flow in chloroplasts
D. ATP-driven active transport across a membrane
Answer» E.
29.

Which of the following is false about acetyl-coA?

A. It is a thioester
B. It has a large, negative standard free energy of hydrolysis
C. It contains phosphorous atom in the position occupied by an oxygen atom in oxygen esters
D. It contains sulfur atom in the position occupied by an oxygen tom in oxygen esters
Answer» D. It contains sulfur atom in the position occupied by an oxygen tom in oxygen esters
30.

The phosphate groups used during glycolysis are

A. Organic
B. Inorganic
C. Neutral
D. None
Answer» C. Neutral
31.

 Water does a nucleophilic attack on phosphate monoester producing

A. Phosphorous chloride
B. Phosphorous sulfide
C. Inorganic phosphate
D. Organic phosphate
Answer» D. Organic phosphate
32.

 Phosphoryl groups are derivatives of

A. Phosphorous acid
B. Phosphoric acid
C. Acetic acid
D. Citric acid
Answer» C. Acetic acid
33.

An exergonic reaction

A. Proceeds spontaneously
B. Does not require activation energy
C. Releases energy
D. Requires energy
Answer» D. Requires energy
34.

An endergonic reaction

A. Proceeds spontaneously
B. Does not require activation energy
C. Releases energy
D. Requires energy
Answer» E.
35.

Which of the following statements is false about ATP hydrolysis?

A. It is highly exergonic
B. Activation energy is relatively high
C. ∆G‘°=-30.5kJ/mol
D. ∆G‘°=30.5kJ/mol
Answer» E.
36.

 Anabolism and catabolism are chemically linked in the form of

A. ADP
B. ATP
C. Phosphodiester linkage
D. ASP
Answer» C. Phosphodiester linkage
37.

Which of the following statements is false?

A. The reaction tends to go in the forward direction if ∆G is large and positive
B. The reaction tends to move in the backward direction if ∆G is large and negative
C. The system is at equilibrium if ∆G = 0
D. The reaction tends to move in the backward direction if ∆G is large and positive
Answer» E.
38.

What is the relationship between ∆G and ∆G‘°?

A. ∆G = ∆G‘° + RTln([products]/[reactants])
B. ∆G = ∆G‘° – RTln([products]/[reactants])
C. ∆G = ∆G‘° + RTln([reactants]/[products])
D. ∆G = ∆G‘° – RTln([reactants]/[products])
Answer» B. ∆G = ∆G‘° – RTln([products]/[reactants])
39.

 If ∆G‘° of the reaction A → B is -40kJ/mol under standard conditions then the reaction

A. Will never reach equilibrium
B. Will not occur spontaneously
C. Will proceed at a rapid rate
D. Will proceed from left to right spontaneously
Answer» E.
40.

What does first law of thermodynamics state?

A. Energy can neither be destroyed nor created
B. Energy cannot be 100 percent efficiently transformed from one type to another
C. All living organisms are composed of cells
D. Input of heat energy increases the rate of movement of atoms and molecules
Answer» B. Energy cannot be 100 percent efficiently transformed from one type to another
41.

The relationship between K‘eq and ∆G‘° is

A. ∆G‘° = RTlnK‘eq
B. ∆G‘° = -RTK‘eq
C. ∆G‘° = RK‘eq
D. ∆G‘° = -RK‘eq
Answer» C. ∆G‘° = RK‘eq
42.

The study of energy relationships and conversions in biological systems is called as

A. Biophysics
B. Biotechnology
C. Bioenergetics
D. Microbiology
Answer» D. Microbiology
43.

Unfolding of regular secondary protein structure causes

A. Large decrease in the entropy of the protein
B. Little increase in the entropy of protein
C. No change in the entropy of the protein
D. Large increase in the entropy of the protein
Answer» E.
44.

For a reaction if ∆G° is positive, then

A. The products will be favored
B. The reactants will be favored
C. The concentration of the reactants and products will be equal
D. All of the reactant will be converted to products
Answer» C. The concentration of the reactants and products will be equal
45.

∆G° is defined as the

A. Residual energy present in the reactants at equilibrium
B. Residual energy present in the products at equilibrium
C. Difference in the residual energy of reactants and products at equilibrium
D. Energy required in converting one mole of reactants to one mole of products
Answer» E.
46.

 If enthalpy change for a reaction is zero, then ∆G° equals to

A. -T∆S°
B. T∆S°
C. -∆H°
D. lnkeq
Answer» B. T∆S°