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This section includes 46 Mcqs, each offering curated multiple-choice questions to sharpen your Graduate Aptitude Test (GATE) knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
What is the relationship between ∆G and ∆G‘°? |
| A. | ∆G = ∆G‘° + RTln([products]/[reactants]) |
| B. | ∆G = ∆G‘° – RTln([products]/[reactants]) |
| C. | ∆G = ∆G‘° + RTln([reactants]/[products]) |
| D. | ∆G = ∆G‘° – RTln([reactants]/[products]) |
| Answer» B. ∆G = ∆G‘° – RTln([products]/[reactants]) | |
| 2. |
If ∆G‘° of the reaction A → B is -40kJ/mol under standard conditions then the reaction |
| A. | Will never reach equilibrium |
| B. | Will not occur spontaneously |
| C. | Will proceed at a rapid rate |
| D. | Will proceed from left to right spontaneously |
| Answer» E. | |
| 3. |
The study of energy relationships and conversions in biological systems is called as |
| A. | Biophysics |
| B. | Biotechnology |
| C. | Bioenergetics |
| D. | Microbiology |
| Answer» D. Microbiology | |
| 4. |
Unfolding of regular secondary protein structure causes |
| A. | Large decrease in the entropy of the protein |
| B. | Little increase in the entropy of protein |
| C. | No change in the entropy of the protein |
| D. | Large increase in the entropy of the protein |
| Answer» E. | |
| 5. |
For a reaction if ∆G° is positive, then |
| A. | The products will be favored |
| B. | The reactants will be favored |
| C. | The concentration of the reactants and products will be equal |
| D. | All of the reactant will be converted to products |
| Answer» C. The concentration of the reactants and products will be equal | |
| 6. |
∆G° is defined as the |
| A. | Residual energy present in the reactants at equilibrium |
| B. | Residual energy present in the products at equilibrium |
| C. | Difference in the residual energy of reactants and products at equilibrium |
| D. | Energy required in converting one mole of reactants to one mole of products |
| Answer» E. | |
| 7. |
Glycolysis converts |
| A. | Glucose into pyruvate |
| B. | Glucose into phosphoenolpyruvate |
| C. | Fructose into pyruvate |
| D. | Fructose into phosphoenolpyruvate |
| Answer» B. Glucose into phosphoenolpyruvate | |
| 8. |
The product formed in the first substrate level phosphorylation in glycolysis is |
| A. | Pyruvate |
| B. | 3-phosphoglycerate |
| C. | 1, 3-bisphosphoglycerate |
| D. | 2-phosphoglycerate |
| Answer» C. 1, 3-bisphosphoglycerate | |
| 9. |
High concentration of glucose 6-phosphate is inhibitory to |
| A. | Hexokinase |
| B. | Pyruvate kinase |
| C. | Glucokinase |
| D. | Phosphofructokinase-1 |
| Answer» B. Pyruvate kinase | |
| 10. |
The substrate used in the last step of glycolysis is |
| A. | Glyceraldehyde 3-phosphate |
| B. | Pyruvate |
| C. | Phosphoenolpyruvate |
| D. | 1, 3-bisphosphoglycerate |
| Answer» D. 1, 3-bisphosphoglycerate | |
| 11. |
The first step in the payoff phase of glycolysis is |
| A. | Reduction of 1, 3-bisphosphoglycerate to glyceraldehyde 3-phosphate |
| B. | Oxidation of glyceraldehyde 3-phosphate to 1, 3-bisphosphoglycerate |
| C. | Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate |
| D. | Irreversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate |
| Answer» C. Reversible conversion of dihydroxyacetone phosphate to glyceraldehyde 3-phosphate | |
| 12. |
Dihydroxyacetone phosphate is rapidly and reversibly converted to |
| A. | Glyceraldehyde 3-phosphate |
| B. | 1, 3-bis-phosphoglycerate |
| C. | Fructose 1, 6-bisphosphate |
| D. | Fructose 6-phosphate |
| Answer» B. 1, 3-bis-phosphoglycerate | |
| 13. |
Cleavage of Fructose 1, 6-biophosphate yields |
| A. | Two aldoses |
| B. | Two ketoses |
| C. | An aldose and a ketose |
| D. | Only a ketose |
| Answer» D. Only a ketose | |
| 14. |
Whenever the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased? |
| A. | Hexokinase |
| B. | Pyruvate kinase |
| C. | Glucokinase |
| D. | Phosphofructokinase-1 |
| Answer» E. | |
| 15. |
The general term used for the anaerobic degradation of glucose to obtain energy is |
| A. | Anabolism |
| B. | Oxidation |
| C. | Oxidation |
| D. | Metabolism |
| Answer» D. Metabolism | |
| 16. |
Which of the following enzyme catalyzes the first step of glycolysis? |
| A. | Hexokinase |
| B. | Pyruvate kinase |
| C. | Glucokinase |
| D. | Phosphofructokinase-1 |
| Answer» B. Pyruvate kinase | |
| 17. |
Which out of the following enzymes can utilize both NAD+ and NADP+ as a coenzyme? |
| A. | Glutamate dehydrogenase |
| B. | Alcohol dehydrogenase |
| C. | Aldehyde dehydrogenase |
| D. | Glycerol-3-P ddehydrogenase |
| Answer» B. Alcohol dehydrogenase | |
| 18. |
Which of the following enzyme catalyzes the first step in the catabolism of ethanol? |
| A. | Alcohol dehydrogenase |
| B. | Lactate dehydrogenase |
| C. | Glutamate dehydrogenase |
| D. | Malate dehydrogenase |
| Answer» B. Lactate dehydrogenase | |
| 19. |
Gain of electrons can be termed as |
| A. | Metabolism |
| B. | Anabolism |
| C. | Oxidation |
| D. | Reduction |
| Answer» E. | |
| 20. |
Loss of electrons can be termed as |
| A. | Metabolism |
| B. | Anabolism |
| C. | Oxidation |
| D. | Reduction |
| Answer» D. Reduction | |
| 21. |
Which of the following statements is incorrect about oxidase? |
| A. | They catalyze reactions involving hydrogen peroxide |
| B. | They catalyze reaction using O2 as a hydrogen acceptor |
| C. | They catalyze reactions using niacin as coenzyme |
| D. | They catalyze reactions of direct incorporation of O2 into the substrate |
| Answer» C. They catalyze reactions using niacin as coenzyme | |
| 22. |
Which of the following enzyme catalyses the direct transfer and incorporation of O2 into a substrate molecule is |
| A. | Reductase |
| B. | Oxidase |
| C. | Oxygenase |
| D. | Peroxidase |
| Answer» D. Peroxidase | |
| 23. |
Which one out of the following is not a NAD+ requiring enzyme? |
| A. | Lactate dehydrogenase |
| B. | Pyruvate dehydrogenase complex |
| C. | Maltate dehydrogenase |
| D. | Acyl co-A dehydrogenase |
| Answer» E. | |
| 24. |
Which out of the following has the highest redox potential? |
| A. | NAD |
| B. | FMN |
| C. | FAD |
| D. | O2 |
| Answer» E. | |
| 25. |
Which out of the following is not a flavoprotein? |
| A. | Succinate dehydrogenase |
| B. | Cytochrome c |
| C. | Xanthine oxidase |
| D. | NADH dehydrogenase-Qreductase |
| Answer» C. Xanthine oxidase | |
| 26. |
Which of the following statements about redox potential is false? |
| A. | NADH/NAD+ redox pair has the least redox potential |
| B. | Oxygen/H2O redox pair has the highest redox potential |
| C. | The components of electron transport chain are organized in terms of their redox potential |
| D. | The redox potential of a system is usually compared with the potential of the hydrogen electrode |
| Answer» B. Oxygen/H2O redox pair has the highest redox potential | |
| 27. |
An example for chemical to electromagnetic energy conversion that occurs in living organisms |
| A. | ATP-driven muscle contraction |
| B. | ATP-dependent photon emission in fireflies |
| C. | light-induced electron flow in chloroplasts |
| D. | ATP-driven active transport across a membrane |
| Answer» C. light-induced electron flow in chloroplasts | |
| 28. |
An example for chemical to osmotic energy conversion that occurs in living organisms |
| A. | ATP-driven muscle contraction |
| B. | ATP-dependent photon emission in fireflies |
| C. | light-induced electron flow in chloroplasts |
| D. | ATP-driven active transport across a membrane |
| Answer» E. | |
| 29. |
Which of the following is false about acetyl-coA? |
| A. | It is a thioester |
| B. | It has a large, negative standard free energy of hydrolysis |
| C. | It contains phosphorous atom in the position occupied by an oxygen atom in oxygen esters |
| D. | It contains sulfur atom in the position occupied by an oxygen tom in oxygen esters |
| Answer» D. It contains sulfur atom in the position occupied by an oxygen tom in oxygen esters | |
| 30. |
The phosphate groups used during glycolysis are |
| A. | Organic |
| B. | Inorganic |
| C. | Neutral |
| D. | None |
| Answer» C. Neutral | |
| 31. |
Water does a nucleophilic attack on phosphate monoester producing |
| A. | Phosphorous chloride |
| B. | Phosphorous sulfide |
| C. | Inorganic phosphate |
| D. | Organic phosphate |
| Answer» D. Organic phosphate | |
| 32. |
Phosphoryl groups are derivatives of |
| A. | Phosphorous acid |
| B. | Phosphoric acid |
| C. | Acetic acid |
| D. | Citric acid |
| Answer» C. Acetic acid | |
| 33. |
An exergonic reaction |
| A. | Proceeds spontaneously |
| B. | Does not require activation energy |
| C. | Releases energy |
| D. | Requires energy |
| Answer» D. Requires energy | |
| 34. |
An endergonic reaction |
| A. | Proceeds spontaneously |
| B. | Does not require activation energy |
| C. | Releases energy |
| D. | Requires energy |
| Answer» E. | |
| 35. |
Which of the following statements is false about ATP hydrolysis? |
| A. | It is highly exergonic |
| B. | Activation energy is relatively high |
| C. | ∆G‘°=-30.5kJ/mol |
| D. | ∆G‘°=30.5kJ/mol |
| Answer» E. | |
| 36. |
Anabolism and catabolism are chemically linked in the form of |
| A. | ADP |
| B. | ATP |
| C. | Phosphodiester linkage |
| D. | ASP |
| Answer» C. Phosphodiester linkage | |
| 37. |
Which of the following statements is false? |
| A. | The reaction tends to go in the forward direction if ∆G is large and positive |
| B. | The reaction tends to move in the backward direction if ∆G is large and negative |
| C. | The system is at equilibrium if ∆G = 0 |
| D. | The reaction tends to move in the backward direction if ∆G is large and positive |
| Answer» E. | |
| 38. |
What is the relationship between ∆G and ∆G‘°? |
| A. | ∆G = ∆G‘° + RTln([products]/[reactants]) |
| B. | ∆G = ∆G‘° – RTln([products]/[reactants]) |
| C. | ∆G = ∆G‘° + RTln([reactants]/[products]) |
| D. | ∆G = ∆G‘° – RTln([reactants]/[products]) |
| Answer» B. ∆G = ∆G‘° – RTln([products]/[reactants]) | |
| 39. |
If ∆G‘° of the reaction A → B is -40kJ/mol under standard conditions then the reaction |
| A. | Will never reach equilibrium |
| B. | Will not occur spontaneously |
| C. | Will proceed at a rapid rate |
| D. | Will proceed from left to right spontaneously |
| Answer» E. | |
| 40. |
What does first law of thermodynamics state? |
| A. | Energy can neither be destroyed nor created |
| B. | Energy cannot be 100 percent efficiently transformed from one type to another |
| C. | All living organisms are composed of cells |
| D. | Input of heat energy increases the rate of movement of atoms and molecules |
| Answer» B. Energy cannot be 100 percent efficiently transformed from one type to another | |
| 41. |
The relationship between K‘eq and ∆G‘° is |
| A. | ∆G‘° = RTlnK‘eq |
| B. | ∆G‘° = -RTK‘eq |
| C. | ∆G‘° = RK‘eq |
| D. | ∆G‘° = -RK‘eq |
| Answer» C. ∆G‘° = RK‘eq | |
| 42. |
The study of energy relationships and conversions in biological systems is called as |
| A. | Biophysics |
| B. | Biotechnology |
| C. | Bioenergetics |
| D. | Microbiology |
| Answer» D. Microbiology | |
| 43. |
Unfolding of regular secondary protein structure causes |
| A. | Large decrease in the entropy of the protein |
| B. | Little increase in the entropy of protein |
| C. | No change in the entropy of the protein |
| D. | Large increase in the entropy of the protein |
| Answer» E. | |
| 44. |
For a reaction if ∆G° is positive, then |
| A. | The products will be favored |
| B. | The reactants will be favored |
| C. | The concentration of the reactants and products will be equal |
| D. | All of the reactant will be converted to products |
| Answer» C. The concentration of the reactants and products will be equal | |
| 45. |
∆G° is defined as the |
| A. | Residual energy present in the reactants at equilibrium |
| B. | Residual energy present in the products at equilibrium |
| C. | Difference in the residual energy of reactants and products at equilibrium |
| D. | Energy required in converting one mole of reactants to one mole of products |
| Answer» E. | |
| 46. |
If enthalpy change for a reaction is zero, then ∆G° equals to |
| A. | -T∆S° |
| B. | T∆S° |
| C. | -∆H° |
| D. | lnkeq |
| Answer» B. T∆S° | |