MCQOPTIONS
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MCQOPTIONS
This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Biotechnology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
How to prevent hepatic first-pass metabolism for corticosteroids? |
| A. | Providing intravenously |
| B. | Providing orally |
| C. | Form esters and ether products |
| D. | By enhancing lipophilicity |
| Answer» D. By enhancing lipophilicity | |
| 2. |
Which of the following will not be a limitation for prodrug design? |
| A. | Formation of toxic product |
| B. | An inert carrier can be cleaved off forming toxic product |
| C. | Product cleaving off before reaching the target site |
| D. | The cleaving of the carrier is also site-specific |
| Answer» C. Product cleaving off before reaching the target site | |
| 3. |
Which of the following is not a disadvantage of site-specific drug delivery? |
| A. | May lead to toxic effects on other non-target tissues |
| B. | May get diluted |
| C. | Less distribution time |
| D. | No penetrable to the target tissue |
| Answer» E. | |
| 4. |
Why lipophilic drugs are absorbed easily? |
| A. | Less hydrolysed |
| B. | Favours passive diffusion |
| C. | Dissolution rate high |
| D. | Can easily merge with the cell membrane |
| Answer» D. Can easily merge with the cell membrane | |
| 5. |
Why carbenicillin cannot be given orally? |
| A. | Tastes bad |
| B. | Bad odour |
| C. | Degraded by saliva |
| D. | Hydrolysed easily |
| Answer» C. Degraded by saliva | |
| 6. |
Which one of these is the best way to preserve drugs for intravenous use? |
| A. | Lyophilisation |
| B. | Drying |
| C. | Freezing |
| D. | In solution form |
| Answer» E. | |
| 7. |
Which of the following reduces the pain of injection? |
| A. | If the drug precipitates |
| B. | If the drug penetrates to the surrounding areas |
| C. | If the solution is strongly acidic |
| D. | More water-soluble drug |
| Answer» B. If the drug penetrates to the surrounding areas | |
| 8. |
No drug cause damage to the gastric mucosa. |
| A. | True |
| B. | False |
| Answer» C. | |
| 9. |
Which one of the following will be an example of changing the physical form of the drug to get a prodrug? |
| A. | Ethyl mercaptan to 1,3-Diesters |
| B. | Trichloroethanol to p-Acetamidobenzene ester |
| C. | Ethyl mercaptan to phthalate esters |
| D. | Chloramphenicol to palmitate ester |
| Answer» B. Trichloroethanol to p-Acetamidobenzene ester | |
| 10. |
A liquid with high vapour pressure has a strong odour. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 11. |
How improvement of a drug in case of taste is done? |
| A. | Injecting the drug so no taste related problems |
| B. | Reducing the drug solubility in the saliva |
| C. | Lower affinity for the taste receptors and making the drug sweet |
| D. | Reducing drug solubility in saliva and lower affinity for taste receptors |
| Answer» E. | |
| 12. |
Which of the following will be the pharmacokinetic application of prodrugs? |
| A. | Improvement of taste |
| B. | Improvement of odour |
| C. | Site-specific drug delivery |
| D. | Reduction in GI irritation |
| Answer» D. Reduction in GI irritation | |
| 13. |
Which of the following will be a pharmaceutical application of prodrugs? |
| A. | Enhancement of bioavailability |
| B. | Reduction of toxicity |
| C. | Improvement of odour |
| D. | Site-specific drug delivery |
| Answer» D. Site-specific drug delivery | |