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This section includes 9 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
1. |
Both the subunits of heterodimers are involved in tRNA binding. |
A. | False |
B. | True |
Answer» C. | |
2. |
The tRNA makes contact with the synthetase at only a single specific position. |
A. | True |
B. | False |
Answer» C. | |
3. |
Tyrosine is activated at an amino group with ATP to form tyrosyl adenylate. |
A. | True |
B. | False |
Answer» C. | |
4. |
The charging of tRNATyr with tyrosine is a single-stage reaction. |
A. | True |
B. | False |
Answer» C. | |
5. |
Which of the following amino acids can be used in place of lysine, arginine, and histidine to remove the electrostatic charge but retain the hydrophilic nature of the side chain? |
A. | Aspartic acid and glutamic acid |
B. | Aspartic acid and glutamine |
C. | Asparagine and glutamic acid |
D. | Asparagine and glutamine |
Answer» E. | |
6. |
In tRNA charging, the Km (ATP) is unaffected in the heterodimer, but the Kcat is one half that of wild type enzyme. |
A. | False |
B. | True |
Answer» C. | |
7. |
Which of the following shaped structure is formed by the tRNATyr ? |
A. | J-shaped |
B. | O-shaped |
C. | I-shaped |
D. | L-shaped |
Answer» E. | |
8. |
The C-terminal domain of tyrosyl-tRNA synthetase contains major binding determinants for the tRNA. |
A. | False |
B. | True |
Answer» C. | |
9. |
Which of the following enzyme catalyzes the charging of tRNATyr with tyrosine? |
A. | Tyrosine synthetase |
B. | RNA activating enzyme |
C. | Tyrosyl-tRNA synthase |
D. | Tyrosyl-tRNA synthetase |
Answer» E. | |