MCQOPTIONS
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MCQOPTIONS
This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Protein Engineering knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
The digestion of IgG antibodies with pepsin produces how many fragments? |
| A. | Four |
| B. | One |
| C. | Three |
| D. | Two |
| Answer» E. | |
| 2. |
Which of the following is the cellular receptor of HIV-1 envelope glycoprotein gp120? |
| A. | CD12 |
| B. | CD3 |
| C. | CD8 |
| D. | CD4 |
| Answer» E. | |
| 3. |
The primary function of the linker in the ScFv molecule is to orientate the V domains into a specific structure to form the active binding site. |
| A. | True |
| B. | False |
| Answer» C. | |
| 4. |
Which of the following consists of antibody VL fused to a VH by a linker peptide? |
| A. | Humanized antibody |
| B. | Chimeric antibody |
| C. | Fragment of crystallization (Fc) |
| D. | Single-chain Variable fragment (ScFv) |
| Answer» E. | |
| 5. |
The digestion of IgG antibodies with papain produces how many fragments? |
| A. | Four |
| B. | One |
| C. | Two |
| D. | Three |
| Answer» E. | |
| 6. |
Which of the following is not true for the production of monoclonal antibodies by conventional methods? |
| A. | unsuitable for use |
| B. | Time-consuming |
| C. | Expensive |
| D. | Inexpensive |
| Answer» E. | |
| 7. |
Which of the following is a hybrid molecule that consists of non-identical heavy and light pairs, resulting in two different antigen specificities? |
| A. | Chimeric antibody |
| B. | Monoclonal antibody |
| C. | Humanized antibody |
| D. | Bispecific antibody |
| Answer» E. | |
| 8. |
How many complementarity-determining regions (CDRs) are present in an IgG molecule? |
| A. | Three |
| B. | Ten |
| C. | Six |
| D. | Twelve |
| Answer» E. | |
| 9. |
The hinge region is flexible and susceptible to proteolytic digestion. |
| A. | False |
| B. | True |
| Answer» C. | |
| 10. |
Which of the following bonds help in the association of antibody H and L chains? |
| A. | Peptide bonds |
| B. | Ionic bonds |
| C. | Hydrogen bonds |
| D. | Disulfide bonds |
| Answer» E. | |
| 11. |
Which of the following domains is responsible for antigen recognition and binding of antigens? |
| A. | C domains |
| B. | CH1 domain only |
| C. | CH1 and CH2 domains |
| D. | V domains |
| Answer» E. | |
| 12. |
The amino-terminal domains of both heavy and light chains are variable; in that, they differ in amino acid sequence from antibody to antibody. |
| A. | False |
| B. | True |
| Answer» C. | |
| 13. |
Which of the following technology has made it feasible to prepare large quantities of monoclonal antibodies (MAbs) with a defined antigen specificity? |
| A. | Southern blotting |
| B. | PCR |
| C. | rDNA technology |
| D. | Hybridoma technology |
| Answer» E. | |