MCQOPTIONS
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MCQOPTIONS
This section includes 23 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Antibodies in the human immune system can identify approximately 10 different molecules Which one of the following is correct? |
| A. | This diversity is generated from 10 |
| B. | different immunoglobin genes |
| C. | Many of these molecules are self-antigens |
| D. | Most of these antibodies recognize proteins |
| E. | Most of these antibodies recognize small organic molecules |
| Answer» D. Most of these antibodies recognize proteins | |
| 2. |
Which of those immunoglobulin classes is mainly found in external secretions? |
| A. | Ig A |
| B. | Ig D |
| C. | Ig M |
| D. | IgE |
| Answer» B. Ig D | |
| 3. |
Antigenic determinants bind to which portions of an antibody? |
| A. | Variable regions |
| B. | Constant regions |
| C. | Only light chains |
| D. | Only heavy chains |
| Answer» B. Constant regions | |
| 4. |
Monoclonal antibodies were first produced by |
| A. | Georges Kohler and Cesar Milstein |
| B. | Sarkar and Sommer |
| C. | Selman Waksman |
| D. | Edward Jenner and Louis Pasteur |
| Answer» B. Sarkar and Sommer | |
| 5. |
Structures of anti-PCP antibody shows that the tight binding of PCP to the antibody is primarily due to |
| A. | hydrophobic forces |
| B. | electrostatic forces. |
| C. | Van der Waals forces. |
| D. | none of these |
| Answer» B. electrostatic forces. | |
| 6. |
Antibodies of the IgG class |
| A. | consist of four subunits |
| B. | are glycoproteins |
| C. | are secreted into the bloodstream |
| D. | all of the above |
| Answer» E. | |
| 7. |
The human IgG class of antibodies is divided into |
| A. | five IgG classes |
| B. | two IgG classes |
| C. | three IgG classes |
| D. | four IgG classes |
| Answer» E. | |
| 8. |
A polyclonal antibody response |
| A. | is produced only in response to polymeric antigens |
| B. | is produced by several B cells recognizing different pitopes on the same antigen |
| C. | occurs during the lag phase of the immune response |
| D. | violates clonal selection |
| Answer» C. occurs during the lag phase of the immune response | |
| 9. |
Fab fragment has |
| A. | one antigen binding site |
| B. | two antigen binding site |
| C. | one antibody binding site |
| D. | two antibody binding site |
| Answer» B. two antigen binding site | |
| 10. |
The main function of antibodies is to |
| A. | kill all the foreign bodies |
| B. | generate antigens, thus conferring immunization |
| C. | protect the circulatory system |
| D. | chemically combine with the antigen which induces it, inactivate the antigen and protect the body from disease |
| Answer» E. | |
| 11. |
Which of the following are responsible for immune specificity? |
| A. | Antigens |
| B. | Antibodies |
| C. | T lymphocytes |
| D. | Macrophage |
| Answer» C. T lymphocytes | |
| 12. |
Alum is an effective adjuvant because it |
| A. | disaggregates the antigen. |
| B. | is immunogenic for stem cells |
| C. | is immunogenic for T cells |
| D. | slows the release of antigen |
| Answer» D. slows the release of antigen | |
| 13. |
A secondary antibody is an antibody that |
| A. | has been used in prior experiments |
| B. | is synthetically produced |
| C. | binds to another antibody |
| D. | is produced in boostered animals |
| Answer» D. is produced in boostered animals | |
| 14. |
The immunoglobulin fold is |
| A. | found only in IgG molecules |
| B. | a -barrel composed of a three- and a four-stranded antiparallel -sheet |
| C. | both (a) and (b) |
| D. | found six times in the IgG molecule |
| Answer» C. both (a) and (b) | |
| 15. |
Monoclonal refers to |
| A. | a single clone of antibody-producing cells |
| B. | all the antibody molecules which are identical |
| C. | the binding with same antigenic site with identical binding affinities |
| D. | all of the above |
| Answer» E. | |
| 16. |
Which species lack immunoglobulin light chains? |
| A. | Camels |
| B. | Humans |
| C. | cows |
| D. | Buffalo |
| Answer» B. Humans | |
| 17. |
Cleavage of an IgG molecule by a specific protease can produce |
| A. | an antigen-binding site and two constant regions |
| B. | two heavy chain-light chain dimers |
| C. | an inactive mixture of oligopeptides |
| D. | two Fab fragments and one Fc fragment |
| Answer» E. | |
| 18. |
Papain digest IgG into |
| A. | two Fab fragments and one Fc fragment |
| B. | three Fab fragments and two Fc fragments |
| C. | two Fab fragments and two Fc fragments |
| D. | three Fab fragments and three Fc fragments |
| Answer» B. three Fab fragments and two Fc fragments | |
| 19. |
The humoral immune response relies on the production of soluble proteins called |
| A. | antibodies |
| B. | macromolecules |
| C. | lymphocytes |
| D. | none of these |
| Answer» B. macromolecules | |
| 20. |
Antibodies can be used |
| A. | for the localization of proteins in the cell |
| B. | for protein purification |
| C. | to catalyze chemical reactions |
| D. | all of the above |
| Answer» E. | |
| 21. |
-Lymphocytes are often called simply |
| A. | B cells |
| B. | T cells |
| C. | T Lymphocytes |
| D. | none of these |
| Answer» B. T cells | |
| 22. |
Each IgA antibody molecule consists of |
| A. | four polypeptide chain and has two antigen binding site |
| B. | two polypeptide chain and has one antigen binding site |
| C. | three polypeptide chain and has two antigen binding site |
| D. | two polypeptide chain and has two antigen binding site |
| Answer» B. two polypeptide chain and has one antigen binding site | |
| 23. |
IgE provides |
| A. | immunity against some parasites |
| B. | complement killings of the cells and phagocytosis |
| C. | secretions in the body |
| D. | all of the above |
| Answer» B. complement killings of the cells and phagocytosis | |