Which of the following is true about tetanus acquired through traumatic wound ?

• A. Clostridium tetani travels via the nerves to the anterior horn dells in spinal cord
• B. The tetanospasmin component of the exotoxin act on the post-synaptic neurones and prevents impulse transmission
• C. The patient should be given tetanus toxoid intravenously
• D. Causes positive Nagler reaction