1.

Which of the following Factors causing Non-linearity?

A. Nonlinearity may arise due to pathological alteration at any one of the various pharmacokinetic steps, such as absorption, distribution and/or elimination.
B. Nonlinearity may arise due to Capacity-limited metabolism.
C. Nonlinearity may arise due to alteration in protein binding characteristics
D. All of the above
Answer» E.


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