Regarding the antiepileptic drugs

• A. Lorazepam has documented efficacy against absence seizures
• B. Phenytoin is able to stimulate its own metabolism by enzyme induction
• C. Valproate has a large Vd (>500l/70kg)
• D. The most common dose related adverse effects of Carbamazepine are ataxia and diplopia
• E. Vigabatrin works by sodium channel blockade