In an experiment, you wanted to see which mutation will have worse effect on transcription. In the 1st set you deleted 94 amino acids from the C-terminus and in the 2nd set you replace the 265th C-terminal arginine to cystine. Which in your opinion will have the worst effect?

• A. 94 amino acid mutant
• B. 265^th amino acid mutant
• C. Both will have similar negative effect
• D. No visible effect on rate of transcription