After occlusion of a coronary artery

• A. the ischaemia is most pronounced in the epicardial region
• B. loss of contractility only occurs when ultra structural changes in the myocyte are present
• C. reperfusion of the ischaemic area can result in new cellular damage, due to the generation of oxygen free radicals
• D. Q waves on the ECG are diagnostic of transmural infarction
• E. none of the above are true