1.

A malonic ester synthesis of a carboxylic acid proceeds by alkylation of the enolate of the malonic ester followed by ester hydrolysis and decarboxylation of the β-dicarboxylic acid. Which of the following carboxylic acids is difficult to prepare by this method?

A. PhCH2CH2CO2H
B. (CH3)2CHO2H
C. PhCH2CO2H
Answer» D.


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