Explore topic-wise MCQs in Microbiology.

This section includes 35 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.

1.

Negative strand ssRNA viruses need to have a preformed replicase when they invade a mammalian cell because they

A. use it to terminate transcripts when they copy host cell mRNA
B. have to make a positive strand copy that can be translated
C. use it to modify host enzymes that are recruited for viral replication
D. none of the above
Answer» C. use it to modify host enzymes that are recruited for viral replication
2.

Animal viruses with capsids displaying helical symmetry include

A. measles and mumps
B. influenza
C. rabies
D. all of these
Answer» E.
3.

Icosahedral viruses are generally

A. polio viruses
B. adeno viruses
C. both (a) and (b)
D. none of these
Answer» D. none of these
4.

Negri bodies are found in cells infected with

A. Paramyxoviruses
B. Vaccinia virus
C. Fowlpox virus
D. Rabies virus
Answer» E.
5.

Which of the following virus is transmitted by genital route?

A. Papillomaviruses
B. Herpes simplex virus type 2
C. Hepatitis B virus
D. All of these
Answer» E.
6.

The RNA sarcoma viruses, the most strongly transforming viruses may transform which of the following cells in a culture?

A. fibroblasts
B. myoblasts
C. iris epithelial
D. all of these
Answer» E.
7.

The predominant lipid substance found in the viral envelope is

A. phospholipids
B. glycolipids
C. neutral fat
D. all of these
Answer» B. glycolipids
8.

The structural abnormality of cells is termed as

A. hyperplasia
B. anaplasia
C. metastasis
D. all of these
Answer» C. metastasis
9.

Transfer of infection from cell to cell occurs mainly by direct transfer of virions via

A. plasmodesmata
B. cytodesmata
C. protodesmata
D. none of these
Answer» B. cytodesmata
10.

Interanuclear inclusion bodies are found in cells infected with

A. Parvoviruses
B. Herpesviruses
C. Adenoviruses
D. all of these
Answer» E.
11.

What is the function of positive strand in double stranded RNA viruses?

A. Synthesis of protein
B. Production of ribosomes
C. Both (a) and (b)
D. None of these
Answer» B. Production of ribosomes
12.

Plant viruses penetrate host cells through transient ores called

A. ectodesmata
B. endodesmata
C. cytodesmata
D. protodesmata
Answer» B. endodesmata
13.

Which of the following virus is transmitted by the respiratory route?

A. Rhinovirus
B. Coronavirus
C. Measles virus
D. All of these
Answer» E.
14.

Supercoiling refers to the extra turns in the structure of ds DNA due to the action of

A. DNA gyrase
B. DNA pyrase
C. RNA gyrase
D. RNA pyrase
Answer» B. DNA pyrase
15.

The transcription of the viral nucleic acid into mRNA is not necessary in case of

A. RNA viruses
B. ds DNA viruses
C. ss DNA viruses
D. all of these
Answer» B. ds DNA viruses
16.

The reovirus and influenza virus contain

A. 10 different segments of dsRNA and 8 different segments of ssRNA respectively
B. 8 different segments of dsRNA and 10 different segments of ssRNA respectively
C. 5 different segments of dsRNA and 7 different segments of ssRNA respectively
D. 7 different segments of dsRNA and 5different segments of ssRNA respectively
Answer» B. 8 different segments of dsRNA and 10 different segments of ssRNA respectively
17.

The microbes which are most likely to be completely dependent on a plant or animal host are

A. viruses
B. bacteria
C. fungi
D. algae
Answer» B. bacteria
18.

The two major components of viruses are

A. fat and protein
B. nucleic acid and protein
C. carbohydrate and nucleic acid
D. fat and carbohydrate
Answer» C. carbohydrate and nucleic acid
19.

The penetration of animal viruses into attached cells occur by mechanisms consisting of engulfment of whole virions by the cells in a phagocytic process called

A. vitropexis
B. viropexis
C. ectodesmata
D. vivopexis
Answer» C. ectodesmata
20.

West Nile virus can cause a disease in human beings that may be transmitted from an infected bird to a person by a mosquito. This is an example of

A. endogenous infection
B. fomite borne disease
C. arthropod borne disease
D. nosocomial infection
Answer» D. nosocomial infection
21.

Influenza virus undergoes antigenic shift resulting in major antigenic changes by which of the following mechanisms?

A. Somatic recombination of heavy and light chains
B. Expression of several different capsule types
C. Changing the receptor binding canyon that docks with the host receptor
D. Reassortment of RNA segments from different influenza viruses
Answer» E.
22.

The nucleocapsid is covered by an outer membrane like structure called

A. envelope
B. covering
C. membronocapsid
D. all of these
Answer» B. covering
23.

Which type of interferon is produced by virus-infected cells?

A.
B.
C. Both (a) and (b)
D. None of these
Answer» D. None of these
24.

Fluorescence microscopy can be used for the diagnosis of

A. Subacute sclerosing panencephalitis
B. Herpes simplex encephalitis
C. Rabies
D. All of these
Answer» E.
25.

Viral matrix proteins are

A. exposed on the surface of the virus
B. found mainly on naked viruses
C. anchor the envelope of enveloped viruses
D. part of the nucleoprotein core of viruses
Answer» D. part of the nucleoprotein core of viruses
26.

Which of the following reflects the correct order of events that take place during the multiplication of a virus?

A. Attachment, penetration, maturation, biosynthesis, release
B. Penetration, attachment, biosynthesis, maturation, release
C. Attachment, penetration, biosynthesis, maturation, release
D. Attachment, release, biosynthesis, maturation, penetration
Answer» D. Attachment, release, biosynthesis, maturation, penetration
27.

What can be coated to the plastic dish if an ELISA is performed to directly detect polio virus?

A. Patient serum
B. Anti-polio antibody
C. Polio capsid protein
D. Colored substrate
Answer» C. Polio capsid protein
28.

What does the positive strand in double stranded RNA viruses stands for?

A. rRNA
B. tRNA
C. mRNA
D. None of these
Answer» D. None of these
29.

Which of the following characteristics would not be used to classify viruses?

A. Type of cell wall structure
B. Type of nucleic acid
C. Presence of an envelope
D. Symmetry
Answer» B. Type of nucleic acid
30.

Intracytoplasmic inclusion bodies are found in cells infected with

A. Rabies virus
B. Vaccinia virus
C. Fowlpox virus
D. all of these
Answer» E.
31.

Which type of interferon is produced by T lymphocytes?

A.
B.
C.
D. and
Answer» D. and
32.

Viropexis takes place in the phagocytic vacuoles and is due to the action of enzymes

A. DNA gyrase
B. lysosomal protease
C. lysosomal lipase
D. all of these
Answer» C. lysosomal lipase
33.

The uncontrolled proliferation of cells is termed as

A. hyperplasia
B. anaplasia
C. metastasis
D. all of these
Answer» B. anaplasia
34.

The tissue structure deteriorates as the virus multiplies. This deterioration is called

A. aneuploidy
B. protopathic effect
C. cytopathic effect
D. none of these
Answer» D. none of these
35.

Mumps vaccine is prepared from the cultures of

A. chick fibroblasts
B. African green monkey cells
C. healthy calves
D. sheep
Answer» B. African green monkey cells