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				This section includes 128 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Which of the following virus is transmitted by genital route? | 
| A. | Papillomaviruses | 
| B. | Herpes simplex virus type 2 | 
| C. | Hepatitis B virus | 
| D. | All of these | 
| Answer» E. | |
| 2. | Negri bodies are found in cells infected with | 
| A. | Paramyxoviruses | 
| B. | Vaccinia virus | 
| C. | Fowlpox virus | 
| D. | Rabies virus | 
| Answer» E. | |
| 3. | The uncontrolled proliferation of cells is termed as | 
| A. | hyperplasia | 
| B. | anaplasia | 
| C. | metastasis | 
| D. | all of these | 
| Answer» B. anaplasia | |
| 4. | The RNA sarcoma viruses, the most strongly transforming viruses may transform which of the following cells in a culture? | 
| A. | fibroblasts | 
| B. | myoblasts | 
| C. | iris epithelial | 
| D. | all of these | 
| Answer» E. | |
| 5. | Plant viruses penetrate host cells through transient ores called | 
| A. | ectodesmata | 
| B. | endodesmata | 
| C. | cytodesmata | 
| D. | protodesmata | 
| Answer» B. endodesmata | |
| 6. | Negative strand ssRNA viruses need to have a preformed replicase when they invade a mammalian cell because they | 
| A. | use it to terminate transcripts when they copy host cell mRNA | 
| B. | have to make a positive strand copy that can be translated | 
| C. | use it to modify host enzymes that are recruited for viral replication | 
| D. | none of the above | 
| Answer» C. use it to modify host enzymes that are recruited for viral replication | |
| 7. | Which of the following reflects the correct order of events that take place during the multiplication of a virus? | 
| A. | Attachment, penetration, maturation, biosynthesis, release | 
| B. | Penetration, attachment, biosynthesis, maturation, release | 
| C. | Attachment, penetration, biosynthesis, maturation, release | 
| D. | Attachment, release, biosynthesis, maturation, penetration | 
| Answer» D. Attachment, release, biosynthesis, maturation, penetration | |
| 8. | Influenza virus undergoes antigenic shift resulting in major antigenic changes by which of the following mechanisms? | 
| A. | Somatic recombination of heavy and light chains | 
| B. | Expression of several different capsule types | 
| C. | Changing the receptor binding canyon that docks with the host receptor | 
| D. | Reassortment of RNA segments from different influenza viruses | 
| Answer» E. | |
| 9. | The reovirus and influenza virus contain | 
| A. | 10 different segments of dsRNA and 8 different segments of ssRNA respectively | 
| B. | 8 different segments of dsRNA and 10 different segments of ssRNA respectively | 
| C. | 5 different segments of dsRNA and 7 different segments of ssRNA respectively | 
| D. | 7 different segments of dsRNA and 5different segments of ssRNA respectively | 
| Answer» B. 8 different segments of dsRNA and 10 different segments of ssRNA respectively | |
| 10. | Which of the following is responsible for a musty or earthy flavor? | 
| A. | Actinomycetes | 
| B. | Flavobacterium | 
| C. | both (a) and (b) | 
| D. | Pseudomonas syncyanea | 
| Answer» B. Flavobacterium | |
| 11. | Anthracnose is a defect which can be observed as | 
| A. | spotting of leaves | 
| B. | spotting of seedpods | 
| C. | spotting of fruits | 
| D. | all of these | 
| Answer» E. | |
| 12. | Saprophytic bacteria cause | 
| A. | sliminess or souring in piled, wet and heating vegetables | 
| B. | brown rot in vegetables | 
| C. | black rot in fruits | 
| D. | bacterial soft rot | 
| Answer» B. brown rot in vegetables | |
| 13. | Pink rots in eggs is caused by the strains of | 
| A. | Pseudomonas | 
| B. | Pseudomonas fluorescens | 
| C. | species of Micrococcus or Bacillus | 
| D. | none of the above | 
| Answer» B. Pseudomonas fluorescens | |
| 14. | Which of the following is the spike antigen of HIV-I? | 
| A. | gp 120 | 
| B. | gp 140 | 
| C. | gp 36 | 
| D. | gp 41 | 
| Answer» B. gp 140 | |
| 15. | The acidity may be described as "aromatic" when | 
| A. | Lactic streptococci and aroma forming Leuconostoc species are growing together | 
| B. | Streptococcus lactis and other lactis are growing together | 
| C. | appreciable amounts of volatile fatty acids are produced by Coliform bacteria | 
| D. | all of the above | 
| Answer» B. Streptococcus lactis and other lactis are growing together | |
| 16. | Bacterial ropiness in milk is caused by | 
| A. | slimy capsular material from the cells usually gums or mucins | 
| B. | slimy capsular material from the cells usually proteins | 
| C. | slimy capsular material from the cells usually lipids | 
| D. | all of the above | 
| Answer» B. slimy capsular material from the cells usually proteins | |
| 17. | Which of the cause(s) has/have been suggested for the chill rings in sausage? | 
| A. | Oxidation | 
| B. | Production of organic acids or reducing substances by bacteria | 
| C. | Excessive water | 
| D. | all of the above | 
| Answer» E. | |
| 18. | An alkaline reaction in milk is caused by the alkali formers bacteria as | 
| A. | Pseudomonas fluorescens | 
| B. | A. viscolactis | 
| C. | both (a) and (b) | 
| D. | none of these | 
| Answer» D. none of these | |
| 19. | Black spot in meat are produced mainly by | 
| A. | Cladosporium | 
| B. | Thamnidium | 
| C. | Mucor | 
| D. | Rhizopus | 
| Answer» B. Thamnidium | |
| 20. | The yoghurt is made from | 
| A. | Lactobacillus bulgaricus | 
| B. | Streptococcus thermophilus | 
| C. | S. cremoris | 
| D. | mixed culture of (a) and (b) | 
| Answer» E. | |
| 21. | Cheese cancer of Swiss and similar cheese is caused by | 
| A. | Oospora Crustacea | 
| B. | Oospora caseovorans | 
| C. | Oospora aurianticum | 
| D. | none of these | 
| Answer» C. Oospora aurianticum | |
| 22. | Esters like flavors in butter are resulted from the action of | 
| A. | P. mephitica | 
| B. | Aeromonas hydrophila | 
| C. | P. fragi | 
| D. | Pseudomonas synxantha | 
| Answer» D. Pseudomonas synxantha | |
| 23. | Watery soft rot is found mostly in | 
| A. | fruits | 
| B. | vegetables | 
| C. | cereals | 
| D. | all of these | 
| Answer» C. cereals | |
| 24. | A viral load test detects the | 
| A. | provirus of HIV in infected cells | 
| B. | total amount of virus in the infected host | 
| C. | number of viruses being released by each infected cell | 
| D. | amount of bacteriophage being produced by E. coli cells | 
| Answer» B. total amount of virus in the infected host | |
| 25. | Colorless rots in eggs is caused by | 
| A. | Pseudomonas alcaligenes | 
| B. | Pseudomonas fluorescens | 
| C. | both (a) and (b) | 
| D. | none of these | 
| Answer» B. Pseudomonas fluorescens | |
| 26. | Bulgarian butter milk is made with the help of | 
| A. | Lactobacillus bulgaricus | 
| B. | Streptococcus lactis | 
| C. | Streptococcus thermophilus | 
| D. | S. cremoris | 
| Answer» B. Streptococcus lactis | |
| 27. | Which of the following microorganism spoil poultry in polyethylene bags? | 
| A. | Pseudomonas-achromobacter | 
| B. | Alcaligenes | 
| C. | hetero-fermentative species | 
| D. | catalase negative bacteria | 
| Answer» B. Alcaligenes | |
| 28. | The problem(s) associated with development of a vaccine against HIV is/are | 
| A. | antibody alone may be insufficient | 
| B. | rapid mutation of HIV | 
| C. | virus can spread from cell to cell by fusion to produce syncytia | 
| D. | all of these | 
| Answer» E. | |
| 29. | Cheese with too low an acidity because of the addition of cream or the failure of the starter often is made gelatinous or slimy by | 
| A. | Pseudomonas | 
| B. | P. fragi | 
| C. | Alcaligenes metalcaligenes | 
| D. | all of these | 
| Answer» E. | |
| 30. | Which of the following species of Clostridium is responsible for formation of dark green to black colours in cheese? | 
| A. | Clostridium tyrobutyricum | 
| B. | Clostridium sporogenes | 
| C. | Clostridium herbarum | 
| D. | None of these | 
| Answer» D. None of these | |
| 31. | Which of the following (s) is/are responsible for the green patches on the surface of meats under aerobic conditions? | 
| A. | P. expansum | 
| B. | P. asperulum | 
| C. | P. oxalicum | 
| D. | All of these | 
| Answer» E. | |
| 32. | The cells most oftenly infected by HIV are | 
| A. | Null cells | 
| B. | CD8 + T lymphocytes | 
| C. | CD4 + T lymphocytes | 
| D. | None of these | 
| Answer» D. None of these | |
| 33. | More spoilage of eggs is caused by | 
| A. | bacteria than molds | 
| B. | molds than bacteria | 
| C. | synergistically | 
| D. | none of these | 
| Answer» B. molds than bacteria | |
| 34. | Non bacterial ropiness or sliminess in milk and milk products may be due to the | 
| A. | stringiness caused by mastitis and in particular by fibrin and leucocytes from the cow's blood. | 
| B. | sliminess resulting from the thickness of the cream | 
| C. | stringiness due to thin films of casein or lactalbumin during cooling | 
| D. | all of the above | 
| Answer» E. | |
| 35. | The greening of sausage may appear as a green ring not far from the casing, a green core, or a green surface. The cause of greening is the production of hydrogen peroxide by | 
| A. | hetero-fermentative species | 
| B. | catalase negative bacteria | 
| C. | both (a) and (b) | 
| D. | none of these | 
| Answer» D. none of these | |
| 36. | Unopened, sliced bacon, packaged in material somewhat highly resistant to oxygen permeability, is spoiled mostly by | 
| A. | Lactobacilli | 
| B. | Micrococci | 
| C. | fecal Streptococci | 
| D. | molds | 
| Answer» B. Micrococci | |
| 37. | What is the average incubation period for development of AIDS? | 
| A. | One year | 
| B. | Five years | 
| C. | Ten years | 
| D. | Twenty years | 
| Answer» D. Twenty years | |
| 38. | The commonest opportunistic infection in AIDS patient in India is | 
| A. | cryptosporidiosis | 
| B. | toxoplasmosis | 
| C. | tuberculosis | 
| D. | cryptococcosis | 
| Answer» D. cryptococcosis | |
| 39. | Pseudomonas nigrifaciens in mildly salted butter may cause | 
| A. | black smudge | 
| B. | greenish areas | 
| C. | pink color | 
| D. | none of these | 
| Answer» B. greenish areas | |
| 40. | Black mold rot is caused by | 
| A. | A.flavus | 
| B. | A. niger | 
| C. | Trichoderma | 
| D. | Trichothecium roseum | 
| Answer» C. Trichoderma | |
| 41. | HIV or Human Immunodeficiency Virus is considered unique because each virus contains: | 
| A. | more than 100 copies of the viral genome | 
| B. | a genome made up of both DNA and RNA components | 
| C. | a viral enzyme known as reverse transcriptase | 
| D. | sticky proteins that allow it to bind tightly to host cells | 
| Answer» D. sticky proteins that allow it to bind tightly to host cells | |
| 42. | The reovirus and influenza virus contain | 
| A. | 10 different segments of dsRNA and 8 different segments of ssRNA respectively | 
| B. | 8 different segments of dsRNA and 10 different segments of ssRNA respectively | 
| C. | 5 different segments of dsRNA and 7 different segments of ssRNA respectively | 
| D. | 7 different segments of dsRNA and 5different segments of ssRNA respectively | 
| Answer» B. 8 different segments of dsRNA and 10 different segments of ssRNA respectively | |
| 43. | Which of the following characteristics would not be used to classify viruses? | 
| A. | Type of cell wall structure | 
| B. | Type of nucleic acid | 
| C. | Presence of an envelope | 
| D. | Symmetry | 
| Answer» B. Type of nucleic acid | |
| 44. | Viral matrix proteins are | 
| A. | exposed on the surface of the virus | 
| B. | found mainly on naked viruses | 
| C. | anchor the envelope of enveloped viruses | 
| D. | part of the nucleoprotein core of viruses | 
| Answer» D. part of the nucleoprotein core of viruses | |
| 45. | The nucleocapsid is covered by an outer membrane like structure called | 
| A. | envelope | 
| B. | covering | 
| C. | membronocapsid | 
| D. | all of these | 
| Answer» B. covering | |
| 46. | Which type of interferon is produced by virus-infected cells? | 
| A. | α | 
| B. | β | 
| C. | Both (a) and (b) | 
| D. | None of these | 
| Answer» D. None of these | |
| 47. | Influenza virus undergoes antigenic shift resulting in major antigenic changes by which of the following mechanisms? | 
| A. | Somatic recombination of heavy and light chains | 
| B. | Expression of several different capsule types | 
| C. | Changing the receptor binding canyon that docks with the host receptor | 
| D. | Reassortment of RNA segments from different influenza viruses | 
| Answer» E. | |
| 48. | Which of the following virus is transmitted by the respiratory route? | 
| A. | Rhinovirus | 
| B. | Coronavirus | 
| C. | Measles virus | 
| D. | All of these | 
| Answer» E. | |
| 49. | What is the function of positive strand in double stranded RNA viruses? | 
| A. | Synthesis of protein | 
| B. | Production of ribosomes | 
| C. | Both (a) and (b) | 
| D. | None of these | 
| Answer» B. Production of ribosomes | |
| 50. | Intracytoplasmic inclusion bodies are found in cells infected with | 
| A. | Rabies virus | 
| B. | Vaccinia virus | 
| C. | Fowlpox virus | 
| D. | all of these | 
| Answer» E. | |