MCQOPTIONS
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MCQOPTIONS
This section includes 43 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which eukaryotic RNA polymerase makes tRNA's? |
| A. | RNA polymerase 1 |
| B. | RNA polymerase 2 |
| C. | RNA polymerase 3 |
| D. | Any of these |
| Answer» D. Any of these | |
| 2. |
Which of these catalyzes the synthesis of RNA from a DNA template? |
| A. | DNA gyrase |
| B. | DNA ligase |
| C. | DNA polymerase |
| D. | RNA polymerase |
| Answer» E. | |
| 3. |
The major function of RNA polymerase's sigma factor is |
| A. | recognition of the translational stop sequence |
| B. | recognition of the transcriptional start sequence |
| C. | recognition of the transcriptional stop sequence |
| D. | recognition of the translational start sequence |
| Answer» C. recognition of the transcriptional stop sequence | |
| 4. |
Which of the following transcription termination technique has RNA dependent ATPase activity? |
| A. | Intercalating agents |
| B. | Rho dependent |
| C. | Rho independent |
| D. | Rifampcin |
| Answer» C. Rho independent | |
| 5. |
How many base pairs of DNA is transcribed by RNA polymerase in one go? |
| A. | 5-6 |
| B. | 3 |
| C. | 4 |
| D. | 7-8 |
| Answer» E. | |
| 6. |
Which of the following is used to describe the time taken by RNA polymerase to leave the promoter? |
| A. | Promoter clearance time |
| B. | Abortive initiation |
| C. | Elongation factor |
| D. | Mean time |
| Answer» B. Abortive initiation | |
| 7. |
Name the sigma factor which is used for promoter recognition? |
| A. | Sigma 32 |
| B. | Sigma 70 |
| C. | Sigma 60 |
| D. | Sigma 40 |
| Answer» C. Sigma 60 | |
| 8. |
In bacteria, binding of _________ factor to the RNA polymerase increases its affinity for promoter sites in the DNA. |
| A. | alpha |
| B. | sigma |
| C. | rho |
| D. | beta |
| Answer» C. rho | |
| 9. |
Which enzyme makes the transcription, an essentially irreversible process? |
| A. | pyrophosphatase |
| B. | amylase |
| C. | glucamylase |
| D. | topoisomerase |
| Answer» B. amylase | |
| 10. |
The transcription factors assist the RNA polymerase in locating ________________ |
| A. | stop codon |
| B. | mutation |
| C. | active site |
| D. | promoter |
| Answer» E. | |
| 11. |
Which of the two strands of DNA will be transcribed is determined by the _______________ |
| A. | RNA polymerase |
| B. | DNA polymerase |
| C. | Promoter sequence |
| D. | Inducer sequence |
| Answer» D. Inducer sequence | |
| 12. |
Promoter is a ____________________ |
| A. | gene |
| B. | site on DNA |
| C. | site on RNA |
| D. | toxin |
| Answer» C. site on RNA | |
| 13. |
Which of the following enzymes are used in the process of transcription? |
| A. | DNA polymerases |
| B. | RNA polymerases |
| C. | DNA helicase |
| D. | DNA topoisomerase |
| Answer» C. DNA helicase | |
| 14. |
Which of the following play a role in structural support? |
| A. | rRNA |
| B. | mRNA |
| C. | tDNA |
| D. | tRNA |
| Answer» B. mRNA | |
| 15. |
RNA is a mobile nucleic acid. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 16. |
After transcribing into RNA, the gene is spliced out of the genome. |
| A. | True |
| B. | False |
| Answer» C. | |
| 17. |
Transcription is the synthesis of ______________________ |
| A. | RNA |
| B. | DNA |
| C. | Protein |
| D. | Polypeptide |
| Answer» B. DNA | |
| 18. |
What is the intermediate between a gene and its polypeptide? |
| A. | mRNA |
| B. | tRNA |
| C. | rRNA |
| D. | siRNA |
| Answer» B. tRNA | |
| 19. |
In patients of sickle cell anemia, the hemoglobin contains a substitution for ____________________ |
| A. | glutamic acid |
| B. | ascorbic acid |
| C. | carboxylic acid |
| D. | quinone |
| Answer» B. ascorbic acid | |
| 20. |
Which proteolytic enzyme was used in the experiments aimed at elucidating the mutation that causes sickle cell anemia? |
| A. | papain |
| B. | rennin |
| C. | pepsin |
| D. | trypsin |
| Answer» E. | |
| 21. |
Which organism was used for experiments that led to “one gene – one enzyme” hypothesis? |
| A. | Neurospora |
| B. | Nematode |
| C. | Mus musculus |
| D. | Drosophila |
| Answer» B. Nematode | |
| 22. |
When was the link between enzymes and inherited disease first elucidated? |
| A. | 1708 |
| B. | 1808 |
| C. | 1908 |
| D. | 2008 |
| Answer» D. 2008 | |
| 23. |
Which of the following proteins first binds to TATA box during transcription? |
| A. | TF II D |
| B. | TF II A |
| C. | RNA polymerase |
| D. | TF II B |
| Answer» B. TF II A | |
| 24. |
A level of regulation, demonstrated by the termination of transcription if tryptophan is abundant, by the tryptophan operon in E.coli cells is called |
| A. | attenuation |
| B. | activation |
| C. | desiccation |
| D. | corepression |
| Answer» D. corepression | |
| 25. |
Recognition/binding site of RNA polymerase is called |
| A. | promoter |
| B. | receptor |
| C. | terminator |
| D. | facilitator |
| Answer» B. receptor | |
| 26. |
Which eukaryotic RNA polymerase makes tRNA\'s? |
| A. | RNA polymerase 2 |
| B. | RNA polymerase 1 |
| C. | Any of these |
| D. | RNA polymerase 3 |
| Answer» E. | |
| 27. |
The synthesis of mRNA based on a DNA template is called |
| A. | transcription |
| B. | DNA replication |
| C. | DNA restriction |
| D. | translation |
| Answer» B. DNA replication | |
| 28. |
A specific __________ factor helps RNA polymerase bind to late promoters and transcribe late genes. |
| A. | beta |
| B. | sigma |
| C. | gamma |
| D. | delta |
| Answer» D. delta | |
| 29. |
The location of first hexameric sequence typically found in pro-karyotic promoters is |
| A. | approximately 35 bases upstream of the transcription start site |
| B. | at the transcription start site |
| C. | approximately 25 bases upstream of the transcription start site |
| D. | approximately 10 bases upstream of the transcription start site |
| Answer» B. at the transcription start site | |
| 30. |
WHICH_OF_THE_FOLLOWING_IS_USED_TO_DESCRIBE_THE_TIME_TAKEN_BY_RNA_POLYMERASE_TO_LEAVE_THE_PROMOTER??$ |
| A. | Promoter clearance time |
| B. | Abortive initiation |
| C. | Elongation factor |
| D. | Mean time |
| Answer» B. Abortive initiation | |
| 31. |
NAME_THE_SIGMA_FACTOR_WHICH_IS_USED_FOR_PROMOTER_RECOGNITION??$ |
| A. | Sigma 32 |
| B. | Sigma 70 |
| C. | Sigma 60 |
| D. | Sigma 40 |
| Answer» C. Sigma 60 | |
| 32. |
Which of the following transcription termination technique has RNA dependent ATPase activity?$ |
| A. | Intercalating agents |
| B. | Rho dependent |
| C. | Rho independent |
| D. | Rifampcin |
| Answer» C. Rho independent | |
| 33. |
How many base pairs of DNA is transcribed by RNA polymerase in one go?$ |
| A. | 5-6 |
| B. | 3 |
| C. | 4 |
| D. | 7-8 |
| Answer» E. | |
| 34. |
Mark the one, which is NOT the transcription inhibitor in eukaryotes. |
| A. | Rifampicin |
| B. | Acridine dye |
| C. | Actinomycin D |
| D. | Rho factor |
| Answer» E. | |
| 35. |
Name the one intrinsic terminator of transcription. |
| A. | Intercalating agents |
| B. | Rho independent |
| C. | Rho dependent |
| D. | Acridine orange |
| Answer» C. Rho dependent | |
| 36. |
What is the work of the sigma factor in transcription? |
| A. | Helicase action |
| B. | Transcription initiation |
| C. | Transcription elongation |
| D. | Transcription termination |
| Answer» C. Transcription elongation | |
| 37. |
Which of the following ensure stable binding of RNA polymerase at the promoter site? |
| A. | DNA photolyase |
| B. | Sigma factor |
| C. | DNA glycosylase |
| D. | RecA |
| Answer» C. DNA glycosylase | |
| 38. |
Who discovered RNA polymerase? |
| A. | Samuel B. Weiss |
| B. | Nirenberg |
| C. | Watson and Crick |
| D. | Darwin |
| Answer» B. Nirenberg | |
| 39. |
Which of the following is TRUE for the RNA polymerase activity? |
| A. | DNA dependent DNA synthesis |
| B. | Direct repair |
| C. | DNA dependent RNA synthesis |
| D. | RNA dependent RNA synthesis |
| Answer» D. RNA dependent RNA synthesis | |
| 40. |
Name the site where upstream sequences located? |
| A. | Prior to start point |
| B. | After the startpoint |
| C. | Right border of DNA |
| D. | In the middle of DNA |
| Answer» B. After the startpoint | |
| 41. |
Mark the statement which is INCORRECT about the transcription unit? |
| A. | It is a transcribed segment of DNA |
| B. | Eukaryotes have monocistronic transcription unit |
| C. | Prokaryotes also have a monocistronic transcription unit |
| D. | Immediate product of transcription is primary transcript |
| Answer» D. Immediate product of transcription is primary transcript | |
| 42. |
Like replication, transcription also occurs bidirectionally. |
| A. | True |
| B. | False |
| Answer» C. | |
| 43. |
The process of formation of RNA is known as___________ |
| A. | Replication |
| B. | DNA repair |
| C. | Translation |
| D. | Transcription |
| Answer» E. | |