 
			 
			MCQOPTIONS
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				This section includes 16 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Binding of the large subunit to the small subunit triggers a cascade of reactions. Arrange them in order of their occurrence. | 
| A. | ii, iv, i, iii | 
| B. | iii, i, ii, iv | 
| C. | iv, ii, i, iii | 
| D. | i, iii, ii, ivView Answer | 
| Answer» B. iii, i, ii, iv | |
| 2. | When the large and small subunit of ribosome associate which of the following is not found within the complex? | 
| A. | IF1 | 
| B. | IF2 | 
| C. | IF3 | 
| D. | mRNA | 
| Answer» D. mRNA | |
| 3. | Which of the following is not the function of IF3? | 
| A. | Binds to the small subunit | 
| B. | Helps dissociate the 70S ribosome after translation | 
| C. | Helps associate the large and small subunits during translation | 
| D. | Blocks the binding of the charged tRNA molecule to the small subunit | 
| Answer» D. Blocks the binding of the charged tRNA molecule to the small subunit | |
| 4. | Which of the following is a GTPase? | 
| A. | IF1 | 
| B. | IF2 | 
| C. | IF3 | 
| D. | eIF1A | 
| Answer» C. IF3 | |
| 5. | Changing the positioning of the ribosome leads to the synthesis of different proteins. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 6. | WHICH_OF_THE_FOLLOWING_IS_A_GTPASE??$ | 
| A. | IF1 | 
| B. | IF2 | 
| C. | IF3 | 
| D. | eIF1A | 
| Answer» C. IF3 | |
| 7. | When the large and small subunit of ribosome associate which of the following is not found within the complex?$ | 
| A. | IF1 | 
| B. | IF2 | 
| C. | IF3 | 
| D. | mRNA | 
| Answer» D. mRNA | |
| 8. | Which_of_the_following_is_not_the_function_of_IF3?$ | 
| A. | Binds to the small subunit | 
| B. | Helps dissociate the 70S ribosome after translation | 
| C. | Helps associate the large and small subunits during translation | 
| D. | Blocks the binding of the charged tRNA molecule to the small subunit | 
| Answer» D. Blocks the binding of the charged tRNA molecule to the small subunit | |
| 9. | How many translation initiation factors work hand in hand to initiate prokaryotic translation? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» D. 4 | |
| 10. | Deformylase has a crucial role to play in the formation of mature polypeptide chains in prokaryotes. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 11. | The first amino acid to be incorporated in the prokaryotic polypeptide is ____________ | 
| A. | Methionine | 
| B. | Valine | 
| C. | N-formyl methionine | 
| D. | N-acyl valine | 
| Answer» D. N-acyl valine | |
| 12. | The initiation of translation requires a special type of tRNA to bind to the ORF of the mRNA. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 13. | In case of prokaryotes the first tRNA enters the ribosome in the ____________ | 
| A. | A site | 
| B. | P site | 
| C. | E site | 
| D. | Already attached to the mRNA before ribosome association | 
| Answer» C. E site | |
| 14. | What kind of interactions results in the binding of mRNA and the ribosome? | 
| A. | Hydrophobic interaction | 
| B. | Hydrophilic interaction | 
| C. | Ionic interaction | 
| D. | Hydrogen bonding | 
| Answer» E. | |
| 15. | Changing in the positioning of the ribosome leads to the synthesis of different proteins. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 16. | For the translation to be initiated which of the following does not occur? | 
| A. | Ribosome recruitment to the mRNA | 
| B. | Positioning of ribosome on ‘GUG’ | 
| C. | Addition of charged tRNA to the A site | 
| D. | Binding of the large and small subunits of the ribosome | 
| Answer» D. Binding of the large and small subunits of the ribosome | |