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This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of them is used to introduce negative supercoiling in DNA? |
| A. | Type 1 topoisomerase |
| B. | Ethidium bromide |
| C. | Gyrase/ type 2 topoisomerase |
| D. | SYBR gold |
| Answer» D. SYBR gold | |
| 2. |
What is the term given to the supercoiling of circular DNA? |
| A. | Twist number |
| B. | Linking number |
| C. | Writhe number |
| D. | Cross-linking |
| Answer» C. Writhe number | |
| 3. |
Double-stranded DNA with high GC content has higher thermal stability than that of lower GC content? |
| A. | True |
| B. | False |
| Answer» B. False | |
| 4. |
DOUBLE-STRANDED_DNA_WITH_HIGH_GC_CONTENT_HAS_HIGHER_THERMAL_STABILITY_THAN_THAT_OF_LOWER_GC_CONTENT??$ |
| A. | True |
| B. | False |
| Answer» B. False | |
| 5. |
Which of them is used to introduce negative supercoiling in DNA?$ |
| A. | Type 1 topoisomerase |
| B. | Ethidium bromide |
| C. | Gyrase/ type 2 topoisomerase |
| D. | SYBR gold |
| Answer» D. SYBR gold | |
| 6. |
What_is_the_term_given_to_the_supercoiling_of_circular_DNA?$ |
| A. | Twist number |
| B. | Linking number |
| C. | Writhe number |
| D. | Cross-linking |
| Answer» C. Writhe number | |
| 7. |
Which of this factor is not responsible for thermal denaturation of DNA? |
| A. | PH |
| B. | Temperature |
| C. | Ionic strength |
| D. | Humidity |
| Answer» E. | |
| 8. |
The stability and formation of G-quadruplex depends on __________ |
| A. | Monovalent cation |
| B. | Divalent cation |
| C. | Bivalent cation |
| D. | Pentavalent ion |
| Answer» B. Divalent cation | |
| 9. |
Name the nitrogenous base which is found in abundance in G-quadruplex? |
| A. | Adenine |
| B. | Guanine |
| C. | Cytosine |
| D. | Thymine |
| Answer» C. Cytosine | |
| 10. |
The third strand of triple helix is paired in which scheme? |
| A. | Hoogsteen base pair scheme |
| B. | Intermolecular base pair scheme |
| C. | Intramolecular base pair scheme |
| D. | G-quartet scheme |
| Answer» B. Intermolecular base pair scheme | |
| 11. |
Which one of the following statement is INCORRECT for Z-DNA? |
| A. | Left-handed DNA |
| B. | Mostly found in alternating purine-pyrimidine sequences |
| C. | Only one deep, narrow groove |
| D. | Anti glycosidic bond conformation |
| Answer» E. | |
| 12. |
How many base pairs are there in every helical turn of Watson-Crick double helix model? |
| A. | 32.3 |
| B. | 11.6 |
| C. | 20 |
| D. | 10.4 |
| Answer» E. | |
| 13. |
Which form of DNA is described by Watson-Crick model? |
| A. | B-DNA |
| B. | Z-DNA |
| C. | A-DNA |
| D. | Quadraplex DNA |
| Answer» B. Z-DNA | |
| 14. |
Who described the structure of DNA double helix? |
| A. | Peter Mitchell |
| B. | Andre Jagendorf |
| C. | Ernest Uribe |
| D. | Watson and Crick |
| Answer» E. | |