MCQOPTIONS
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MCQOPTIONS
This section includes 349 Mcqs, each offering curated multiple-choice questions to sharpen your Lisp knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
How many types of piRNA have been discovered so far? |
| A. | 10000 |
| B. | 60000 |
| C. | 190 |
| D. | 1000 |
| Answer» C. 190 | |
| 2. |
Translation is the process of _____________________ |
| A. | mRNA synthesis |
| B. | tRNA synthesis |
| C. | protein synthesis |
| D. | nucleic acid synthesis |
| Answer» D. nucleic acid synthesis | |
| 3. |
At least how many complementary sequences must be present on mRNA for it to be bound by miRNA? |
| A. | 8 |
| B. | 1 |
| C. | 2 |
| D. | 20 |
| Answer» B. 1 | |
| 4. |
How many types of distinct ribosomal RNAs are present in eukaryotic ribosomes? |
| A. | 1 |
| B. | 2 |
| C. | 3 |
| D. | 4 |
| Answer» E. | |
| 5. |
What drives the conformational change in the ribosome? |
| A. | GTP hydrolysis |
| B. | AMP hydrolysis |
| C. | ATP hydrolysis |
| D. | GDP hydrolysis |
| Answer» B. AMP hydrolysis | |
| 6. |
Degradation of cellular unwanted proteins is carried out in _________ |
| A. | Proteasomes |
| B. | Lysosome |
| C. | Peroxisomes |
| D. | Ribosomes |
| Answer» B. Lysosome | |
| 7. |
Which of following describes passing of traits not controlled by DNA sequence itself? |
| A. | post transcriptional modifications |
| B. | epigenetic inheritance |
| C. | post translational modification |
| D. | operons |
| Answer» C. post translational modification | |
| 8. |
Deletion maps are used to determine sites in the genome which interact with ___________________ |
| A. | transcription factors |
| B. | polymerase |
| C. | ribonuclease |
| D. | endonuclease |
| Answer» B. polymerase | |
| 9. |
Ribonuclease P is involve in the processing of ___________________ |
| A. | sno RNA |
| B. | rRNA |
| C. | pre-tRNA |
| D. | pre-mRNA |
| Answer» D. pre-mRNA | |
| 10. |
When was the first base sequence of a transfer RNA reported? |
| A. | 1935 |
| B. | 1945 |
| C. | 1955 |
| D. | 1965 |
| Answer» E. | |
| 11. |
Importance of transcription factors in embryonic stem cells was demonstrated in ______________ |
| A. | 1990 |
| B. | 1994 |
| C. | 2000 |
| D. | 2006 |
| Answer» E. | |
| 12. |
Which enzyme unwinds the DNA? |
| A. | helicase |
| B. | topoisomerase |
| C. | nuclease |
| D. | endonuclease |
| Answer» B. topoisomerase | |
| 13. |
What are small scale mutations at DNA level called? |
| A. | point mutation |
| B. | translocation |
| C. | segment deletion |
| D. | splicing |
| Answer» B. translocation | |
| 14. |
Physical processes that give an organism its shape are called |
| A. | differentiation |
| B. | translation |
| C. | recombination |
| D. | metamorphosis |
| Answer» E. | |
| 15. |
The cry-of-the-cat syndrome is due to a defect in chromosome __________ |
| A. | 2 |
| B. | 4 |
| C. | 5 |
| D. | 9 |
| Answer» D. 9 | |
| 16. |
Each enhancer is composed of approximately how many control elements? |
| A. | 10 |
| B. | 20 |
| C. | 2 |
| D. | 50 |
| Answer» B. 20 | |
| 17. |
Attachment of which of following is not involved in gene regulation? |
| A. | methyl |
| B. | acetyl |
| C. | phosphate |
| D. | hydrogen |
| Answer» E. | |
| 18. |
In making of which of following does lens cell specialize? |
| A. | bile |
| B. | blood |
| C. | Crystallin |
| D. | albumin |
| Answer» D. albumin | |
| 19. |
Which of following is true for mRNA of Hemoglobin polypeptides? |
| A. | made only once |
| B. | unusually unstable |
| C. | slightly stable |
| D. | unusually stable |
| Answer» E. | |
| 20. |
Under minimal conditions, the cell has fewer than 5 copies of enzyme β-galactosidase. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 21. |
Which of following is generally thought to promote transcription by opening chromatin structure? |
| A. | DNA methylation |
| B. | histone methylation |
| C. | histone acetylation |
| D. | phosphate addition |
| Answer» D. phosphate addition | |
| 22. |
Which of the following moves in consecutive blocks of three nucleotides? |
| A. | ribosome |
| B. | ribozyme |
| C. | polymerase |
| D. | helicase |
| Answer» B. ribozyme | |
| 23. |
Which types of changes participate in the process of natural selection? |
| A. | nonsynonymous |
| B. | phenotypic |
| C. | allotypic |
| D. | synonymous |
| Answer» B. phenotypic | |
| 24. |
In what percentage of cancer do p53 mutations occur? |
| A. | 90 |
| B. | 40 |
| C. | 10 |
| D. | 50 |
| Answer» E. | |
| 25. |
Signal peptide is consists of how many amino acids? |
| A. | 10 |
| B. | 20 |
| C. | 30 |
| D. | 40 |
| Answer» C. 30 | |
| 26. |
Which of the following is a rare genetic disorder? |
| A. | Myeloma |
| B. | Meningitis |
| C. | Fanconi anemia |
| D. | Breast cancer |
| Answer» D. Breast cancer | |
| 27. |
Inversions can lead to a deletion or duplication in the chromosome. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 28. |
When was it first discovered that RNA molecules are capable of catalyzing chemical reactions? |
| A. | 1962 |
| B. | 1972 |
| C. | 1982 |
| D. | 1992 |
| Answer» D. 1992 | |
| 29. |
How many DNA nucleotides are exposed when once unwound? |
| A. | up to 20 |
| B. | up to 80 |
| C. | up to 100 |
| D. | up to 300 |
| Answer» B. up to 80 | |
| 30. |
Which of following generally turns off genes or is present on genes in cells where they are not expressed? |
| A. | DNA methylation |
| B. | histone acetylation |
| C. | phosphate addition |
| D. | histone methylation |
| Answer» B. histone acetylation | |
| 31. |
What is process of passing methylation patterns from parent to offspring's called? |
| A. | methyl regulation |
| B. | methyl formation |
| C. | methylation inheritance |
| D. | genomic imprinting |
| Answer» E. | |
| 32. |
Which of following proteins becomes functional only after a central part of it is cleaved during post-translational modification? |
| A. | kinase |
| B. | protease |
| C. | chaperon |
| D. | insulin |
| Answer» E. | |
| 33. |
Ultraviolet rays can act as a mutagen by affecting which of following? |
| A. | thymine dimers in DNA |
| B. | guanine dimers in DNA |
| C. | protein structure |
| D. | mRNA |
| Answer» B. guanine dimers in DNA | |
| 34. |
Transfer RNA linked to an amino acid is called _____________ |
| A. | a-tRNA |
| B. | amino-tRNA |
| C. | tRNA |
| D. | aa-tRNA |
| Answer» E. | |
| 35. |
To carry out translational-level control, miRNAs bind to __________ of their target mRNAs. |
| A. | 3’ |
| B. | 5’ |
| C. | intergenic sites |
| D. | exonuclease sites |
| Answer» B. 5’ | |
| 36. |
Segments of non-coding DNA that serve as binding sites for transcription factors are called |
| A. | control elements |
| B. | binding elements |
| C. | initiator complex |
| D. | transcription elements |
| Answer» B. binding elements | |
| 37. |
Sequence-specific transcription factors can act as transcriptional activators or repressors. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 38. |
Which type of control determines for how long will a particular mRNA be translated? |
| A. | Replication-level |
| B. | Translational-level |
| C. | Transcriptional-level |
| D. | Processing-level |
| Answer» C. Transcriptional-level | |
| 39. |
Chromatin immuno-precipitation is induced by _____________________ |
| A. | antigens |
| B. | antibodies |
| C. | anti-histamines |
| D. | anti-allergens |
| Answer» C. anti-histamines | |
| 40. |
How many changes must occur at DNA level for a cell to become fully cancerous? |
| A. | 1 |
| B. | 2 |
| C. | 100 |
| D. | 6 |
| Answer» E. | |
| 41. |
When were the first structures of ribosomal subunits made by scientists? |
| A. | 1980 |
| B. | 1990 |
| C. | 2000 |
| D. | 2010 |
| Answer» D. 2010 | |
| 42. |
Which of following is basic unit of structure? |
| A. | cells |
| B. | tissues |
| C. | organs |
| D. | systems |
| Answer» B. tissues | |
| 43. |
The first amino acid incorporated at the N-terminus of polypeptide is ___________________ |
| A. | methionine |
| B. | cysteine |
| C. | tryptophan |
| D. | valine |
| Answer» B. cysteine | |
| 44. |
Discrete functional and structural regions in proteins are called |
| A. | beads |
| B. | fingers |
| C. | motifs |
| D. | domains |
| Answer» E. | |
| 45. |
The studies that led to discovery of posttranscriptional gene silencing phenomena were performed on ____________ |
| A. | petunia |
| B. | sunflower |
| C. | maize |
| D. | wheat |
| Answer» B. sunflower | |
| 46. |
What is molecular weight in Daltons of p53 protein? |
| A. | 5300 |
| B. | 5.3 |
| C. | 53000 |
| D. | 53 |
| Answer» D. 53 | |
| 47. |
Drosophila egg is surrounded by which of following? |
| A. | albumin |
| B. | nurse cells |
| C. | yolk |
| D. | oocytes |
| Answer» C. yolk | |
| 48. |
Which of the following is a stop codon in mitochondrial mRNA? |
| A. | AUG |
| B. | UUU |
| C. | AGG |
| D. | UGA |
| Answer» D. UGA | |
| 49. |
A single gene can encode two or more related proteins by the process of _________________ |
| A. | gene silencing |
| B. | alternative splicing |
| C. | recombination |
| D. | transcription |
| Answer» C. recombination | |
| 50. |
Which organism was used for experiments that led to “one gene – one enzyme” hypothesis? |
| A. | Neurospora |
| B. | Nematode |
| C. | Mus musculus |
| D. | Drosophila |
| Answer» B. Nematode | |