MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
What is function of A site on ribosomes? |
| A. | exit site |
| B. | peptidyl tRNA binding site |
| C. | mRNA cutting complex |
| D. | aminoacyl-tRNA binding site |
| Answer» E. | |
| 2. |
Which of following is not coded by DNA? |
| A. | non coding RNAs |
| B. | sugars |
| C. | tRNA |
| D. | proteins |
| Answer» C. tRNA | |
| 3. |
Which was the first artificially synthesized polypeptide? |
| A. | polyphenylalanine |
| B. | tyrosine |
| C. | valine |
| D. | polyisoleucine |
| Answer» B. tyrosine | |
| 4. |
The repressor protein is encoded by _________________ |
| A. | regulatory gene |
| B. | structural gene |
| C. | transfer-DNA |
| D. | ribosomal-RNA |
| Answer» B. structural gene | |
| 5. |
Prader-Willi syndrome (PWS) is caused due to disturbances in which of the following chromosomes? |
| A. | 15 |
| B. | 16 |
| C. | 19 |
| D. | 21 |
| Answer» B. 16 | |
| 6. |
Which of following is an example of non-enzyme protein? |
| A. | keratin |
| B. | protease |
| C. | Tyrosinase |
| D. | kinase |
| Answer» B. protease | |
| 7. |
Mutations in which of the following genes lead to a rare form of muscular dystrophy? |
| A. | lamin |
| B. | tannin |
| C. | gerotonin |
| D. | rennin |
| Answer» B. tannin | |
| 8. |
Which of following is attached to a protein to mark it for degradation? |
| A. | cytosine |
| B. | adenine |
| C. | ubiquitin |
| D. | apoptotic proteins |
| Answer» D. apoptotic proteins | |
| 9. |
Trp repressor protein is a product of which of following types of genes? |
| A. | controlling |
| B. | regulatory |
| C. | stopping |
| D. | metabolic |
| Answer» C. stopping | |
| 10. |
The length of tRNA molecules is ________________ nucleotides. |
| A. | 20-30 |
| B. | 50-70 |
| C. | 73-93 |
| D. | 83-93 |
| Answer» D. 83-93 | |
| 11. |
Which of following proteins encode a specific transcription factor that promotes synthesis of cell cycle-inhibiting proteins? |
| A. | p53 |
| B. | ras |
| C. | jak |
| D. | stat |
| Answer» B. ras | |
| 12. |
Drosophila genes that control pattern formation in late embryo and subsequent stages are called |
| A. | growth factors |
| B. | ingen genes |
| C. | homeotic genes |
| D. | metamorphosis |
| Answer» D. metamorphosis | |
| 13. |
How much of mass of ribosomes are made of proteins? |
| A. | 1/3rd |
| B. | 1/5th |
| C. | 1/10th |
| D. | 1/4th |
| Answer» B. 1/5th | |
| 14. |
Which of following may change a normal codon to a stop codon? |
| A. | non sense mutation |
| B. | missense mutation |
| C. | point mutation |
| D. | substitution |
| Answer» B. missense mutation | |
| 15. |
The first RNAi therapeutics was aimed at treating ______________________ |
| A. | muscular dystrophy |
| B. | macular degeneration |
| C. | multiple myeloma |
| D. | neurodegeneration |
| Answer» C. multiple myeloma | |
| 16. |
Which of following is a start codon? |
| A. | AUG |
| B. | AGU |
| C. | UUU |
| D. | CCU |
| Answer» B. AGU | |
| 17. |
Which of following does not code for alanine? |
| A. | GCU |
| B. | GCA |
| C. | UGA |
| D. | GCC |
| Answer» D. GCC | |
| 18. |
A typical tRNA consists of approximately how many nucleotides? |
| A. | 100 |
| B. | 1000 |
| C. | 200 |
| D. | 80 |
| Answer» E. | |
| 19. |
Chaperone protein helps in which of following function? |
| A. | protein folding |
| B. | translation |
| C. | transcription |
| D. | replication |
| Answer» B. translation | |
| 20. |
What is stretch of DNA called which is downstream promoter and is transcribed into an mRNA? |
| A. | transcription site |
| B. | transcription unit |
| C. | RNA unit |
| D. | map unit |
| Answer» C. RNA unit | |
| 21. |
Which of following factors helps in termination of translation process? |
| A. | release factor |
| B. | stop factor |
| C. | termination factor |
| D. | initiating factor |
| Answer» B. stop factor | |
| 22. |
Which of following helps in correct matching of amino acid with tRNA? |
| A. | tRNA cutter |
| B. | codons |
| C. | aminoacyl-tRNA synthetases |
| D. | tRNA sequence |
| Answer» D. tRNA sequence | |
| 23. |
Flexible base pairing at codons is called |
| A. | wobble |
| B. | shuffle |
| C. | recombination |
| D. | flexibility |
| Answer» B. shuffle | |
| 24. |
Which of following is not a stage of transcription? |
| A. | initiation |
| B. | addition |
| C. | elongation |
| D. | termination |
| Answer» C. elongation | |
| 25. |
CAAT and GC box are ________________ |
| A. | stop codons |
| B. | promoter sequences |
| C. | inhibitor sequences |
| D. | operator sequences |
| Answer» C. inhibitor sequences | |
| 26. |
Production of multiple copies of a gene is called |
| A. | gene multiplication |
| B. | gene amplification |
| C. | gene unit |
| D. | differentiation |
| Answer» C. gene unit | |
| 27. |
Analogues of glucocorticoids are prescribed as ________________ agents. |
| A. | sedative |
| B. | anti-fertility |
| C. | anti-inflammatory |
| D. | anti-aging |
| Answer» D. anti-aging | |
| 28. |
Regulatory protein CAP is an abbreviation for |
| A. | catabolite amplifying protein |
| B. | cyclic activator protein |
| C. | catabolite activator protein |
| D. | carrier activator protein |
| Answer» D. carrier activator protein | |
| 29. |
Messenger RNAs are found in the ________________ |
| A. | nucleus |
| B. | cytoplasm |
| C. | nucleolus |
| D. | lysosome |
| Answer» C. nucleolus | |
| 30. |
RNA editing is particularly important in the ________________ |
| A. | digestive system |
| B. | reproductive system |
| C. | nervous system |
| D. | circulatory system |
| Answer» D. circulatory system | |
| 31. |
P53 activates which of following genes that halts cell cycle temporarily? |
| A. | p39 |
| B. | p29 |
| C. | p19 |
| D. | p21 |
| Answer» E. | |
| 32. |
What does miRNA stand for? |
| A. | micro RNA |
| B. | mini RNA |
| C. | messenger RNA |
| D. | mega rRNA |
| Answer» B. mini RNA | |
| 33. |
A change in nucleotide sequence that does not affect the amino acid sequence is called _____________ change. |
| A. | insignificant |
| B. | significant |
| C. | synonymous |
| D. | nonsynonymous |
| Answer» D. nonsynonymous | |
| 34. |
Initial mRNA that has not yet been translated to a protein is called |
| A. | initial transcript |
| B. | new RNA |
| C. | primary transcript |
| D. | naive rRNA |
| Answer» D. naive rRNA | |
| 35. |
When was the link between enzymes and inherited disease first elucidated? |
| A. | 1708 |
| B. | 1808 |
| C. | 1908 |
| D. | 2008 |
| Answer» D. 2008 | |
| 36. |
The chromosomal aberrations follow _____________________ |
| A. | chromosomal breakage |
| B. | meiosis |
| C. | mitosis |
| D. | necrosis |
| Answer» B. meiosis | |
| 37. |
What is size of eukaryotic ribosomes compared to prokaryotic ribosomes? |
| A. | slightly larger |
| B. | slightly smaller |
| C. | significantly larger |
| D. | same size |
| Answer» B. slightly smaller | |
| 38. |
All mature tRNAs have the sequence CCA at their 3’ end. |
| A. | True |
| B. | False |
| C. | May be True or False |
| D. | Can't say |
| Answer» B. False | |
| 39. |
Start codon codes for which of following amino acids? |
| A. | Lysine |
| B. | Proline |
| C. | Alanine |
| D. | Methionine |
| Answer» E. | |
| 40. |
The enzyme aminoacyl-tRNA synthetase is responsible for linking ____________________________ |
| A. | amino acid to tRNA |
| B. | amino acid to mRNA |
| C. | carboxyl to tRNA |
| D. | carboxyl to mRNA |
| Answer» B. amino acid to mRNA | |
| 41. |
Which of following contribute to large scale mutations? |
| A. | deletion of parts of DNA |
| B. | DNA sequence |
| C. | protein sequence |
| D. | chromosomal rearrangements |
| Answer» E. | |
| 42. |
Which is a DNA-binding protein? |
| A. | repressor |
| B. | operator |
| C. | luciferase |
| D. | thymidine |
| Answer» B. operator | |
| 43. |
What is tRNA molecule called when it is attached to a complementary amino acid? |
| A. | activated tRNA |
| B. | charged tRNA |
| C. | bonded tRNA |
| D. | naive tRNA |
| Answer» C. bonded tRNA | |
| 44. |
Which of following enzymes is involved in synthesis of mRNA from DNA? |
| A. | RNA polymerase |
| B. | helicase |
| C. | DNA polymerase i |
| D. | DNA polymerase ii |
| Answer» B. helicase | |
| 45. |
What are multiple ribosomes attached to an mRNA called? |
| A. | Polysomes |
| B. | Multisomes |
| C. | ribosomal complex |
| D. | ribozymes |
| Answer» B. Multisomes | |
| 46. |
Energy required for synthesis of a polypeptide chain in a ribosome is provided by |
| A. | GTP |
| B. | Adenosine triphosphate (ATP) |
| C. | GDP |
| D. | ADP |
| Answer» B. Adenosine triphosphate (ATP) | |
| 47. |
Coding or expressing sequences in pre mRNA transcript is called |
| A. | coding sites |
| B. | splice sites |
| C. | introns |
| D. | exons |
| Answer» E. | |
| 48. |
Which of following has a cloverleaf structure? |
| A. | tRNA |
| B. | mRNA |
| C. | rRNA |
| D. | protein |
| Answer» B. mRNA | |
| 49. |
RNA molecules that function as enzymes are called |
| A. | RNAse |
| B. | RNA cutter |
| C. | ribozymes |
| D. | spliceosome |
| Answer» D. spliceosome | |
| 50. |
How many total codons are there that code for proteins? |
| A. | 19 |
| B. | 64 |
| C. | 26 |
| D. | 89 |
| Answer» C. 26 | |