 
			 
			MCQOPTIONS
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				This section includes 13 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | The expression of the tryptophan operon is independent of the availability of tryptophan in culture media. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 2. | Which of the following is true about tryptophan operon? | 
| A. | Tetramer of identical subunits | 
| B. | The RNA product is very stable | 
| C. | The Trp repressor binds to the tryptophan | 
| D. | The Trp repressor is the product of the Trp operon | 
| Answer» D. The Trp repressor is the product of the Trp operon | |
| 3. | Tryptophan operon in E. coli is a repressible operon. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 4. | The lac operon is regulated by cAMP by ___________ | 
| A. | Binding to lac repressor | 
| B. | Binding to operator | 
| C. | Binding to promoter | 
| D. | Binding to catabolite activator protein | 
| Answer» E. | |
| 5. | Glucose, as the carbon source, is the first choice by bacteria even if other sugars are available. The mechanism behind this selectivity is ___________ | 
| A. | Operon repression | 
| B. | Glucose utilization | 
| C. | Enzyme repression | 
| D. | Catabolite repression | 
| Answer» E. | |
| 6. | Which of the following is not present in the -galactosidase structural gene and thus is not transcribed by the same promoter? | 
| A. | Lac A | 
| B. | Lac I | 
| C. | Lac Z | 
| D. | Lac Y | 
| Answer» C. Lac Z | |
| 7. | Choose the correct pair among the following. | 
| A. | The DNA sequence to which stigma factor binds enhancer | 
| B. | The DNA sequence to which RNA polymerase binds operator | 
| C. | The DNA sequence that codes for a protein structural gene | 
| D. | The DNA sequence to which repressors binds promoter | 
| Answer» D. The DNA sequence to which repressors binds promoter | |
| 8. | Operons are ___________ | 
| A. | of approximately uniform size | 
| B. | found in some eukaryotes | 
| C. | not able to bind to proteins | 
| D. | smaller in lower eukaryotes and longer in higher eukaryotes | 
| Answer» C. not able to bind to proteins | |
| 9. | Which of the following is not an example of allosteric regulation? | 
| A. | Inactivation of nitrogenase by ADP ribosylation | 
| B. | Catabolite repression by CAP in E. coli | 
| C. | Regulation of phosphofructokinase activity | 
| D. | Regulation of lac operon by allolactose | 
| Answer» B. Catabolite repression by CAP in E. coli | |
| 10. | The proteins of which of the following genes are regularly needed for cellular activity? | 
| A. | Regular genes | 
| B. | Smart genes | 
| C. | Structural genes | 
| D. | Housekeeping genes | 
| Answer» E. | |
| 11. | Recruitment of RNA polymerase to the promoter is a ___________ | 
| A. | Covalent binding | 
| B. | Cooperative binding | 
| C. | Protein-protein interaction | 
| D. | Van der Waals forces | 
| Answer» C. Protein-protein interaction | |
| 12. | The site where repressor binds the DNA is the ______________ | 
| A. | Promoter | 
| B. | Terminator | 
| C. | Operator | 
| D. | ORF | 
| Answer» D. ORF | |
| 13. | In case of transcription which is the rate limiting step? | 
| A. | Binding of RNA polymerase | 
| B. | Unwinding of DNA duplex | 
| C. | Promoter escape | 
| D. | Formation of the open complex | 
| Answer» B. Unwinding of DNA duplex | |