Explore topic-wise MCQs in Molecular Biology.

This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.

1.

How many subunits of Spo11 are involved in the process of cleavage of DNA?

A. 1
B. 2
C. 3
D. 4
Answer» C. 3
2.

What is the function of the Spo11 in meiotic recombination?

A. Introduction of mutation
B. Introduction of nick
C. Introduction of DSB
D. Introduction of lesion
Answer» D. Introduction of lesion
3.

What are homologs?

A. Part of DNA
B. Pair of nucleus
C. Pair of chromosomes
D. Part of a cell
Answer» D. Part of a cell
4.

For which biological phenomenon homologous recombination is critical?

A. Mitosis
B. Meiosis
C. Fragmentation
D. Sporing
Answer» C. Fragmentation
5.

What is non-disjunction?

A. Proper alignment
B. Sister chromatid formation
C. Failed alignment
D. Chromosome segregation
Answer» D. Chromosome segregation
6.

How many cycles are required for the configuration of chromosomes?

A. 1
B. 2
C. 3
D. 4
Answer» C. 3
7.

Processing of the DNA at the break site occurs at the 3 end.

A. True
B. False
Answer» C.
8.

What are the components of the MRX protein?

A. MreII, Rad50, Xrs2
B. Rad51, Rad52, Rad59
C. RecA, RuvC, RuvAB
D. Rad51C, WRN, BLH
Answer» B. Rad51, Rad52, Rad59
9.

What is the source of energy during the action of SPO11?

A. Cleavage of peptide bond
B. Cleavage of amide bond
C. Cleavage of glycoside bond
D. Cleavage of phosphodiester bond
Answer» E.
10.

What is the cleavage site of RuvC?

A. 5 .A/TTTG/C .3
B. 5 .G/TTTC/T .3
C. 5 .T/TGCG/C .3
D. 5 .C/ATTG/T .3
Answer» B. 5 .G/TTTC/T .3
11.

After cleaved by RuvC the resulting ligated recombination products will only be the splice product.

A. True
B. False
Answer» C.
12.

Which component cleaves the specific DNA strands at the Holliday junction?

A. RuvC
B. RuvD
C. RuvA
D. RuvB
Answer» B. RuvD
13.

The RuvAB complex specifically recognizes the Holliday junction in an ATP dependent manner.

A. True
B. False
Answer» B. False
14.

What is the joint molecule?

A. RecB of the RecBCD pathway
B. B DNA
C. Z DNA
D. Rec A bound three stranded structure
Answer» E.
15.

What is the central protein of homologous recombination?

A. RecB
B. RecD
C. RecA
D. RecC
Answer» D. RecC