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This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
1. |
How many subunits of Spo11 are involved in the process of cleavage of DNA? |
A. | 1 |
B. | 2 |
C. | 3 |
D. | 4 |
Answer» C. 3 | |
2. |
What is the function of the Spo11 in meiotic recombination? |
A. | Introduction of mutation |
B. | Introduction of nick |
C. | Introduction of DSB |
D. | Introduction of lesion |
Answer» D. Introduction of lesion | |
3. |
What are homologs? |
A. | Part of DNA |
B. | Pair of nucleus |
C. | Pair of chromosomes |
D. | Part of a cell |
Answer» D. Part of a cell | |
4. |
For which biological phenomenon homologous recombination is critical? |
A. | Mitosis |
B. | Meiosis |
C. | Fragmentation |
D. | Sporing |
Answer» C. Fragmentation | |
5. |
What is non-disjunction? |
A. | Proper alignment |
B. | Sister chromatid formation |
C. | Failed alignment |
D. | Chromosome segregation |
Answer» D. Chromosome segregation | |
6. |
How many cycles are required for the configuration of chromosomes? |
A. | 1 |
B. | 2 |
C. | 3 |
D. | 4 |
Answer» C. 3 | |
7. |
Processing of the DNA at the break site occurs at the 3 end. |
A. | True |
B. | False |
Answer» C. | |
8. |
What are the components of the MRX protein? |
A. | MreII, Rad50, Xrs2 |
B. | Rad51, Rad52, Rad59 |
C. | RecA, RuvC, RuvAB |
D. | Rad51C, WRN, BLH |
Answer» B. Rad51, Rad52, Rad59 | |
9. |
What is the source of energy during the action of SPO11? |
A. | Cleavage of peptide bond |
B. | Cleavage of amide bond |
C. | Cleavage of glycoside bond |
D. | Cleavage of phosphodiester bond |
Answer» E. | |
10. |
What is the cleavage site of RuvC? |
A. | 5 .A/TTTG/C .3 |
B. | 5 .G/TTTC/T .3 |
C. | 5 .T/TGCG/C .3 |
D. | 5 .C/ATTG/T .3 |
Answer» B. 5 .G/TTTC/T .3 | |
11. |
After cleaved by RuvC the resulting ligated recombination products will only be the splice product. |
A. | True |
B. | False |
Answer» C. | |
12. |
Which component cleaves the specific DNA strands at the Holliday junction? |
A. | RuvC |
B. | RuvD |
C. | RuvA |
D. | RuvB |
Answer» B. RuvD | |
13. |
The RuvAB complex specifically recognizes the Holliday junction in an ATP dependent manner. |
A. | True |
B. | False |
Answer» B. False | |
14. |
What is the joint molecule? |
A. | RecB of the RecBCD pathway |
B. | B DNA |
C. | Z DNA |
D. | Rec A bound three stranded structure |
Answer» E. | |
15. |
What is the central protein of homologous recombination? |
A. | RecB |
B. | RecD |
C. | RecA |
D. | RecC |
Answer» D. RecC | |