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This section includes 36 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
1. |
The pathway of a tRNA during polypeptide elongation on the ribosome is |
A. | A site → P site → E site |
B. | P site → entry site → exit site |
C. | A site → P site → entry site |
D. | P site → A site → E site |
Answer» B. P site → entry site → exit site | |
2. |
Degenerated codon differs mostly in |
A. | the identities of their second base |
B. | the identities of their third base |
C. | the wobble position |
D. | both (b) and (c) |
Answer» E. | |
3. |
Which of the following has unusual bases? |
A. | mRNA |
B. | tRNA |
C. | rRNA |
D. | hnRNA |
Answer» C. rRNA | |
4. |
The site on a bacterial chromosome that marks the termination point for chromosome replication is called |
A. | ter |
B. | a stop codon. |
C. | a stem-loop |
D. | pau |
Answer» B. a stop codon. | |
5. |
Which of the following inhibits initiation at higher concentrations? |
A. | Chloramphenicol |
B. | Streptomycin |
C. | Diphtheria toxin |
D. | Ricin |
Answer» C. Diphtheria toxin | |
6. |
Which of the following catalyzes ADP-ribosylation of a diphthamide residue? |
A. | Chloramphenicol |
B. | Cycloheximide |
C. | Diphtheria toxin |
D. | Ricin |
Answer» D. Ricin | |
7. |
The eukaryotic mRNA binding to the ribosomes is facilitated by ____________ |
A. | T-RNA |
B. | Poly-A tail |
C. | Shine Dalgarno sequence |
D. | 7-methyl guanosine cap |
Answer» E. | |
8. |
What is the role of small nuclear RNAs in protein synthesis? |
A. | It translates genetic code to a specific amino acid |
B. | It modifies mRNA molecules prior to protein synthesis |
C. | It provides a genetic blueprint for the protein |
D. | It catalyzes the process |
Answer» C. It provides a genetic blueprint for the protein | |
9. |
What is the role of mRNA in protein synthesis? |
A. | It translates genetic code to a specific amino acid |
B. | It modifies mRNA molecules prior to protein synthesis |
C. | It provides a genetic blueprint for the protein |
D. | It catalyzes the process |
Answer» D. It catalyzes the process | |
10. |
Bacteria have ____________ |
A. | 70S ribosomes |
B. | 60S ribosomes |
C. | 50S ribosomes |
D. | 80S ribosomes |
Answer» B. 60S ribosomes | |
11. |
Which of the following inhibitor block translation in eukaryotes? |
A. | Cyclohexamine |
B. | Tetracycline |
C. | Puromycin |
D. | Streptomycin |
Answer» B. Tetracycline | |
12. |
Name the inhibitor which blocks translation in both prokaryotes as well as eukaryotes? |
A. | Chlorophenicol |
B. | Tetracycline |
C. | Puromycin |
D. | Streptomycin |
Answer» D. Streptomycin | |
13. |
Which of the following recognize a specific amino acid and its cognate t-RNA molecule? |
A. | t-RNA synthetase |
B. | Ribososme |
C. | r-RNA |
D. | Topoisomerase |
Answer» B. Ribososme | |
14. |
Who explained the wobble hypothesis? |
A. | Darwin |
B. | Watson and Crick |
C. | Samuel B. Weiss |
D. | Nirenberg |
Answer» C. Samuel B. Weiss | |
15. |
WHICH_OF_THE_FOLLOWING_RECOGNIZE_A_SPECIFIC_AMINO_ACID_AND_ITS_COGNATE_T-RNA_MOLECULE??$ |
A. | t-RNA synthetase |
B. | Ribososme |
C. | r-RNA |
D. | Topoisomerase |
Answer» B. Ribososme | |
16. |
WHICH_OF_THE_FOLLOWING_CATALYZES_ADP-RIBOSYLATION_OF_A_DIPHTHAMIDE_RESIDUE??$ |
A. | Chloramphenicol |
B. | Cycloheximide |
C. | Diphtheria toxin |
D. | Ricin |
Answer» D. Ricin | |
17. |
WHO_EXPLAINED_THE_WOBBLE_HYPOTHESIS??$ |
A. | Darwin |
B. | Watson and Crick |
C. | Samuel B. Weiss |
D. | Nirenberg |
Answer» C. Samuel B. Weiss | |
18. |
Which of the following inhibitor block translation in eukaryotes?$ |
A. | Cyclohexamine |
B. | Tetracycline |
C. | Puromycin |
D. | Streptomycin |
Answer» B. Tetracycline | |
19. |
Name the inhibitor which blocks translation in both prokaryotes as well as eukaryotes?$ |
A. | Chlorophenicol |
B. | Tetracycline |
C. | Puromycin |
D. | Streptomycin |
Answer» D. Streptomycin | |
20. |
Which of the following inhibits initiation at higher concentrations?$ |
A. | Chloramphenicol |
B. | Streptomycin |
C. | Diphtheria toxin |
D. | Ricin |
Answer» C. Diphtheria toxin | |
21. |
Name the drug which inhibits the initiation step of translation. |
A. | Cyclohexamine |
B. | Tetracycline |
C. | Ricin |
D. | Streptomycin |
Answer» E. | |
22. |
Which of the following blocks the peptidyl transferase of 80S eukaryotic ribosomes? |
A. | Chloramphenicol |
B. | Cycloheximide |
C. | Diphtheria toxin |
D. | Ricin |
Answer» C. Diphtheria toxin | |
23. |
Which of the following is not true to the nature of the genetic code? |
A. | Codon is triplet |
B. | Codons are commaless |
C. | Codons are overlapping |
D. | Codons are universal |
Answer» D. Codons are universal | |
24. |
The eukaryotic mRNA binding to the ribosomes is facilitated by |
A. | T-RNA |
B. | Poly-A tail |
C. | Shine Dalgarno sequence |
D. | 7-methyl guanosine cap |
Answer» E. | |
25. |
Mark the one, which is NOT a stop codon? |
A. | UAA |
B. | UAG |
C. | UGA |
D. | GGA |
Answer» E. | |
26. |
The role of small nuclear RNAs in protein synthesis is |
A. | It translates genetic code to a specific amino acid |
B. | It modifies mRNA molecules prior to protein synthesis |
C. | It provides genetic blueprint for the protein |
D. | It catalyzes the process |
Answer» C. It provides genetic blueprint for the protein | |
27. |
Which of the following is considered as a start codon? |
A. | AUG |
B. | GUG |
C. | UAG |
D. | AGG |
Answer» B. GUG | |
28. |
The role of mRNA in protein synthesis is |
A. | It translates genetic code to a specific amino acid |
B. | It modifies mRNA molecules prior to protein synthesis |
C. | It provides genetic blueprint for the protein |
D. | It catalyzes the process |
Answer» D. It catalyzes the process | |
29. |
Name the sequence of RNA, which is recognized by a small subunit of the ribosome. |
A. | Rho utilization site |
B. | Downstream sequence |
C. | Upstream sequence |
D. | Shine Dalgarno sequence |
Answer» E. | |
30. |
In how many steps protein biosynthesis takes place? |
A. | 2 |
B. | 3 |
C. | 4 |
D. | 5 |
Answer» E. | |
31. |
What is the size of the prokaryotic ribosome? |
A. | 80S |
B. | 70S |
C. | 40S |
D. | 60S |
Answer» C. 40S | |
32. |
Which is the third elongation step in bacteria? |
A. | Peptide bond formation |
B. | Binding of an incoming aminoacyl t-RNA |
C. | Translocation |
D. | None |
Answer» D. None | |
33. |
The following set of RNA is required in the translation process except one, mark the INCORRECT? |
A. | Si RNA |
B. | rRNA |
C. | mRNA |
D. | tRNA |
Answer» B. rRNA | |
34. |
Which of the following inactivates the 60S subunit of eukaryotic ribosomes? |
A. | Chloramphenicol |
B. | Cycloheximide |
C. | Diphtheria toxin |
D. | Ricin |
Answer» E. | |
35. |
tRNA has peptidal transferase activity. |
A. | True |
B. | False |
Answer» C. | |
36. |
Conversion of messages carried by mRNA into amino acid sequences is called___________ |
A. | Replication |
B. | DNA repair |
C. | Translation |
D. | Transcription |
Answer» D. Transcription | |