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This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
1. |
Which of the following is true about ribonucease? |
A. | Native state which is catalytically inactive is denatured |
B. | Unfolded state is inactive |
C. | Renatured ribonuclease is inactive |
D. | Renaturation involves reestablishment of the correct disulfide cross links |
Answer» B. Unfolded state is inactive | |
2. |
Protein A will fold into its native state only when protein B is also present in the solution. However, protein B can fold itself into native confirmation without the presence of protein A. Which of the following is true? |
A. | Protein B serves as precursor for protein A |
B. | Protein B serves as molecular chaperon for protein A |
C. | Protein B serves as ligand for protein A |
D. | Protein B serves as structural motif for protein A |
Answer» C. Protein B serves as ligand for protein A | |
3. |
Process of folding does not depend on ____________ |
A. | Concentration of salts |
B. | pH |
C. | Solute |
D. | Solvent |
Answer» D. Solvent | |
4. |
A process by which a protein structure assumes its functional shape or conformation is? |
A. | Denaturing |
B. | Folding |
C. | Synthesis |
D. | Hydrolysis |
Answer» C. Synthesis | |
5. |
WHICH_OF_THE_FOLLOWING_IS_TRUE_ABOUT_RIBONUCEASE??$ |
A. | Native state which is catalytically inactive is denatured |
B. | Unfolded state is inactive |
C. | Renatured ribonuclease is inactive |
D. | Renaturation involves reestablishment of the correct disulfide cross links |
Answer» B. Unfolded state is inactive | |
6. |
PROTEIN_A_WILL_FOLD_INTO_ITS_NATIVE_STATE_ONLY_WHEN_PROTEIN_B_IS_ALSO_PRESENT_IN_THE_SOLUTION._HOWEVER_PROTEIN_B_CAN_FOLD_ITSELF_INTO_NATIVE_CONFIRMATION_WITHOUT_THE_PRESENCE_OF_PROTEIN_A._WHICH_OF_THE_FOLLOWING_IS_TRUE??$ |
A. | Protein B serves as precursor for protein A |
B. | Protein B serves as molecular chaperon for protein A |
C. | Protein B serves as ligand for protein A |
D. | Protein B serves as structural motif for protein A |
Answer» C. Protein B serves as ligand for protein A | |
7. |
Which of the following about spontaneous folding is false? |
A. | It involves initial formation of highly compact structure |
B. | It involves initial formation of a local secondary structure |
C. | It is essentially a random process |
D. | It may be defective in some human diseases |
Answer» D. It may be defective in some human diseases | |
8. |
Which of the following are chaperons in E.coli? |
A. | Hsp70 |
B. | Hsp40 |
C. | DnaA |
D. | DnaK and DnaJ |
Answer» E. | |
9. |
As folding progresses which of the following does not take place? |
A. | Entropy decreases |
B. | Amount of protein in native state increases |
C. | Free energy increases |
D. | Amount of protein in native state decreases |
Answer» E. | |
10. |
Which of the following is a function of chaperone protein? |
A. | It degrades proteins that have folded improperly |
B. | It provide a template for how the proteins should fold |
C. | It rescues proteins that have folded improperly and allows them to refold properly |
D. | It degrades proteins that have folded properly |
Answer» D. It degrades proteins that have folded properly | |
11. |
Which of the following cannot denature a protein? |
A. | Iodoacetic acid |
B. | SDS detergent |
C. | Urea |
D. | Heating to 90°C |
Answer» B. SDS detergent | |
12. |
Process of folding does not depend on |
A. | Concentration of salts |
B. | pH |
C. | Solute |
D. | Solvent |
Answer» D. Solvent | |
13. |
A process by which a protein structure assumes its functional shape or conformation is |
A. | Denaturing |
B. | Folding |
C. | Synthesis |
D. | Hydrolysis |
Answer» C. Synthesis | |
14. |
Which of the following forces is favorable for protein folding? |
A. | Hydrophobic interactions |
B. | Hydrogen bonding |
C. | Vander Waals forces |
D. | Ionic bonding |
Answer» B. Hydrogen bonding | |