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This section includes 199 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
51. |
The deficiency of which of the following enzyme leads to galactosemia? |
A. | Galactokinase |
B. | Pyruvate kinase |
C. | PFK-1 |
D. | PFK-2 |
Answer» B. Pyruvate kinase | |
52. |
Which out of the following is not a flavoprotein? |
A. | Succinate dehydrogenase |
B. | Cytochrome c |
C. | Xanthine oxidase |
D. | NADH dehydrogenase-Qreductase |
Answer» C. Xanthine oxidase | |
53. |
What is the main source of natural fluoride? |
A. | Mushrooms |
B. | Potatoes |
C. | Meat |
D. | Water |
Answer» E. | |
54. |
Which of the following mineral is involved in protein metabolism and oxidation reactions? |
A. | Molybdenum |
B. | Manganese |
C. | Magnesium |
D. | calcium |
Answer» B. Manganese | |
55. |
One of the following statements is correct about pentose phosphate pathway |
A. | It generates 6 moles of CO₂ for each mole of glucose consumed |
B. | It generates 38 mol of ATP per mole of glucose consumed |
C. | It is a reductive pathway that consumes NADH |
D. | Present in plants but not in animals |
Answer» B. It generates 38 mol of ATP per mole of glucose consumed | |
56. |
Which of the following statements about the control of glycogen synthesis from blood glucose in myocytes is incorrect? |
A. | Insulin affects three of five steps in this pathway |
B. | The effects on transport and hexokinase activity increase the flux towards glycogen |
C. | The change in glycogen synthase activity increases the flux towards glycogen |
D. | Hexokinase enzyme is involved |
Answer» D. Hexokinase enzyme is involved | |
57. |
Iodine is a part of thyroid hormone and is essential for the prevention of |
A. | goiter |
B. | osteoporosis |
C. | muscle weakness |
D. | diarrhea |
Answer» B. osteoporosis | |
58. |
Which of the following statements is true about the control of muscle glycogen phosphorylase? |
A. | It is activated by phosphorylation by an active phosphorylase kinase |
B. | It is allosterically activated by ATP |
C. | It is allosterically activated by cAMP |
D. | Normally it exists in active form |
Answer» B. It is allosterically activated by ATP | |
59. |
Which of the following enzyme’s gene expression is slowed by insulin? |
A. | Hexokinase II |
B. | Hexokinase IV |
C. | PEP carboxykinase |
D. | Pyruvate kinase |
Answer» D. Pyruvate kinase | |
60. |
Selenium deficiency leads to |
A. | liver necrosis |
B. | diarrhea |
C. | multiple sclerosis |
D. | Crohn's disease |
Answer» B. diarrhea | |
61. |
∆G° is defined as the |
A. | Residual energy present in the reactants at equilibrium |
B. | Residual energy present in the products at equilibrium |
C. | Difference in the residual energy of reactants and products at equilibrium |
D. | Energy required in converting one mole of reactants to one mole of products |
Answer» E. | |
62. |
Which of the following is required as a component of blood hemoglobin? |
A. | Iron |
B. | Magnesium |
C. | Calcium |
D. | Copper |
Answer» B. Magnesium | |
63. |
Which is an example for chemical to osmotic energy conversion that occurs in living organisms? |
A. | ATP-driven muscle contraction |
B. | ATP-dependent photon emission in fireflies |
C. | light-induced electron flow in chloroplasts |
D. | ATP-driven active transport across a membrane |
Answer» E. | |
64. |
Ethanol is oxidized to acetaldehyde in the liver cytoplasm by |
A. | Alcohol dehydrogenase |
B. | Alcohol carboxylase |
C. | Pyruvate carboxylase |
D. | Pyruvate kinase |
Answer» B. Alcohol carboxylase | |
65. |
The mineral which aids in the utilization of iron and in hemoglobin synthesis is |
A. | calcium |
B. | phosphorus |
C. | cobalt |
D. | copper |
Answer» E. | |
66. |
The product formed in the isomerization of mannose 6-phosphate |
A. | Fructose 6-phosphate |
B. | Glucose 6-phosphate |
C. | 2-phosphoglycerate |
D. | 3-phosphoglycerate |
Answer» B. Glucose 6-phosphate | |
67. |
Which one out of the following enzymes acts in pentose phosphate pathway? |
A. | Aldolase |
B. | Glycogen phosphorylase |
C. | Pyruvate kinase |
D. | 6-phosphogluconate dehydrogenase |
Answer» E. | |
68. |
Which of the following mineral is involved in the enzyme -controlled energy yielding reactions of metabolism? |
A. | Calcium |
B. | Phosphorus |
C. | Iron |
D. | Copper |
Answer» C. Iron | |
69. |
Glucagon and epinephrine stimulate glycogen breakdown to glucose 6-phosphate |
A. | Directly by binding to glycogen phosphorylase |
B. | Indirectly by first stimulating adenylate cyclase to make cAMP |
C. | Only in the liver |
D. | Only in muscle cells |
Answer» C. Only in the liver | |
70. |
Which of the following is involved in pentose phosphate pathway? |
A. | Glucose 6-phosphate dehydrogenase |
B. | Acyl co-A glycerol transferases |
C. | PFK-2/FBPase-2 |
D. | Pyruvate dehydrogenase |
Answer» B. Acyl co-A glycerol transferases | |
71. |
When one molecule of glucose is oxidized to two molecules of lactate during anaerobic glycolysis, which of the following statements is false? |
A. | Glyceraldehyde 3-P dehydrogenase reaction produces 2 ATP molecules |
B. | Lactate dehydrogenase reaction produces no ATP |
C. | Pyruvate kinase reaction produces 2 ATP molecules |
D. | Phosphofructokinase-1 reaction uses 1 ATP molecule |
Answer» B. Lactate dehydrogenase reaction produces no ATP | |
72. |
Examples of goitrogenic foods are __________ and __________ . |
A. | turnips and corn |
B. | rutabagas and okra |
C. | raw cabbage and turnips |
D. | cassava and lettuce |
Answer» D. cassava and lettuce | |
73. |
Hydrolysis of lactose yields |
A. | D-galactose and D-glucose |
B. | D-glucose and D-glucose |
C. | D-galactose and D-fructose |
D. | D-fructose and D-glucose |
Answer» B. D-glucose and D-glucose | |
74. |
Glucose 6-phosphatase is present only in |
A. | Liver |
B. | Muscle |
C. | Epithelial tissues |
D. | Kidneys |
Answer» B. Muscle | |
75. |
Which of the following is true about the enzyme producing NADH from a triose phosphate in the glycolytic pathway? |
A. | It produces 1, 3-biphosphoglycerate and NADH |
B. | It catalyzes irreversible reaction |
C. | It uses NAD⁺ and dihydroxyacetone phosphate as substrates |
D. | It uses FADH₂ and glyceraldehyde 3-phosphate as substrates |
Answer» B. It catalyzes irreversible reaction | |
76. |
When blood sugar levels fall, glycolysis is halted in liver to allow _________ |
A. | Homeostasis |
B. | Anaerobic respiration |
C. | Aerobic respiration |
D. | Gluconeogenesis |
Answer» E. | |
77. |
Which of the following statements is correct about reductive pentose phosphate pathway? |
A. | It is not reversible |
B. | Transketolase transfers 3 carbon units |
C. | Transaldose transfers 2 carbon units |
D. | Pentoses can provide glycolytic intermediates |
Answer» E. | |
78. |
Which of the following type of metabolite is used for generating glucose under severe starvation conditions? |
A. | Amino acids |
B. | Fats |
C. | Glycogen |
D. | Starch |
Answer» B. Fats | |
79. |
Anabolism and catabolism are chemically linked in the form of |
A. | ADP |
B. | ATP |
C. | Phosphodiester linkage |
D. | ASP |
Answer» C. Phosphodiester linkage | |
80. |
Which of the following enzymes is involved in the positive regulation of glycolysis/gluconeogenesis? |
A. | Hexokinase II |
B. | Hexokinase IV |
C. | PFK-2/FBPase-2 |
D. | Pyruvate kinase |
Answer» D. Pyruvate kinase | |
81. |
A kinase is an enzyme that |
A. | removes phosphate groups of substrates |
B. | uses ATP to add a phosphate group to the substrate |
C. | uses NADH to change the oxidation state of the substrate |
D. | removes water from a double bond |
Answer» C. uses NADH to change the oxidation state of the substrate | |
82. |
During catabolism, only about 40% of the energy available from oxidizing glucose is used to synthesize ATP. Remaining 60% |
A. | is lost as heat |
B. | is used to reduce NADP |
C. | remains in the products of metabolism |
D. | is stored as fat. |
Answer» B. is used to reduce NADP | |
83. |
The released energy obtained by oxidation of glucose is stored as |
A. | a concentration gradient across a membrane |
B. | ADP |
C. | ATP |
D. | NAD+ |
Answer» D. NAD+ | |
84. |
Which trace mineral is a component of the enzyme that activates vitamin A in the eye? |
A. | Zinc |
B. | Iron |
C. | Iodine |
D. | Chromium |
Answer» B. Iron | |
85. |
Which of the following vitamin is essential for the absorption of calcium from the intestinal tract? |
A. | Vitamin D |
B. | Vitamin E |
C. | Vitamin B12 |
D. | Vitamin B6 |
Answer» B. Vitamin E | |
86. |
Which of the following enzyme catalyzes the first step of glycolysis? |
A. | Hexokinase |
B. | Pyruvate kinase |
C. | Glucokinase |
D. | Phosphofructokinase-1 |
Answer» B. Pyruvate kinase | |
87. |
The rate of breakdown of metabolites is termed as |
A. | Metabolic state |
B. | Metabolism |
C. | Steady state |
D. | Homeostasis |
Answer» D. Homeostasis | |
88. |
The substrate used in the last step of glycolysis is |
A. | Glyceraldehyde 3-phosphate |
B. | Pyruvate |
C. | Phosphoenolpyruvate |
D. | 1, 3-bisphosphoglycerate |
Answer» D. 1, 3-bisphosphoglycerate | |
89. |
Glycolytic pathway regulation involves |
A. | allosteric stimulation by ADP |
B. | allosteric inhibition by ATP |
C. | feedback, or product, inhibition by ATP |
D. | all of the above |
Answer» E. | |
90. |
Which of the following enzyme catalyses the direct transfer and incorporation of O₂ into a substrate molecule is |
A. | Reductase |
B. | Oxidase |
C. | Oxygenase |
D. | Peroxidase |
Answer» D. Peroxidase | |
91. |
What does first law of thermodynamics state? |
A. | Energy can neither be destroyed nor created |
B. | Energy cannot be 100 percent efficiently transformed from one type to another |
C. | All living organisms are composed of cells |
D. | Input of heat energy increases the rate of movement of atoms and molecules |
Answer» B. Energy cannot be 100 percent efficiently transformed from one type to another | |
92. |
Which One of the following statements about the control of enzyme activity by phosphorylation is correct |
A. | Phosphorylation of an enzyme results in conformational change |
B. | Phosphorylation of an enzyme occurs only at specific tyrosine residues |
C. | Phosphorylation of an enzyme is carried out by phosphoprotein phosphatases |
D. | Enzyme control by phosphorylation is irreversible |
Answer» B. Phosphorylation of an enzyme occurs only at specific tyrosine residues | |
93. |
Which of the following ion is required for the development of sound teeth with resistance to tooth decay? |
A. | Fluoride ion |
B. | Sodium ion |
C. | Chloride ion |
D. | Magnesium ion |
Answer» B. Sodium ion | |
94. |
Which of the following is necessary for the clotting of blood, functions of certain enzymes and control of fluids through cell membranes? |
A. | Calcium |
B. | Magnesium |
C. | Copper |
D. | Cobalt |
Answer» B. Magnesium | |
95. |
The enzyme which catalyzes the conversion of pyruvate to oxaloacetate |
A. | Pyruvate carboxylase |
B. | Pyruvate dehydrogenase |
C. | Pyruvate kinase |
D. | Phosphofructokinase-1 |
Answer» B. Pyruvate dehydrogenase | |
96. |
How many steps are catalyzed by different enzymes in glycolysis and gluconeogenesis? |
A. | 2 |
B. | 3 |
C. | 4 |
D. | 5 |
Answer» C. 4 | |
97. |
Which of the following statements is incorrect about oxidase? |
A. | They catalyze reactions involving hydrogen peroxide |
B. | They catalyze reaction using O₂ as a hydrogen acceptor |
C. | They catalyze reactions using niacin as coenzyme |
D. | They catalyze reactions of direct incorporation of O₂ into the substrate |
Answer» C. They catalyze reactions using niacin as coenzyme | |
98. |
Hydrolysis of sucrose yields |
A. | D-galactose and D-glucose |
B. | D-glucose and D-glucose |
C. | D-galactose and D-fructose |
D. | D-fructose and D-glucose |
Answer» E. | |
99. |
Conversion of xylulose 5-phosphate to ribulose 5-phosphate is catalyzed by |
A. | Phosphopentose epimerase |
B. | Transaldolase |
C. | Transketolase |
D. | Phosphopentose isomerase |
Answer» B. Transaldolase | |
100. |
Which of the following conversions is not catalyzed by hexokinase? |
A. | D-Glucose to glucose 6-phosphate |
B. | D-Fructose to fructose 6-phosphate |
C. | D-Mannose to mannose 6-phosphate |
D. | D-Fructose to fructose 1-phosphate |
Answer» E. | |