 
			 
			MCQOPTIONS
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				This section includes 21 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Consider a tandem repeat of the sequence GCU. Now if insertion of an A residue occurs in the message as follows What type of mutation has taken place in this case? | 
| A. | Missense mutation | 
| B. | Stop mutation | 
| C. | Frame shift mutation | 
| D. | Reverse mutation | 
| Answer» D. Reverse mutation | |
| 2. | Frame shift mutation can increase or decrease the length of a polypeptide. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 3. | Prenylation adds prenyl groups to the ___________ amino acid residues. | 
| A. | Methionine | 
| B. | Cystine | 
| C. | Threonine | 
| D. | Arginine | 
| Answer» C. Threonine | |
| 4. | How many types of modification are possible in eukaryotes by addition of lipids? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» E. | |
| 5. | Initiation of glycosylation occurs in the Golgi body. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 6. | In O-linked glycoproteins, the carbohydrates may be attached to how many amino acids? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» C. 3 | |
| 7. | In the N-linked glycoprotein, the carbohydrates are attached to which of the following bases? | 
| A. | Valine | 
| B. | Threonine | 
| C. | Asparagine | 
| D. | Serine | 
| Answer» D. Serine | |
| 8. | How many Proteolytic cleavages produce mature insulin? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» C. 3 | |
| 9. | INITIATION_OF_GLYCOSYLATION_OCCURS_IN_THE_GOLGI_BODY.?$ | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 10. | Prenylation adds prenyl groups to the ___________ amino acid residues.$ | 
| A. | Methionine | 
| B. | Cystine | 
| C. | Threonine | 
| D. | Arginine | 
| Answer» C. Threonine | |
| 11. | How_many_types_of_modification_are_possible_in_eukaryotes_by_addition_of_lipids?$ | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» E. | |
| 12. | If the insertions of three nucleotides occur in a consecutive manner it causes which of the following type of mutation? | 
| A. | Missense mutation | 
| B. | Stop mutation | 
| C. | Frame shift mutation | 
| D. | Reverse mutation | 
| Answer» D. Reverse mutation | |
| 13. | Frame_shift_mutation_can_increase_or_decrease_the_length_of_a_polypeptide. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 14. | In O-linked glycoproteins the carbohydrates may be attached to how many amino acids? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» C. 3 | |
| 15. | In the N-linked glycoprotein the carbohydrates are attached to which of the following bases? | 
| A. | Valine | 
| B. | Threonine | 
| C. | Asparagine | 
| D. | Serine | 
| Answer» D. Serine | |
| 16. | Glycosylation is the addition of ___________ to the protein. | 
| A. | Carbohydrate | 
| B. | Lipid | 
| C. | Fat | 
| D. | Minerals | 
| Answer» B. Lipid | |
| 17. | How many Proteolytic cleavages produce the mature insulin? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» C. 3 | |
| 18. | The first step in protein targeting is ___________ | 
| A. | Synthesis of protein | 
| B. | Translocation to Golgi body | 
| C. | Translocation to nucleus | 
| D. | Translocation to ER | 
| Answer» E. | |
| 19. | The amino acid is the signal sequence in any polypeptide chain for ____________ | 
| A. | Protein activity | 
| B. | Glycosylation site | 
| C. | Proteolytic site | 
| D. | Site for lipid addition | 
| Answer» D. Site for lipid addition | |
| 20. | Proteolytic modifications of the polypeptide are an important process in the mechanism for protein sorting and transport. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 21. | Which of the following is not a type of post translational modification? | 
| A. | Proteolysis | 
| B. | Protein folding | 
| C. | Glycosylation | 
| D. | Lipid addition | 
| Answer» C. Glycosylation | |