MCQOPTIONS
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MCQOPTIONS
This section includes 285 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine? |
| A. | The possession of a segmented RNA genome |
| B. | A limited number of capsule types |
| C. | The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings |
| D. | The ability of the Rotavirus to be transmitted faster |
| Answer» B. A limited number of capsule types | |
| 2. |
Which of the following is common in the disease caused by and ? |
| A. | Both organisms are gram-positive spore formers |
| B. | Diphtheria toxin and edema toxin are ADP ribosylating toxins |
| C. | The most serious disease symptoms are the direct result of toxin action |
| D. | Both organisms cause skin and respiratory tract infections |
| Answer» D. Both organisms cause skin and respiratory tract infections | |
| 3. |
Each of the 3 virulence factors of i.e. the capsule, edema toxin and lethal toxin can affect the activity of |
| A. | B cells |
| B. | macrophages |
| C. | ciliated epithelial cells |
| D. | M cells |
| Answer» C. ciliated epithelial cells | |
| 4. |
Both and |
| A. | are acquired by inhalation |
| B. | have cell walls that contain a high content of mycolic acids |
| C. | have polysaccharide capsules |
| D. | stay in the lung and rarely, if ever, enter the bloodstream |
| Answer» B. have cell walls that contain a high content of mycolic acids | |
| 5. |
Cholera toxin is an A-B type toxin in which the B portions bind to a receptor on a host cell and the A portion enters the cell to cause |
| A. | ADP ribosylation of adenylate cyclase that stops production of cAMP |
| B. | ADP ribosylation of a G protein that locks it into an active form that stimulates adenylate cyclase to make cAMP |
| C. | cleavage of rRNA that results in disruption of ribosome function |
| D. | ADP ribosylation of guanylate cyclase that stimulates production of cGMP |
| Answer» C. cleavage of rRNA that results in disruption of ribosome function | |
| 6. |
Plastic implants can pose a serious nosocomial infection problem because |
| A. | phagocytes have trouble moving on the plastic surface |
| B. | phagocytes have trouble engulfing bacteria embedded in a biofilm |
| C. | infected implants usually have to be surgically removed |
| D. | all of the above |
| Answer» E. | |
| 7. |
A major difference between EHEC and EPEC is |
| A. | EHEC secretes a Shiga-like toxin and EPEC does not |
| B. | EHEC possesses a type III secretion system and EPEC does not |
| C. | EPEC rearranges host cell actin and EHEC does not |
| D. | EPEC passes through the placenta to infect the fetus and EHEC does not |
| Answer» B. EHEC possesses a type III secretion system and EPEC does not | |
| 8. |
Which of the following is true regarding anthrax? |
| A. | Anthrax is caused by a virus |
| B. | Anthrax is highly contagious |
| C. | Inhalation anthrax and cutaneous anthrax are caused by separate strains of |
| D. | Inhalation Anthrax requires infection with a large number of spores |
| Answer» E. | |
| 9. |
Which of the following statements is not true regarding and/or the disease it causes? |
| A. | The pathogen contains mycolic acid in its cell wall |
| B. | The pathogen can live inside macrophages |
| C. | Antibodies to the pathogen are protective |
| D. | None of these |
| Answer» D. None of these | |
| 10. |
Type III secretion systems are used to inject "effector" proteins directly into a host cell. uses a type III secretion system to help the pathogen to |
| A. | survive the acid pH of the stomach |
| B. | secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine |
| C. | survive within macrophages |
| D. | activate T cells to proliferate and secrete cytokines |
| Answer» D. activate T cells to proliferate and secrete cytokines | |
| 11. |
The "A" subunit of diphtheria toxin |
| A. | binds host cell receptors found on heart cells |
| B. | cause ADP ribosylation of a factor involved in protein synthesis |
| C. | forms cAMP that leads to fluid accumulation |
| D. | lysis macrophages with the release of cytokines |
| Answer» C. forms cAMP that leads to fluid accumulation | |
| 12. |
Prontosil is |
| A. | an effective antibacterial when used in animals |
| B. | an effective antibacterial when used in in-vitro cultures |
| C. | an effective antibacterial both in animals as well as in in-vitro cultures |
| D. | not used as an antibacterial agent |
| Answer» D. not used as an antibacterial agent | |
| 13. |
The influenza vaccine is administered each year because |
| A. | mutations in the viral hemagglutinin may allow the virus to evade the immune response elicited by previous vaccines |
| B. | it is a polysaccharide vaccine that does not confer long-term protection |
| C. | the vaccine is sufficiently toxic to make it necessary to administer only a small amount at any one time |
| D. | none of the above |
| Answer» B. it is a polysaccharide vaccine that does not confer long-term protection | |
| 14. |
What is common in catheters and ventilators? |
| A. | They bypass important defenses of the body |
| B. | Bacteria responsible for associated infections are usually susceptible to antibiotics |
| C. | They predispose patients to viral rather than bacterial infections |
| D. | They are used primarily in neonatal intensive care units |
| Answer» B. Bacteria responsible for associated infections are usually susceptible to antibiotics | |
| 15. |
Alternative name for ' hepatocellular carcinoma' is |
| A. | Hepatocytes |
| B. | Lymphocytes |
| C. | Hepatoma |
| D. | Leukocytes |
| Answer» D. Leukocytes | |
| 16. |
Which of the following disease is an infection of the reticuloendothelial system? |
| A. | Cryptococcosis |
| B. | Moniliasis |
| C. | Histoplasmosis |
| D. | Coccidioidomycosis |
| Answer» D. Coccidioidomycosis | |
| 17. |
The organism causing whooping cough can grow on ordinary culture media. |
| A. | True |
| B. | False |
| C. | May be |
| D. | Can't say |
| Answer» C. May be | |
| 18. |
Puerperal fever is a streptococcal infection of the ______________ |
| A. | kidney |
| B. | skin |
| C. | uterus |
| D. | heart |
| Answer» D. heart | |
| 19. |
'CMV' is abbreviation of |
| A. | Cytomegalovirus |
| B. | Cauliflower virus |
| C. | Cow virus |
| D. | Influenza virus |
| Answer» B. Cauliflower virus | |
| 20. |
In children 'astrovirus' causes |
| A. | Skin infection |
| B. | Watery diarrhoea |
| C. | Vomiting |
| D. | Brain inflammation |
| Answer» C. Vomiting | |
| 21. |
Fungus diseases that occur on the nails, skin, hair are referred to as systemic mycoses. |
| A. | True |
| B. | False |
| C. | May be |
| D. | Can't say |
| Answer» C. May be | |
| 22. |
Which serovar of C. botulinum occurs mainly in the sediments of the Great Lakes? |
| A. | A |
| B. | B |
| C. | E |
| D. | F |
| Answer» D. F | |
| 23. |
Which of the following characteristic of the Rotavirus was important for the construction of the Rotashield vaccine? |
| A. | The possession of a segmented RNA genome |
| B. | A limited number of capsule types |
| C. | The ability of monkey Rotavirus strains to cause serious illness (diarrhea) in human beings |
| D. | The ability of the Rotavirus to be transmitted faster |
| Answer» B. A limited number of capsule types | |
| 24. |
Which drug is used for treatment of brucellosis in humans? |
| A. | Erythromycin |
| B. | Tetracycline |
| C. | Carbenicillin |
| D. | Gentamicin |
| Answer» C. Carbenicillin | |
| 25. |
What is the incubation period for kala azar disease? |
| A. | 24 h |
| B. | 1 month |
| C. | 2-4 months |
| D. | 7 days |
| Answer» D. 7 days | |
| 26. |
Kaposi's sarcoma is an opportunistic infection in 'AIDS' patient and is its causative agent in |
| A. | Human herpesvirus 8 |
| B. | Human papilloma virus |
| C. | Cytomegalovirus |
| D. | JC virus |
| Answer» B. Human papilloma virus | |
| 27. |
Type III secretion systems are used to inject "effector" proteins directly into a host cell. Salmonella uses a type III secretion system to help the pathogen to |
| A. | survive the acid pH of the stomach |
| B. | secrete LT (heat labile toxin) and ST (heat stable toxin) into the lumen of the intestine |
| C. | survive within macrophages |
| D. | activate T cells to proliferate and secrete cytokines |
| Answer» D. activate T cells to proliferate and secrete cytokines | |
| 28. |
Which among the following species causes tuberculosis? |
| A. | Mycobacterium leprae |
| B. | Mycobacterium kansasii |
| C. | Mycobacterium bovis |
| D. | Mycobacterium ulcerans |
| Answer» D. Mycobacterium ulcerans | |
| 29. |
Other than warts, some species of papilloma virus, may cause 'carcinoma' of the |
| A. | Lungs |
| B. | Vigina |
| C. | Cervix |
| D. | Urethra |
| Answer» D. Urethra | |
| 30. |
Which drug is used for treatment of anthrax? |
| A. | erythromycin |
| B. | penicillin |
| C. | tetracycline |
| D. | ampicillin |
| Answer» C. tetracycline | |
| 31. |
Coxsackie virus B3, a subgroup of enteroviruses, commonly causes |
| A. | acute hemorrhagic conjunctivitis |
| B. | muscular dystrophy |
| C. | myocarditis |
| D. | gastroenteritis |
| Answer» D. gastroenteritis | |
| 32. |
Which is not a major defense mechanism in the stomach? |
| A. | Proteolytic enzymes |
| B. | Low pH |
| C. | Dense normal flora |
| D. | All of these |
| Answer» D. All of these | |
| 33. |
Korean 'hemorrhagic' fever is caused by the |
| A. | Adenovirus |
| B. | Hantavirus |
| C. | Cache valley virus |
| D. | Chikungunya virus |
| Answer» C. Cache valley virus | |
| 34. |
Natural host for 'respiratory syncytial' virus is |
| A. | Pigs |
| B. | Human |
| C. | Goats |
| D. | Rats |
| Answer» C. Goats | |
| 35. |
Blastomyces brasiliensis causes which of the following disease? |
| A. | North American blastomycosis |
| B. | South American blastomycosis |
| C. | Histoplasmosis |
| D. | Sporotrichosis |
| Answer» C. Histoplasmosis | |
| 36. |
Complement- fixation is done for laboratory diagnosis of which of the following disease? |
| A. | Poliomyelitis |
| B. | Mumps |
| C. | Measles |
| D. | FMD |
| Answer» E. | |
| 37. |
Both Mycobacterium tuberculosis and Streptococcus pneumoniae |
| A. | are acquired by inhalation |
| B. | have cell walls that contain a high content of mycolic acids |
| C. | have polysaccharide capsules |
| D. | stay in the lung and rarely, if ever, enter the bloodstream |
| Answer» B. have cell walls that contain a high content of mycolic acids | |
| 38. |
'Astrovirus' is |
| A. | Nonenveloped RNA virus |
| B. | Enveloped RNA virus |
| C. | DNA virus |
| D. | Prion |
| Answer» B. Enveloped RNA virus | |
| 39. |
'Varicella-zoster' virus is transmitted by the |
| A. | Mouth |
| B. | Genital organs |
| C. | Respiratory droplets |
| D. | Aerosol |
| Answer» D. Aerosol | |
| 40. |
A disease that is characterized by ataxia, tremors and itching in sheep is known as |
| A. | Visna |
| B. | Scrapie |
| C. | Jackob disease |
| D. | Spongiform |
| Answer» C. Jackob disease | |
| 41. |
Way of transmission of 'arbovirus' is |
| A. | Cattles |
| B. | Monkeys |
| C. | Arthropods |
| D. | Pigs |
| Answer» D. Pigs | |
| 42. |
Size of 'togaviruses' is |
| A. | 80 nm |
| B. | 70 nm |
| C. | 35 nm |
| D. | 20 nm |
| Answer» C. 35 nm | |
| 43. |
Which drug is used for treatment of leishmaniasis? |
| A. | chloroquine phosphate |
| B. | metronidazole |
| C. | suramin |
| D. | sodium stibogluconate |
| Answer» E. | |
| 44. |
Which of the following is incorrect with respect to Paramyxoviruses? |
| A. | large (125 to 250 nm) |
| B. | core of single-stranded (—) RNA |
| C. | rna is segmented |
| D. | hemagglutinin and neuroaminidase activities occur together |
| Answer» D. hemagglutinin and neuroaminidase activities occur together | |
| 45. |
SV 40 causes diseases in which animal? |
| A. | monkeys |
| B. | rabbits |
| C. | humans |
| D. | cattle |
| Answer» B. rabbits | |
| 46. |
Croup in young children is caused by |
| A. | Parainfluenza virus |
| B. | Influenza B virus |
| C. | Influenza A virus |
| D. | Herpesvirus |
| Answer» B. Influenza B virus | |
| 47. |
Mucus helps in protecting against pathogens by |
| A. | lowering the pH |
| B. | facilitating the growth of normal flora |
| C. | blocking access and attachment of pathogens to mucosal surfaces |
| D. | sequestering Iron |
| Answer» D. sequestering Iron | |
| 48. |
Host for 'poliomyelitis' is limited to |
| A. | Reptiles |
| B. | Aves |
| C. | Primates |
| D. | Amphibians |
| Answer» D. Amphibians | |
| 49. |
Polyene antibiotics act on the plasma membrane of the fungus. |
| A. | True |
| B. | False |
| C. | May be |
| D. | Can't say |
| Answer» B. False | |
| 50. |
Which of the following toxins cause damage to the tissue cells by its phospholipase action? |
| A. | alpha toxin |
| B. | delta toxin |
| C. | protein A |
| D. | coagulase |
| Answer» C. protein A | |