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				This section includes 30 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | In the time since and diverged evolutionarily | 
| A. | there has been little change in either genome | 
| B. | has acquired many genes via horizontal transfer | 
| C. | has lost approximately 50% of its genome | 
| D. | none of these | 
| Answer» D. none of these | |
| 2. | Which of the following theory is supported by the genomic sequence of the obligate intracellular parasite ? | 
| A. | Parasitic bacteria have very large genomes | 
| B. | Parasites have a definite genomic sequence similar to viruses | 
| C. | Mitochondria have evolved from endosymbiotic bacteria | 
| D. | All bacteria evolved from viruses | 
| Answer» D. All bacteria evolved from viruses | |
| 3. | The physical nature of genomes is studied under | 
| A. | structural genomics | 
| B. | comparative genomics | 
| C. | proteo genomics | 
| D. | functional genomics | 
| Answer» B. comparative genomics | |
| 4. | Why the bacterium is difficult to culture? | 
| A. | Because it requires a great deal of water to reproduce | 
| B. | Because it is unable to use carbohydrates as an energy source | 
| C. | Because it lacks the genes needed for TCA cycle and oxidative phosphorylation | 
| D. | Because it requires extremely low temperature at which water freezes | 
| Answer» D. Because it requires extremely low temperature at which water freezes | |
| 5. | The flow of genetic material in microbial cells usually takes place from | 
| A. | RNA through DNA to proteins | 
| B. | proteins through RNA to DNA | 
| C. | DNA through RNA to proteins | 
| D. | none of these | 
| Answer» D. none of these | |
| 6. | Which of the following is used for determining the location of specific genes within the genome? | 
| A. | Genomics | 
| B. | Annotation | 
| C. | Cloning | 
| D. | Proteomics | 
| Answer» C. Cloning | |
| 7. | Proteomics is | 
| A. | the study of algal genomes | 
| B. | a branch of quantum physics dealing with proteins | 
| C. | the study of formation of lipo-protein in animals | 
| D. | the study of the entire collection of proteins expressed by an organism | 
| Answer» E. | |
| 8. | Which of the following is concerned with the management and analysis of biological data using computers? | 
| A. | Bio-physics | 
| B. | Bioinformatics | 
| C. | Genomics | 
| D. | Biomechanics | 
| Answer» C. Genomics | |
| 9. | Why is able to survive massive exposure to radiation? | 
| A. | Because it produces a thick shell which acts as a shield from the radiation | 
| B. | Because it has unique DNA repair mechanisms | 
| C. | Because its cellwall contains radioactive elements | 
| D. | Because it has many copies of genes encoding DNA repair | 
| Answer» E. | |
| 10. | What is the range of minimum set of genes required for life? | 
| A. | 50-100 genes | 
| B. | 250-350 genes | 
| C. | 1000-1500 genes | 
| D. | 1500-2000 genes | 
| Answer» C. 1000-1500 genes | |
| 11. | Which of the following is the study of the molecular organization of genomes, their information content and the gene products they encode? | 
| A. | Genetics | 
| B. | Ergonomics | 
| C. | Genomics | 
| D. | Bioinformatics | 
| Answer» D. Bioinformatics | |
| 12. | The word, used for the small solid supports onto which are spotted hundreds of thousands of tiny drops of DNA that can be used to screen gene expression, is | 
| A. | southern blot | 
| B. | cloning library | 
| C. | DNA microarrays | 
| D. | northern blot | 
| Answer» D. northern blot | |
| 13. | Which of the following organisms has the smallest genome? | 
| A. | None of these | 
| Answer» C. | |
| 14. | Studies of similarities and differences among the genomes of multiple organisms is carried out in | 
| A. | comparative genomics | 
| B. | proteomics | 
| C. | functional genomics | 
| D. | structural genomics | 
| Answer» B. proteomics | |
| 15. | Which type of genomics studies the transcripts and proteins expressed by a genome? | 
| A. | Comparative genomics | 
| B. | Structural genomics | 
| C. | Proteo genomics | 
| D. | Functional genomics | 
| Answer» E. | |
| 16. | Which of the following theory is supported by the genomic sequence of the obligate intracellular parasite Rickettsia prowazekii ? | 
| A. | Parasitic bacteria have very large genomes | 
| B. | Parasites have a definite genomic sequence similar to viruses | 
| C. | Mitochondria have evolved from endosymbiotic bacteria | 
| D. | All bacteria evolved from viruses | 
| Answer» D. All bacteria evolved from viruses | |
| 17. | The flow of genetic material in microbial cells usually takes place from | 
| A. | RNA through DNA to proteins | 
| B. | proteins through RNA to DNA | 
| C. | DNA through RNA to proteins | 
| D. | none of these | 
| Answer» D. none of these | |
| 18. | Which of the following is used for determining the location of specific genes within the genome? | 
| A. | Genomics | 
| B. | Annotation | 
| C. | Cloning | 
| D. | Proteomics | 
| Answer» C. Cloning | |
| 19. | Proteomics is | 
| A. | the study of algal genomes | 
| B. | a branch of quantum physics dealing with proteins | 
| C. | the study of formation of lipo-protein in animals | 
| D. | the study of the entire collection of proteins expressed by an organism | 
| Answer» E. | |
| 20. | Which of the following is concerned with the management and analysis of biological data using computers? | 
| A. | Bio-physics | 
| B. | Bioinformatics | 
| C. | Genomics | 
| D. | Biomechanics | 
| Answer» C. Genomics | |
| 21. | Why Deinococcus radiodurans is able to survive massive exposure to radiation? | 
| A. | Because it produces a thick shell which acts as a shield from the radiation | 
| B. | Because it has unique DNA repair mechanisms | 
| C. | Because its cellwall contains radioactive elements | 
| D. | Because it has many copies of genes encoding DNA repair | 
| Answer» E. | |
| 22. | Which of the following is the study of the molecular organization of genomes, their information content and the gene products they encode? | 
| A. | Genetics | 
| B. | Ergonomics | 
| C. | Genomics | 
| D. | Bioinformatics | 
| Answer» D. Bioinformatics | |
| 23. | The word, used for the small solid supports onto which are spotted hundreds of thousands of tiny drops of DNA that can be used to screen gene expression, is | 
| A. | southern blot | 
| B. | cloning library | 
| C. | DNA microarrays | 
| D. | northern blot | 
| Answer» D. northern blot | |
| 24. | Which of the following organisms has the smallest genome? | 
| A. | <i>H. influenzae</i> | 
| B. | <i>M. genitalium</i> | 
| C. | <i>M. tuberculosis</i> | 
| D. | None of these | 
| Answer» C. <i>M. tuberculosis</i> | |
| 25. | Studies of similarities and differences among the genomes of multiple organisms is carried out in | 
| A. | comparative genomics | 
| B. | proteomics | 
| C. | functional genomics | 
| D. | structural genomics | 
| Answer» B. proteomics | |
| 26. | The physical nature of genomes is studied under | 
| A. | structural genomics | 
| B. | comparative genomics | 
| C. | proteo genomics | 
| D. | functional genomics | 
| Answer» B. comparative genomics | |
| 27. | Why the bacterium Treponema pallidum is difficult to culture? | 
| A. | Because it requires a great deal of water to reproduce | 
| B. | Because it is unable to use carbohydrates as an energy source | 
| C. | Because it lacks the genes needed for TCA cycle and oxidative phosphorylation | 
| D. | Because it requires extremely low temperature at which water freezes | 
| Answer» D. Because it requires extremely low temperature at which water freezes | |
| 28. | The species of bacteria, which possesses 250 genes for lipid biosynthesis is | 
| A. | <i>M. genitalium</i> | 
| B. | <i>M. tuberculosis</i> | 
| C. | <i>E. coli</i> | 
| D. | <i>H. influenzae</i> | 
| Answer» C. <i>E. coli</i> | |
| 29. | Which type of genomics studies the transcripts and proteins expressed by a genome? | 
| A. | Comparative genomics | 
| B. | Structural genomics | 
| C. | Proteo genomics | 
| D. | Functional genomics | 
| Answer» E. | |
| 30. | What is the range of minimum set of genes required for life? | 
| A. | 50-100 genes | 
| B. | 250-350 genes | 
| C. | 1000-1500 genes | 
| D. | 1500-2000 genes | 
| Answer» C. 1000-1500 genes | |