MCQOPTIONS
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This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
After the binding of polymerase to the DNA template the σ factor is ejected. |
| A. | True |
| B. | False |
| Answer» C. | |
| 2. |
The ternary complex is formed by the polymerase, DNA duplex and the nascent RNA. |
| A. | True |
| B. | False |
| Answer» C. | |
| 3. |
RNA polymerase adds the nucleotides de novo. The first nucleotide added by the polymerase is ____________ |
| A. | ATP |
| B. | TTP |
| C. | GTP |
| D. | CTP |
| Answer» B. TTP | |
| 4. |
Region 1.1 of the σ factor mimics the DNA and is negatively charged. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 5. |
The channel that allows the exit of the coding strand is known as ____________ |
| A. | NTP channel |
| B. | NT channel |
| C. | T channel |
| D. | Downstream DNA channel |
| Answer» C. T channel | |
| 6. |
How many channels are found in the RNA polymerase clamp? |
| A. | 3 |
| B. | 4 |
| C. | 5 |
| D. | 6 |
| Answer» D. 6 | |
| 7. |
With respect to the formation of a complex between polymerase and DNA template which of the following is correct? |
| A. | Open: reversible; Closed: irreversible |
| B. | Open: irreversible; Closed: reversible |
| C. | Open and closed: reversible |
| D. | Open and closed: irreversible |
| Answer» C. Open and closed: reversible | |
| 8. |
The isomerisation of σ70 of bacterial polymerase is an energy dependent process. |
| A. | True |
| B. | False |
| Answer» C. | |
| 9. |
To facilitate binding of σ70 the melting of the template and non – template strands occurs between the positions ____________ |
| A. | -11 to +3 |
| B. | -9 to +5 |
| C. | -10 to +1 |
| D. | -10 to +2 |
| Answer» B. -9 to +5 | |
| 10. |
Without using primers for RNA synthesis the polymerase produces small stretches of RNA of _____________ nucleotides. |
| A. | 8 |
| B. | 10 |
| C. | 12 |
| D. | 14 |
| Answer» C. 12 | |