MCQOPTIONS
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MCQOPTIONS
This section includes 24 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
T cell receptors (or TCR) on CD4+ T cells |
| A. | recognize peptides not associated with MHC molecules |
| B. | recognize peptides associated with MHC class I molecules |
| C. | recognize peptides associated with MHC class II molecules |
| D. | are secreted out into the environment to bind antigens |
| Answer» D. are secreted out into the environment to bind antigens | |
| 2. |
Large parasites such as helminthes may be killed extracellularly by the action of |
| A. | basophils |
| B. | monocytes |
| C. | eosinophils |
| D. | neutrophils |
| Answer» D. neutrophils | |
| 3. |
Lysozyme is present in |
| A. | sweat |
| B. | Cerebro spinal fluid (CSF) |
| C. | urine |
| D. | saliva |
| Answer» E. | |
| 4. |
Which of the following proteins would not need localization signal? |
| A. | A nuclear protein |
| B. | A cytosolic protein |
| C. | A protein bound to the endoplasmic reticulum (ER) membrane |
| D. | A cell surface protein |
| Answer» C. A protein bound to the endoplasmic reticulum (ER) membrane | |
| 5. |
The role of the M cell is to |
| A. | trap virus in mucus and prevent entry |
| B. | induce apoptosis in virus-infected small intestinal epithelia cells |
| C. | pass bacteria or virus to underlying macrophages for processing and presentation of antigen |
| D. | they use their cilia to propel mucus out of the small intestine |
| Answer» D. they use their cilia to propel mucus out of the small intestine | |
| 6. |
Which of the following statements is false regarding B cells? |
| A. | B cells can undergo class switching and produce a different antibody type |
| B. | B one marrow stem cells migrate to the thymus and develop into B cells |
| C. | B cells synthesize antibodies and put them on their cell surface |
| D. | B cells that recognize high concentrations of antigens (self) in the absence of other signals undergo apoptosis in the bone marrow |
| Answer» C. B cells synthesize antibodies and put them on their cell surface | |
| 7. |
Following are the defenses of the colon except |
| A. | sIgA |
| B. | fast flow rate |
| C. | dense resident microbiota |
| D. | mucus |
| Answer» C. dense resident microbiota | |
| 8. |
Natural killer cells are involved in |
| A. | tumour rejection |
| B. | allograft rejection |
| C. | non-specific killing of virus transformed target cells |
| D. | all of these |
| Answer» E. | |
| 9. |
Which of the following(s) is/are the determinants of antigenicity? |
| A. | Chemical nature |
| B. | Size of the antigen |
| C. | Foreignness |
| D. | All of these |
| Answer» E. | |
| 10. |
Immunity is not long lasting to |
| A. | influenza |
| B. | whooping cough |
| C. | diphtheria |
| D. | mumps |
| Answer» B. whooping cough | |
| 11. |
Cytotoxic T-cells can be recognized by which of the following cell surface marker? |
| A. | CD4 |
| B. | CD7 |
| C. | CD8 |
| D. | CD9 |
| Answer» D. CD9 | |
| 12. |
Which is not an antigen-presenting cell (or APC)? |
| A. | B cell |
| B. | Polymorphonuclear leukocyte (or PMN) |
| C. | Dendritic cell |
| D. | All of the above |
| Answer» C. Dendritic cell | |
| 13. |
Chemically an antigen may be |
| A. | lipid |
| B. | protein |
| C. | polysaccharide |
| D. | any of these |
| Answer» E. | |
| 14. |
Which of the following expresses CD3 surface antigen? |
| A. | Granulocytes |
| B. | T cells |
| C. | Monocytes |
| D. | B cells |
| Answer» C. Monocytes | |
| 15. |
Polymorphonuclear leukocytes (or PMNs) |
| A. | can be attracted to the site of an infection following activation of complement |
| B. | are derived from bone marrow stem cells |
| C. | are a type of phagocyte that can engulf and kill bacteria |
| D. | all of the above |
| Answer» E. | |
| 16. |
Major Histo Compatibility Complex (MHC) is a collection of genes arrayed on |
| A. | chromosome 21 in man, chromosome 6 in mice |
| B. | chromosome 6 in man, chromosone 21 in mice |
| C. | chromosome 17in man, chromosome 6 in mice |
| D. | chromosome 6 in man, chromosome 17 in mice |
| Answer» E. | |
| 17. |
CD8 surface antigen is present in |
| A. | cytotoxic T cells |
| B. | suppresssor T cells |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 18. |
Treatment with bacterial endotoxins results blast formation in |
| A. | B cells |
| B. | T cells |
| C. | monocytes |
| D. | none of these |
| Answer» B. T cells | |
| 19. |
Passive immunization is done for |
| A. | tuberculosis |
| B. | diphtheria |
| C. | enteric fever |
| D. | all of these |
| Answer» C. enteric fever | |
| 20. |
Which of the following is correct for isoantigens? |
| A. | They are antigens found in all members of different species |
| B. | They are antigens found in some members of a species |
| C. | They are antigens found in all members of a species |
| D. | They are antigens found in some members of different species |
| Answer» C. They are antigens found in all members of a species | |
| 21. |
Numerous antibodies can be prepared, against one antigen, each binds to unique epitopes. How is this antibody diversity generated? |
| A. | By rearrangements of the DNA encoding the variable regions of the heavy and light chains |
| B. | By the combination of different heavy and light chains that form the antigen binding site |
| C. | Antibody proteins can physically change their shape to bind different epitopes |
| D. | Both (a) and (b) |
| Answer» E. | |
| 22. |
Which of the following is correct for CD8 T cells? |
| A. | CD8 T cells only recognize virus-infected cells |
| B. | CD8 T cell receptor recognizes epitopes that are also commonly recognized by B cells |
| C. | In the thymus, CD8 T cells undergo positive selection only, whereas CD4 T cells undergo negative selection only |
| D. | CD8 T cells can kill individual virus-infected cells in a contact dependent fashion |
| Answer» E. | |
| 23. |
Macrophages are professional antigen- presenting cells. The protein molecule through which they present antigen in human is |
| A. | actin |
| B. | interleukin |
| C. | HLA |
| D. | CD8 |
| Answer» E. | |
| 24. |
T cell receptors (or TCR) on CD4+ T cells |
| A. | recognize peptides not associated with MHC molecules |
| B. | recognize peptides associated with MHC class I molecules |
| C. | recognize peptides associated with MHC class II molecules |
| D. | are secreted out into the environment to bind antigens |
| Answer» D. are secreted out into the environment to bind antigens | |