Explore topic-wise MCQs in Molecular Biology.

This section includes 10 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.

1.

Association of DNA and histone is mediated by _________

A. Covalent bonding
B. Hydrogen bonding
C. Hydrophobic bonding
D. Vander Waals interactions
Answer» C. Hydrophobic bonding
Discussion
2.

How many contacts are observed between the DNA and the histone core protein?

A. 14
B. 21
C. 54
D. 17
Answer» B. 21
Discussion
3.

With respect to the “tails” of the histone molecules which of the following is not true?

A. N – terminal extension
B. Lacks defined structure
C. Required for the association of nucleosome
D. Sites for extensive modifications
Answer» D. Sites for extensive modifications
Discussion
4.

Which of the following histone pairs forms tetramers in solution?

A. H1, H2A
B. H2A, H2B
C. H2B, H3
D. H3, H4
Answer» E.
Discussion
5.

With respect to assembly of every core histone which of the following is wrong?

A. A conserved region
B. Histone fold domain
C. Disc shaped structure
D. 2 α helices and an unstructured loop
Answer» E.
Discussion
6.

Histones have a high content of negatively charged amino acids.

A. True
B. False
Answer» C.
Discussion
7.

Nucleosome is made up of __________

A. DNA, histone core protein
B. DNA, histone core protein, linker H1
C. RNA, histone core protein
D. RNA, histone core protein, linker H1
Answer» C. RNA, histone core protein
Discussion
8.

How many types of histone molecules are found in nature?

A. 3
B. 4
C. 5
D. 6
Answer» D. 6
Discussion
9.

The unpacked stretches of DNA are the extra chromosomal load found in the eukaryotic genome.

A. True
B. False
Answer» C.
Discussion
10.

In the beads on a string model, the bead is made up of __________

A. 6 histone proteins
B. 8 histone proteins
C. 6 histone proteins and DNA
D. 8 histone proteins and DNA
Answer» C. 6 histone proteins and DNA
Discussion