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This section includes 27 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
1. |
Name the coated vesicle which is used to transfer protein from plasma membrane to endosome? |
A. | Clathrin |
B. | COP I |
C. | COP II |
D. | COP III |
Answer» B. COP I | |
2. |
Which of the following coated vesicle transport protein from ER to Golgi? |
A. | Clathrin |
B. | COP II |
C. | COP I |
D. | COP III |
Answer» C. COP I | |
3. |
Glycolipids are synthesized in the ER and ____________ |
A. | Nucleus |
B. | Golgi complex |
C. | Mitochondrion |
D. | Plasma membrane |
Answer» C. Mitochondrion | |
4. |
Hydrophobic transmembrane segments of which proteins are not synthesized in the endoplasmic reticulum? |
A. | integral membrane proteins |
B. | lysosomal proteins |
C. | steroids |
D. | secretory proteins |
Answer» B. lysosomal proteins | |
5. |
The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment. |
A. | hydrolyzed bonds |
B. | hydrophobic bonds |
C. | disulfide bonds |
D. | hydrophilic bonds |
Answer» D. hydrophilic bonds | |
6. |
Which of the following enzyme present in the rough endoplasmic reticulum removes the signal sequence from nascent polypeptides? |
A. | signal oxidase |
B. | signal peptidase |
C. | olisaccharyltransferase |
D. | luciferase |
Answer» C. olisaccharyltransferase | |
7. |
Translocon is a ____________ |
A. | polypeptide |
B. | protein channel |
C. | receptor |
D. | recognition particle |
Answer» C. receptor | |
8. |
In mammalian cells, the signal recognition particle (SRP) consists of ____ distinct polypeptides and one small RNA molecule. |
A. | 2 |
B. | 4 |
C. | 6 |
D. | 8 |
Answer» D. 8 | |
9. |
In yeast cells, protein transport across the endoplasmic reticulum membrane occurs __________ |
A. | perpendicularly |
B. | discontinuously |
C. | co-translationally |
D. | post-translationally |
Answer» E. | |
10. |
In the image below, endoplasmic reticulum is depicted by ________ |
A. | a |
B. | b |
C. | c |
D. | d |
Answer» B. b | |
11. |
The signal sequence that determines whether a protein will be synthesized on a free ribosome or ribosome attached to endoplasmic reticulum is located at _______ |
A. | N-terminal |
B. | C-terminal |
C. | hydrophobic tail |
D. | hydrophilic tail |
Answer» B. C-terminal | |
12. |
Sarcoplasmic reticulum is found in ________________ |
A. | liver cells |
B. | kidney cells |
C. | muscle cells |
D. | neurons |
Answer» D. neurons | |
13. |
Which enzymes are responsible for detoxification of organic compounds carried out by the smooth endoplasmic reticulum? |
A. | Dehydrogenases |
B. | Oxygenases |
C. | Nucleases |
D. | Ribonucleases |
Answer» C. Nucleases | |
14. |
Detoxification of organic compounds like barbiturates and ethanol in the liver is carried out by ________________ |
A. | smooth endoplasmic reticulum |
B. | sarcoplasmic reticulum |
C. | rough endoplasmic reticulum |
D. | nucleus |
Answer» B. sarcoplasmic reticulum | |
15. |
All the cells contain the same ratio of rough and smooth endoplasmic reticulum. |
A. | True |
B. | False |
Answer» C. | |
16. |
Which of the following biomolecules are not synthesized by the endoplasmic reticulum? |
A. | Proteins |
B. | Lipids |
C. | Nucleic acids |
D. | Cholesterol |
Answer» D. Cholesterol | |
17. |
The membranes of rough endoplasmic reticulum (RER) and smooth endoplasmic reticulum (SER) are continuous. |
A. | True |
B. | False |
Answer» B. False | |
18. |
WHICH_OF_THE_FOLLOWING_COATED_VESICLE_TRANSPORT_PROTEIN_FROM_ER_TO_GOLGI??$ |
A. | Clathrin |
B. | COP II |
C. | COP I |
D. | COP III |
Answer» C. COP I | |
19. |
Name_the_coated_vesicle_which_is_used_to_transfer_protein_from_plasma_membrane_to_endosome?$ |
A. | Clathrin |
B. | COP I |
C. | COP II |
D. | COP III |
Answer» B. COP I | |
20. |
Name the sequence which allows the resident protein to retain in ER lumen? |
A. | KDEL |
B. | KKXX |
C. | KLDE |
D. | KXXK |
Answer» B. KKXX | |
21. |
Name the site where detoxification of xenobiotic compounds takes place? |
A. | Cytosol |
B. | RER |
C. | SER |
D. | Ribosome |
Answer» D. Ribosome | |
22. |
Which of the following is not the function of Glycosylation? |
A. | Helps in proper folding of the protein |
B. | Confer stability in proteins |
C. | Helps in cell-cell adhesion |
D. | Synthesis of membrane lipid |
Answer» E. | |
23. |
Name the antibiotic which inhibits the synthesis of oligosaccharides? |
A. | Tunicamycin |
B. | Cephalosporins |
C. | Penicillins |
D. | Ofloxacin |
Answer» B. Cephalosporins | |
24. |
Endoplasmic reticulum membrane which is associated with ribosomes is called_______ |
A. | ER lumen |
B. | Smooth endoplasmic reticulum |
C. | Rough endoplasmic reticulum |
D. | Endosome |
Answer» D. Endosome | |
25. |
What is microsome? |
A. | Compartment of Golgi |
B. | Smaller ribosomes |
C. | Small ER compartments |
D. | Small vesicles of fragmented ER |
Answer» E. | |
26. |
Protein undergoes modifications in ER before reaching their final destination. |
A. | True |
B. | False |
Answer» B. False | |
27. |
Which of the following is the largest single membrane-bound intracellular compartment? |
A. | Ribosome |
B. | Golgi apparatus |
C. | Nucleus |
D. | Endoplasmic reticulum |
Answer» E. | |