 
			 
			MCQOPTIONS
 Saved Bookmarks
				This section includes 27 Mcqs, each offering curated multiple-choice questions to sharpen your Life Sciences knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Name the coated vesicle which is used to transfer protein from plasma membrane to endosome? | 
| A. | Clathrin | 
| B. | COP I | 
| C. | COP II | 
| D. | COP III | 
| Answer» B. COP I | |
| 2. | Which of the following coated vesicle transport protein from ER to Golgi? | 
| A. | Clathrin | 
| B. | COP II | 
| C. | COP I | 
| D. | COP III | 
| Answer» C. COP I | |
| 3. | Glycolipids are synthesized in the ER and ____________ | 
| A. | Nucleus | 
| B. | Golgi complex | 
| C. | Mitochondrion | 
| D. | Plasma membrane | 
| Answer» C. Mitochondrion | |
| 4. | Hydrophobic transmembrane segments of which proteins are not synthesized in the endoplasmic reticulum? | 
| A. | integral membrane proteins | 
| B. | lysosomal proteins | 
| C. | steroids | 
| D. | secretory proteins | 
| Answer» B. lysosomal proteins | |
| 5. | The cysteine residues present in the reduced form in peptides that enter the endoplasmic reticulum lumen are converted into ____________ when they leave the compartment. | 
| A. | hydrolyzed bonds | 
| B. | hydrophobic bonds | 
| C. | disulfide bonds | 
| D. | hydrophilic bonds | 
| Answer» D. hydrophilic bonds | |
| 6. | Which of the following enzyme present in the rough endoplasmic reticulum removes the signal sequence from nascent polypeptides? | 
| A. | signal oxidase | 
| B. | signal peptidase | 
| C. | olisaccharyltransferase | 
| D. | luciferase | 
| Answer» C. olisaccharyltransferase | |
| 7. | Translocon is a ____________ | 
| A. | polypeptide | 
| B. | protein channel | 
| C. | receptor | 
| D. | recognition particle | 
| Answer» C. receptor | |
| 8. | In mammalian cells, the signal recognition particle (SRP) consists of ____ distinct polypeptides and one small RNA molecule. | 
| A. | 2 | 
| B. | 4 | 
| C. | 6 | 
| D. | 8 | 
| Answer» D. 8 | |
| 9. | In yeast cells, protein transport across the endoplasmic reticulum membrane occurs __________ | 
| A. | perpendicularly | 
| B. | discontinuously | 
| C. | co-translationally | 
| D. | post-translationally | 
| Answer» E. | |
| 10. | In the image below, endoplasmic reticulum is depicted by ________ | 
| A. | a | 
| B. | b | 
| C. | c | 
| D. | d | 
| Answer» B. b | |
| 11. | The signal sequence that determines whether a protein will be synthesized on a free ribosome or ribosome attached to endoplasmic reticulum is located at _______ | 
| A. | N-terminal | 
| B. | C-terminal | 
| C. | hydrophobic tail | 
| D. | hydrophilic tail | 
| Answer» B. C-terminal | |
| 12. | Sarcoplasmic reticulum is found in ________________ | 
| A. | liver cells | 
| B. | kidney cells | 
| C. | muscle cells | 
| D. | neurons | 
| Answer» D. neurons | |
| 13. | Which enzymes are responsible for detoxification of organic compounds carried out by the smooth endoplasmic reticulum? | 
| A. | Dehydrogenases | 
| B. | Oxygenases | 
| C. | Nucleases | 
| D. | Ribonucleases | 
| Answer» C. Nucleases | |
| 14. | Detoxification of organic compounds like barbiturates and ethanol in the liver is carried out by ________________ | 
| A. | smooth endoplasmic reticulum | 
| B. | sarcoplasmic reticulum | 
| C. | rough endoplasmic reticulum | 
| D. | nucleus | 
| Answer» B. sarcoplasmic reticulum | |
| 15. | All the cells contain the same ratio of rough and smooth endoplasmic reticulum. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 16. | Which of the following biomolecules are not synthesized by the endoplasmic reticulum? | 
| A. | Proteins | 
| B. | Lipids | 
| C. | Nucleic acids | 
| D. | Cholesterol | 
| Answer» D. Cholesterol | |
| 17. | The membranes of rough endoplasmic reticulum (RER) and smooth endoplasmic reticulum (SER) are continuous. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 18. | WHICH_OF_THE_FOLLOWING_COATED_VESICLE_TRANSPORT_PROTEIN_FROM_ER_TO_GOLGI??$ | 
| A. | Clathrin | 
| B. | COP II | 
| C. | COP I | 
| D. | COP III | 
| Answer» C. COP I | |
| 19. | Name_the_coated_vesicle_which_is_used_to_transfer_protein_from_plasma_membrane_to_endosome?$ | 
| A. | Clathrin | 
| B. | COP I | 
| C. | COP II | 
| D. | COP III | 
| Answer» B. COP I | |
| 20. | Name the sequence which allows the resident protein to retain in ER lumen? | 
| A. | KDEL | 
| B. | KKXX | 
| C. | KLDE | 
| D. | KXXK | 
| Answer» B. KKXX | |
| 21. | Name the site where detoxification of xenobiotic compounds takes place? | 
| A. | Cytosol | 
| B. | RER | 
| C. | SER | 
| D. | Ribosome | 
| Answer» D. Ribosome | |
| 22. | Which of the following is not the function of Glycosylation? | 
| A. | Helps in proper folding of the protein | 
| B. | Confer stability in proteins | 
| C. | Helps in cell-cell adhesion | 
| D. | Synthesis of membrane lipid | 
| Answer» E. | |
| 23. | Name the antibiotic which inhibits the synthesis of oligosaccharides? | 
| A. | Tunicamycin | 
| B. | Cephalosporins | 
| C. | Penicillins | 
| D. | Ofloxacin | 
| Answer» B. Cephalosporins | |
| 24. | Endoplasmic reticulum membrane which is associated with ribosomes is called_______ | 
| A. | ER lumen | 
| B. | Smooth endoplasmic reticulum | 
| C. | Rough endoplasmic reticulum | 
| D. | Endosome | 
| Answer» D. Endosome | |
| 25. | What is microsome? | 
| A. | Compartment of Golgi | 
| B. | Smaller ribosomes | 
| C. | Small ER compartments | 
| D. | Small vesicles of fragmented ER | 
| Answer» E. | |
| 26. | Protein undergoes modifications in ER before reaching their final destination. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 27. | Which of the following is the largest single membrane-bound intracellular compartment? | 
| A. | Ribosome | 
| B. | Golgi apparatus | 
| C. | Nucleus | 
| D. | Endoplasmic reticulum | 
| Answer» E. | |