 
			 
			MCQOPTIONS
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				This section includes 14 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Nonsense mutation is also known as ___________ | 
| A. | Missense mutation | 
| B. | Frame shift mutation | 
| C. | Stop mutation | 
| D. | Reverse mutation | 
| Answer» D. Reverse mutation | |
| 2. | Which of the following disease is caused by missense mutation? | 
| A. | Thalassemia | 
| B. | Sickle cell anemia | 
| C. | Hemophilia | 
| D. | Cystic fibriosis | 
| Answer» C. Hemophilia | |
| 3. | The alterations that change a codon specific for one amino acid to a codon specific for another amino acid is known as ___________ | 
| A. | Missense mutation | 
| B. | Nonsense mutation | 
| C. | Frame shift mutation | 
| D. | Reverse Mutation | 
| Answer» B. Nonsense mutation | |
| 4. | How many types of point mutations are able to alter the Genetic code? | 
| A. | 1 | 
| B. | 2 | 
| C. | 3 | 
| D. | 4 | 
| Answer» D. 4 | |
| 5. | IREs for the process of translation is present in viruses. Their function resembles that of eukaryotic ribosome. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 6. | The initiation factors are closely associated with the 3 end of mRNA through the initiation between the eIF4F and the ___________ | 
| A. | Poly A tail | 
| B. | Poly A binding proteins | 
| C. | Small subunit of ribosome | 
| D. | Large subunit of ribosome | 
| Answer» C. Small subunit of ribosome | |
| 7. | mRNA scanning is a cost-effective mechanism. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 8. | Which of the following protein interacts with the eIF4F for recruiting the pre-initiation complex to the mRNA? | 
| A. | eIF1 | 
| B. | eIF2 | 
| C. | eIF3 | 
| D. | eIF4 | 
| Answer» D. eIF4 | |
| 9. | Recognition of mRNA by 43S pre-initiation complex is mediated by the enzyme ___________ | 
| A. | eIF2-GTP | 
| B. | eIF4F | 
| C. | eIF5B-GTP | 
| D. | eIF1 | 
| Answer» C. eIF5B-GTP | |
| 10. | Which of the following eukaryotic proteins is an analog of IF2-GTP? | 
| A. | eIF2B-GTP | 
| B. | eIF2-GTP | 
| C. | eIF5B-GTP | 
| D. | eIF4G | 
| Answer» D. eIF4G | |
| 11. | The first amino acid to be incorporated in the eukaryotic polypeptide is ___________ | 
| A. | Methionine | 
| B. | Valine | 
| C. | N-formyl methionine | 
| D. | N-acyl valine | 
| Answer» B. Valine | |
| 12. | The same number of auxiliary proteins is used to drive the initiation process of both prokaryotes and eukaryotes. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 13. | Eukaryotic mRNA generally codes for a single protein because the eukaryotic translation includes ____________ | 
| A. | A single ORF | 
| B. | Monocistronic codons | 
| C. | Polycistronic codons | 
| D. | Starts at the first triplet codon | 
| Answer» C. Polycistronic codons | |
| 14. | The subunit association with the mRNA occurs before tRNA recruitment in the case of both eukaryotes and prokaryotes. | 
| A. | True | 
| B. | False | 
| Answer» C. | |