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This section includes 334 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Viruses are larger than prions. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 2. |
Satellite viruses do not encode enzymes for replication. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 3. |
Measles virus belong to the family ______________ |
| A. | Paramoxyviridae |
| B. | Filoviridae |
| C. | Bunyaviridae |
| D. | Flaviviridae |
| Answer» B. Filoviridae | |
| 4. |
In which year was ICTV established? |
| A. | 1960 |
| B. | 1965 |
| C. | 1963 |
| D. | 1966 |
| Answer» E. | |
| 5. |
Which of the following class consists of ambisense viruses? |
| A. | Class 5 |
| B. | Class 7 |
| C. | Class 2 |
| D. | Class 4 |
| Answer» B. Class 7 | |
| 6. |
Class III of Baltimore classification contains viruses with __________ |
| A. | dsDNA |
| B. | dsRNA |
| C. | ssRNA |
| D. | ssDNA |
| Answer» C. ssRNA | |
| 7. |
Which of the following class contains all viruses that have dsDNA genomes? |
| A. | Class I |
| B. | Class II |
| C. | Class III |
| D. | Class IV |
| Answer» B. Class II | |
| 8. |
The Baltimore classification was based on the importance of ____________ |
| A. | DNA |
| B. | mRNA |
| C. | rRNA |
| D. | tRNA |
| Answer» C. rRNA | |
| 9. |
Which of the following viruses are icosahedrons? |
| A. | Filamentous virus |
| B. | Complex virus |
| C. | Simple virus |
| D. | Isometric virus |
| Answer» E. | |
| 10. |
Which of the following virus causes shingles when it is reactivated? |
| A. | Varicella zoster |
| B. | Adenovirus |
| C. | HPV |
| D. | Aichi virus |
| Answer» B. Adenovirus | |
| 11. |
Which of the following has responsibility for the assignment of new viruses to specific groupings? |
| A. | ICC |
| B. | ICTV |
| C. | ITC |
| D. | RCM |
| Answer» C. ITC | |
| 12. |
Poliovirus damages which of following cells? |
| A. | bone cells |
| B. | vessels |
| C. | muscle cells |
| D. | mature nerve cells |
| Answer» E. | |
| 13. |
Ebola causes which of following diseases? |
| A. | chicken pox |
| B. | common cold |
| C. | diarrhea |
| D. | hemorrhage |
| Answer» E. | |
| 14. |
The viral nucleocapsid is the combination of |
| A. | genome and capsid |
| B. | capsid and spikes |
| C. | envelope and capsid |
| D. | capsomere and genome |
| Answer» B. capsid and spikes | |
| 15. |
Which of the following is the agent associated with the development of neurodegenerative disease in livestock and humans? |
| A. | Prions |
| B. | Viroids |
| C. | virions |
| D. | Virinos |
| Answer» B. Viroids | |
| 16. |
A change from lysogeny to lysis is generally induced by |
| A. | ultraviolet light |
| B. | chemicals |
| C. | irradiation |
| D. | all of these |
| Answer» B. chemicals | |
| 17. |
Which of following drug inhibits HIV replication by interfering with synthesis of viral DNA? |
| A. | ribavirin |
| B. | acyclovir |
| C. | Adefovir |
| D. | Azidothymidine |
| Answer» E. | |
| 18. |
Which of following is largest virus? |
| A. | pandora virus |
| B. | Mimi virus |
| C. | PicoRNA virus |
| D. | influenza virus |
| Answer» B. Mimi virus | |
| 19. |
Attachment of receptors and virus, known to be |
| A. | Random |
| B. | Specific |
| C. | Irregular |
| D. | Regular |
| Answer» C. Irregular | |
| 20. |
Viral RNA is replicated in the host cell |
| A. | cytoplasmic matrix |
| B. | nucleus |
| C. | mitochondria |
| D. | lysozomes |
| Answer» B. nucleus | |
| 21. |
Which of following has 8 different RNA molecules? |
| A. | t4 |
| B. | tobacco mosaic virus |
| C. | adenovirus |
| D. | influenza virus |
| Answer» E. | |
| 22. |
Viruses can be purified based on their size and density by using |
| A. | gradient centrifugation |
| B. | differential centrifugation |
| C. | precipitation |
| D. | none of these |
| Answer» B. differential centrifugation | |
| 23. |
Viruses that contain host cell 'DNA' instead of viral 'DNA' is known as |
| A. | Virion |
| B. | Prion |
| C. | Bacteriophages |
| D. | Pseudoviruses |
| Answer» E. | |
| 24. |
'Viroid' cause diseases rarely in humans, but , mostly in |
| A. | Plants |
| B. | Animals |
| C. | Horses |
| D. | Camels |
| Answer» B. Animals | |
| 25. |
Which of the following is an example of rod-shaped viruses having their capsomeres arranged helically and not in the stacked ring? |
| A. | Bateriophage M13 |
| B. | Bateriophage MV-L2 |
| C. | Bateriophage T2 |
| D. | Bateriophage T4 |
| Answer» B. Bateriophage MV-L2 | |
| 26. |
Which of the following are obligate intracellular parasites? |
| A. | Chlamydia |
| B. | Viruses |
| C. | Rickettsia |
| D. | All of these |
| Answer» E. | |
| 27. |
The symmetry of nucleocapsid of poxvirusps is/are |
| A. | complex |
| B. | icosahedral |
| C. | helical |
| D. | all of these |
| Answer» B. icosahedral | |
| 28. |
Most reliable test for detection of hepatitis E infection is |
| A. | ELISA test for IgM anti-HEV |
| B. | Western blot assay for IgM anti-HEV |
| C. | Polymerase chain reaction for detection of HEV RNA |
| D. | ELISA test for IgG anti-HEV |
| Answer» D. ELISA test for IgG anti-HEV | |
| 29. |
Which of the following is not correct for hepatitis A virus? |
| A. | It can be grown in cell cultures of primate and human cells |
| B. | It is one of the most stable viruses infecting humans |
| C. | It may cause hepatocellular carcinoma |
| D. | None of the above |
| Answer» D. None of the above | |
| 30. |
Infective and complete form of virus with core 'RNA' and capsid outside host cell is called |
| A. | Virion |
| B. | Virus |
| C. | Prion |
| D. | Bacteriophages |
| Answer» B. Virus | |
| 31. |
Genome of Mimivirus contains approximately how many genes? |
| A. | 2000 |
| B. | 200 |
| C. | 1000 |
| D. | 100000 |
| Answer» D. 100000 | |
| 32. |
Myxo used in name of Orthomyxoviruses refers to affinity of virus towards |
| A. | Mucins |
| B. | Mucans |
| C. | Mutation |
| D. | Mixed phenotype |
| Answer» B. Mucans | |
| 33. |
How many identical proteins are arranged on surface of adenoviruses? |
| A. | 252 |
| B. | 919 |
| C. | 781 |
| D. | 100 |
| Answer» B. 919 | |
| 34. |
The infected cells continue to reproduce themselves as well as the virus, and the mature virions are extruded from the cell surface continuously over a long period of time. This type of release mechanism is called a |
| A. | productive infection |
| B. | inductive infection |
| C. | resultant infection |
| D. | all of these |
| Answer» B. inductive infection | |
| 35. |
Which of following in animals is infected by Adenoviruses? |
| A. | respiratory tract |
| B. | circulatory system |
| C. | immune system |
| D. | spleen |
| Answer» B. circulatory system | |
| 36. |
Which of following is common to both viruses and bacteria? |
| A. | ribosomes |
| B. | metabolism |
| C. | genome |
| D. | cell membrane |
| Answer» D. cell membrane | |
| 37. |
Which of following viruses is surrounded by membranous coat? |
| A. | adenovirus |
| B. | t4 bacteriophage |
| C. | virus |
| D. | influenza virus |
| Answer» E. | |
| 38. |
Phage that incorporates its genome in host genome is called |
| A. | t4 phages |
| B. | temperate phages |
| C. | lytic phages |
| D. | prophage |
| Answer» E. | |
| 39. |
How big is tobacco mosaic virus? |
| A. | 250nm |
| B. | 20nm |
| C. | 90nm |
| D. | 100nm |
| Answer» B. 20nm | |
| 40. |
Which of the following disinfectant is effective against viruses? |
| A. | Hydrogen peroxide |
| B. | Hypochlorite |
| C. | Formaldehyde |
| D. | All of these |
| Answer» E. | |
| 41. |
Human common cold virus infects which of following cells? |
| A. | lung cells |
| B. | upper respiratory tract cells |
| C. | muscle cells |
| D. | heart cells |
| Answer» C. muscle cells | |
| 42. |
Which of the following viruses can rescue adenovirus in simian cells? |
| A. | Rabies |
| B. | Vaccinia |
| C. | Simian virus 40 |
| D. | Cytomegalovirus |
| Answer» D. Cytomegalovirus | |
| 43. |
'Prions' lacks |
| A. | Proteins |
| B. | Capsids |
| C. | Nucleic acids |
| D. | Envelope |
| Answer» D. Envelope | |
| 44. |
Virulent and nonvirulent viruses may not |
| A. | inhibit host cell DNA synthesis |
| B. | inhibit host cell RNA synthesis |
| C. | stimulate host cell macromolecule synthesis |
| D. | degrade host cell DNA |
| Answer» E. | |
| 45. |
The agent representing an isolate of hepatitis G virus is |
| A. | GBA-A |
| B. | GBV-B |
| C. | GBV-C |
| D. | none of these |
| Answer» D. none of these | |
| 46. |
The temperate phage possesses a gene that codes for a repressor protein which makes the cell resistant to lysis initiated by |
| A. | the prophage |
| B. | lytic infection by other viruses |
| C. | Both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 47. |
HTLV-1 viruses are associated with which of following cancers? |
| A. | cervical cancer |
| B. | Burkitt's lymphoma |
| C. | breast cancer |
| D. | adult leukemia |
| Answer» E. | |
| 48. |
The defective satellite virus is |
| A. | hepatitis B |
| B. | hepatitis C |
| C. | hepatitis D |
| D. | hepatitis A |
| Answer» D. hepatitis A | |
| 49. |
Reverse transcriptase is a useful enzyme to have when |
| A. | an RNA virus converts its RNA to DNA |
| B. | there are no host cells present |
| C. | nutrients are scarce |
| D. | spikes are forming in the new virus |
| Answer» B. there are no host cells present | |
| 50. |
Size of 'papovavirus' is |
| A. | 22 nm |
| B. | 56 nm |
| C. | 55 nm |
| D. | 40nm |
| Answer» D. 40nm | |