 
			 
			MCQOPTIONS
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				This section includes 24 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | In cancer telomerase activity __________ | 
| A. | Increases | 
| B. | Decreases | 
| C. | Remains constant | 
| D. | Plays no role | 
| Answer» B. Decreases | |
| 2. | Which alternate form of histone is seen in centromeric histones of humans? | 
| A. | H2A.z | 
| B. | SMC protein | 
| C. | H1 | 
| D. | CENP-A | 
| Answer» E. | |
| 3. | The centromere is A/T rich region. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 4. | How many satellite sequence elements are present in yeast centromere? | 
| A. | 2 | 
| B. | 3 | 
| C. | 4 | 
| D. | 5 | 
| Answer» C. 4 | |
| 5. | Centromeric DNA was initially defined in ___________ | 
| A. | Bacteria | 
| B. | Fungi | 
| C. | Yeast | 
| D. | Human | 
| Answer» D. Human | |
| 6. | The protein that binds to the spindle fibres are known as centromeric proteins. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 7. | The whole length of DNA is transcriptionally active. | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 8. | The extent of chromosome coiling in non – dividing cells is _________ | 
| A. | Supercoiled | 
| B. | Euchromatin | 
| C. | Condensed | 
| D. | Heterochromatin | 
| Answer» C. Condensed | |
| 9. | CENTROMERIC_DNA_WAS_INITIALLY_DEFINED_IN____________?$ | 
| A. | Bacteria | 
| B. | Fungi | 
| C. | Yeast | 
| D. | Human | 
| Answer» D. Human | |
| 10. | The centromere is A/T rich region ____$ | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 11. | How_many_satellite_sequence_elements_are_present_in_yeast_centromere?$ | 
| A. | 2 | 
| B. | 3 | 
| C. | 4 | 
| D. | 5 | 
| Answer» C. 4 | |
| 12. | In cancer telomerase activity__________ | 
| A. | Increases | 
| B. | Decreases | 
| C. | Remains constant | 
| D. | Plays no role | 
| Answer» B. Decreases | |
| 13. | How does telomerase activity depend on age? | 
| A. | Directly | 
| B. | Inversely | 
| C. | Remains the same | 
| D. | Does not occur | 
| Answer» E. | |
| 14. | Which of the following nucleotides is rich I telomere of an organism? | 
| A. | A, T | 
| B. | T, G | 
| C. | G, C | 
| D. | C, A | 
| Answer» D. C, A | |
| 15. | Telomere is not related to __________ | 
| A. | Maintenance | 
| B. | Chromosome degradation | 
| C. | Division | 
| D. | Replication | 
| Answer» D. Replication | |
| 16. | Which_alternate_form_of_histone_is_seen_in_centromeric_histones_of_humans? | 
| A. | H2A.z | 
| B. | SMC protein | 
| C. | H1 | 
| D. | CENP-A | 
| Answer» E. | |
| 17. | The protein that binds to the spindle fibres are known as centromeric proteins ________? | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 18. | With respect to centromere which of the following is wrong? | 
| A. | Constricted chromosomal region | 
| B. | Holds the sister chromatids together | 
| C. | Attaches to spindle fibres | 
| D. | Facilitates even distribution | 
| Answer» E. | |
| 19. | The part that plays a critical role in even distribution of parental DNA during division is ___________ | 
| A. | Telomere | 
| B. | Centromere | 
| C. | Spindle fibre | 
| D. | Centrioles | 
| Answer» C. Spindle fibre | |
| 20. | At which phase do transcription ceases? | 
| A. | Interphase | 
| B. | Prophase | 
| C. | S phase | 
| D. | G phase | 
| Answer» C. S phase | |
| 21. | Why are chromosomes condensed? | 
| A. | To facilitate accommodation | 
| B. | Always condensed | 
| C. | To facilitate cell division | 
| D. | To facilitate distribution in daughter cells | 
| Answer» E. | |
| 22. | The whole length of DNA is transcriptionally active ___________ | 
| A. | True | 
| B. | False | 
| Answer» C. | |
| 23. | The extent of chromosome coiling in non – dividing cells is _________$ | 
| A. | Supercoiled | 
| B. | Euchromatin | 
| C. | Condensed | 
| D. | Heterochromatin | 
| Answer» C. Condensed | |
| 24. | Nucleosome was first described in 1974 by ___________ | 
| A. | William Asbury | 
| B. | Rosalind Franklin | 
| C. | Roger Kornberg | 
| D. | John Crick | 
| Answer» D. John Crick | |