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This section includes 18 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
1. |
Each cycle of β-oxidation produces |
A. | 1 FADH2, 1 NAD+, and 1 acetyl-CoA |
B. | 1 FADH2, 1 NADH and 1 acetyl-CoA |
C. | 1 FADH2, 1 NADH and 2 CO2 molecules |
D. | 1 FAD, 1 NAD+ and 2 CO2 molecules |
Answer» C. 1 FADH2, 1 NADH and 2 CO2 molecules | |
2. |
Which of the following accepts only one electron? |
A. | Cytochrome b |
B. | Coenzyme Q |
C. | FMN |
D. | FAD |
Answer» B. Coenzyme Q | |
3. |
Which one of the following is the one having highest redox potential? |
A. | Ubiquinone |
B. | O2 |
C. | FMN |
D. | NAD |
Answer» C. FMN | |
4. |
Chemiosmotic hypothesis does not involve ____________ |
A. | Only proton transport is strictly regulated, other positively charged ions can diffuse freely across the mitochondrial membrane |
B. | ATPase activity is reversible |
C. | Proton flow into the mitochondria depends on the presence of ADP and Pi |
D. | Electron transport by the respiratory chain pumps protons out of the mitochondria |
Answer» B. ATPase activity is reversible | |
5. |
If rotenone is added to the mitochondrial electron transport chain then ____________ |
A. | Succinate oxidation remains normal |
B. | P: O ratio of NADH is reduced from 3:1 to 2:1 |
C. | Oxidative phosphorylation is uncoupled at site I |
D. | Rate of NADH oxidation is diminished to two-thirds of its initial value |
Answer» B. P: O ratio of NADH is reduced from 3:1 to 2:1 | |
6. |
If the oxidative phosphorylation was uncoupled in the mitochondria then there is a/an ____________ |
A. | Decreased concentration of ADP in the mitochondria |
B. | Decreased oxidative rate |
C. | Increased inorganic phosphate in the mitochondria |
D. | Decreased production of heat |
Answer» D. Decreased production of heat | |
7. |
If 2, 4-dinitrophenol is added to tightly coupled mitochondria that are actively oxidizing succinate ____________ |
A. | Electron flow will continue but ATP synthesis will not occur |
B. | Electron flow will continue but ATP synthesis will be increased |
C. | Electron flow will cease but ATP synthesis will continue |
D. | Both electron flow and ATP synthesis will be ceased |
Answer» B. Electron flow will continue but ATP synthesis will be increased | |
8. |
Effect of valinomycin on oxidative phosphorylation does not involve _____________ |
A. | pH gradient across the inner mitochondrial membrane decreases |
B. | Rate of flow of electrons increases |
C. | Rate of oxygen consumption increases |
D. | Net yield of ATP decreases |
Answer» B. Rate of flow of electrons increases | |
9. |
OUT_OF_THE_FOLLOWING_THE_ONE_HAVING_HIGHEST_REDOX_POTENTIAL_IS?$ |
A. | Ubiquinone |
B. | O<sub>2</sub> |
C. | FMN |
D. | NAD |
Answer» C. FMN | |
10. |
Which_of_the_following_accepts_only_one_electron?$ |
A. | Cytochrome b |
B. | Coenzyme Q |
C. | FMN |
D. | FAD |
Answer» B. Coenzyme Q | |
11. |
Chemiosmotic hypothesis does not involv? |
A. | Only proton transport is strictly regulated, other positively charged ions can diffuse freely across the mitochondrial membrane |
B. | ATPase activity is reversible |
C. | Proton flow in to the mitochondria depends on the presence of ADP and Pi |
D. | Electron transport by the respiratory chain pumps protons out of the mitochondria |
Answer» B. ATPase activity is reversible | |
12. |
Which of the following takes place in substrate level phosphorylation? |
A. | Oxidation of one molecule of substrate is linked to synthesis of more than one ATP molecule |
B. | High energy intermediate compounds cannot be isolated |
C. | Only mitochondrial reactions participate in ATP formation |
D. | Substrate reacts to form a product containing a high energy bond |
Answer» E. | |
13. |
If rotenone is added to the mitochondrial electron transport chain |
A. | Succinate oxidation remains normal |
B. | P: O ratio of NADH is reduced from 3:1 to 2:1 |
C. | Oxidative phosphorylation is uncoupled at site I |
D. | Rate of NADH oxidation is diminished to two-thirds of its initial value |
Answer» B. P: O ratio of NADH is reduced from 3:1 to 2:1 | |
14. |
If the oxidative phosphorylation was uncoupled in the mitochondria then there is a/an |
A. | Decreased concentration of ADP in the mitochondria |
B. | Decreased oxidative rate |
C. | Increased inorganic phosphate in the mitochondria |
D. | Decreased production of heat |
Answer» D. Decreased production of heat | |
15. |
If 2, 4-dinitrophenol is added to tightly coupled mitochondria that are actively oxidizing succinate |
A. | Electron flow will continue but ATP synthesis will not occur |
B. | Electron flow will continue but ATP synthesis will be increased |
C. | Electron flow will cease but ATP synthesis will continue |
D. | Both electron flow and ATP synthesis will be ceased |
Answer» B. Electron flow will continue but ATP synthesis will be increased | |
16. |
If mitochondria were blocked at the site of NADH oxidation and were treated with succinate as substrate, what would the P : O ratio is? |
A. | Same as that normally produced by succinate |
B. | One more than normally produced by succinate |
C. | One less than normally produced by succinate |
D. | Zero |
Answer» B. One more than normally produced by succinate | |
17. |
Effect of valinomycin on oxidative phosphorylation does not involve |
A. | pH gradient across the inner mitochondrial membrane decreases |
B. | Rate of flow of electrons increases |
C. | Rate of oxygen consumption increases |
D. | Net yield of ATP decreases |
Answer» B. Rate of flow of electrons increases | |
18. |
Which of the following is the prosthetic group of NADH dehydrogenase? |
A. | NADH |
B. | FAD |
C. | NADPH |
D. | FMN |
Answer» E. | |