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This section includes 91 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.
51. |
β-Lymphocytes are often called simply |
A. | B cells |
B. | T cells |
C. | T Lymphocytes |
D. | none of these |
Answer» B. T cells | |
52. |
Which species lack immunoglobulin light chains? |
A. | Camels |
B. | Humans |
C. | cows |
D. | Buffalo |
Answer» B. Humans | |
53. |
Which of the following are responsible for immune specificity? |
A. | Antigens |
B. | Antibodies |
C. | T lymphocytes |
D. | Macrophage |
Answer» C. T lymphocytes | |
54. |
Lack of reaction to our own human leukocyte antigens (HLAs) is known as? |
A. | autoimmunity |
B. | complement system |
C. | clonal selection |
D. | tolerance |
Answer» E. | |
55. |
The humoral immune response relies on the production of soluble proteins called |
A. | antibodies |
B. | macromolecules |
C. | lymphocytes |
D. | none of these |
Answer» B. macromolecules | |
56. |
Which of the following is most likely to produce anaphylaxis in a susceptible individual? |
A. | Pollen |
B. | Mold |
C. | Dust |
D. | Bee sting |
Answer» E. | |
57. |
A cell which defends against body cells in which viruses are reproducing is |
A. | Exotoxin |
B. | Cytotoxic T cell |
C. | Endotoxin |
D. | Suppressor T cell |
Answer» C. Endotoxin | |
58. |
Cleavage of an IgG molecule by a specific protease can produce |
A. | an antigen-binding site and two constant regions |
B. | two heavy chain-light chain dimers |
C. | an inactive mixture of oligopeptides |
D. | two Fab fragments and one Fc fragment |
Answer» E. | |
59. |
Which of those immunoglobulin classes is mainly found in external secretions? |
A. | Ig A |
B. | Ig D |
C. | Ig M |
D. | IgE |
Answer» B. Ig D | |
60. |
Papain digest IgG into |
A. | two Fab fragments and one Fc fragment |
B. | three Fab fragments and two Fc fragments |
C. | two Fab fragments and two Fc fragments |
D. | three Fab fragments and three Fc fragments |
Answer» B. three Fab fragments and two Fc fragments | |
61. |
Antibodies can be used |
A. | for the localization of proteins in the cell |
B. | for protein purification |
C. | to catalyze chemical reactions |
D. | all of the above |
Answer» E. | |
62. |
The protein, produced by B cells that binds to a specific antigen is |
A. | phagocyte |
B. | leukocyte |
C. | vaccine |
D. | antibody |
Answer» E. | |
63. |
Which of the following characteristics are common in lymphocytes, macrophages, and neutrophils? |
A. | They are all part of the nonspecific immune response in vertebrates |
B. | They are all part of the specific immune response in vertebrates |
C. | They are all part of the internal defenses of nonvertebrates |
D. | They are all types of white blood cells |
Answer» E. | |
64. |
Which of these is part of the lymphoid system in humans? |
A. | Liver |
B. | Stomach |
C. | Tonsils |
D. | Kidneys |
Answer» D. Kidneys | |
65. |
Antigenic determinants bind to which portions of an antibody? |
A. | Variable regions |
B. | Constant regions |
C. | Only light chains |
D. | Only heavy chains |
Answer» B. Constant regions | |
66. |
Structures of anti-PCP antibody shows that the tight binding of PCP to the antibody is primarily due to |
A. | hydrophobic forces |
B. | electrostatic forces. |
C. | Van der Waals forces. |
D. | none of these |
Answer» B. electrostatic forces. | |
67. |
What type of B cell is like a tiny factory that produces antibodies identical to the B cell receptor that bind to the original antigen? |
A. | T cells |
B. | Memory cells |
C. | Plasma cells |
D. | Macrophages |
Answer» D. Macrophages | |
68. |
Which of the following white blood cells act as scavengers when they engulf and digest pathogens? |
A. | Macrophages |
B. | T cells |
C. | B cells |
D. | Lymphocytes |
Answer» B. T cells | |
69. |
Which of the following components of the vertebrate immune response occurs first upon invasion by a virus or bacterium? |
A. | Activation of killer T lymphocytes |
B. | Activation of B lymphocytes |
C. | The inflammatory response |
D. | Mobilization of complement proteins |
Answer» D. Mobilization of complement proteins | |
70. |
The human IgG class of antibodies is divided into |
A. | five IgG classes |
B. | two IgG classes |
C. | three IgG classes |
D. | four IgG classes |
Answer» E. | |
71. |
Monoclonal refers to |
A. | a single clone of antibody-producing cells |
B. | all the antibody molecules which are identical |
C. | the binding with same antigenic site with identical binding affinities |
D. | all of the above |
Answer» E. | |
72. |
If Class IIMHC is not expressed in the thymus, the resulting immune deficiencies would include all of the following except reduced |
A. | alternative complement activation. |
B. | CD8 T cell-mediated cytotoxicity |
C. | macrophage activation to vesicular pathogens |
D. | IgG synthesis |
Answer» B. CD8 T cell-mediated cytotoxicity | |
73. |
Fab fragment has |
A. | one antigen binding site |
B. | two antigen binding site |
C. | one antibody binding site |
D. | two antibody binding site |
Answer» B. two antigen binding site | |
74. |
Immunological memory is due to |
A. | short lived macrophage that can recognize specific pathogens |
B. | long lived B cells that secrete a specific antibody |
C. | long lived B cells that secrete a specific antigen |
D. | short lived helper T cells that signal macrophage to divide |
Answer» C. long lived B cells that secrete a specific antigen | |
75. |
IgE provides |
A. | immunity against some parasites |
B. | complement killings of the cells and phagocytosis |
C. | secretions in the body |
D. | all of the above |
Answer» B. complement killings of the cells and phagocytosis | |
76. |
Which of the Rous sarcoma virus has a homologous cellular protein? |
A. | c-src |
B. | v-src |
C. | v-ha-src |
D. | v-ha-ras |
Answer» B. v-src | |
77. |
A monoclonal antibody (mAb) specific for the 2,4-dinitrophenyl (DNP) hapten might also bind |
A. | Leu or Ileu |
B. | His or Pro |
C. | Tyr or Phe |
D. | Ser or Thr |
Answer» D. Ser or Thr | |
78. |
The immunoglobulin fold is |
A. | found only in IgG molecules |
B. | a β-barrel composed of a three- and a four-stranded antiparallel β-sheet |
C. | both (a) and (b) |
D. | found six times in the IgG molecule |
Answer» C. both (a) and (b) | |
79. |
What is a protein produced by host cells infected by viruses? |
A. | Interferon |
B. | Histamine |
C. | Antiserum |
D. | Vaccine |
Answer» B. Histamine | |
80. |
Type A blood |
A. | can be used to donate to type AB individuals |
B. | can be used to donate to type B individuals |
C. | contains type B antigens on the surface of red blood cells |
D. | can always be used to donate to an Rh+ individual |
Answer» B. can be used to donate to type B individuals | |
81. |
Which of the following blood proteins can destroy pathogens? |
A. | Major histocompatibility complex |
B. | Platelets |
C. | Fibrinogen |
D. | Complement system |
Answer» E. | |
82. |
What is the behavior in which T cells and B cells constantly travel throughout the body seeking out and destroying foreign substances? |
A. | Antibody-mediated immune response |
B. | Immune surveillance |
C. | Cell-mediated immune response |
D. | Vaccination |
Answer» C. Cell-mediated immune response | |
83. |
What is the result of invasion of a body by pathogens? |
A. | Infection |
B. | Inflammation |
C. | Swelling |
D. | Pus |
Answer» B. Inflammation | |
84. |
Which of the following produces the antibodies employed in the specific immune response of vertebrates? |
A. | B lymphocytes |
B. | T lymphocytes |
C. | Neutrophils |
D. | Macrophages |
Answer» B. T lymphocytes | |
85. |
In a fetus, where are lymphocytes produced? |
A. | In the spleen |
B. | In the bone marrow |
C. | In the liver |
D. | In the heart |
Answer» D. In the heart | |
86. |
Which of the following is not part of the vertebrate immune system? |
A. | Lymphocytes |
B. | Antibodies |
C. | Cardiac glycosides |
D. | Lymph nodes |
Answer» D. Lymph nodes | |
87. |
In animals, blood clots serve the function of |
A. | consuming invading organisms |
B. | helping them match the background coloration of the habitat |
C. | stimulating production of killer T lymphocytes |
D. | repairing damage to the body wall |
Answer» E. | |
88. |
Which of these is a type of specific defense against pathogens? |
A. | Lymphocytes |
B. | Macrophages |
C. | Phagocytes |
D. | Leukocytes |
Answer» B. Macrophages | |
89. |
The maturation of T cells and the production of particular T cell receptors occurs in the |
A. | thyroid gland |
B. | thymus gland |
C. | testes |
D. | all of these |
Answer» C. testes | |
90. |
What type of B cell remains dormant in the body, but can respond rapidly if the same antigen appears again? |
A. | T cells |
B. | Memory cells |
C. | Plasma cells |
D. | Macrophages |
Answer» C. Plasma cells | |
91. |
Which of the following provide specific defense against viruses and bacteria? |
A. | T cells |
B. | B cells |
C. | Complement |
D. | inflammation |
Answer» C. Complement | |