MCQOPTIONS
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MCQOPTIONS
This section includes 151 Mcqs, each offering curated multiple-choice questions to sharpen your Microbiology knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
In hospitals, surgical instruments and plastics are washed with |
| A. | Ethylene oxide |
| B. | Iodine |
| C. | Tincture |
| D. | Chlorine |
| Answer» B. Iodine | |
| 2. |
Cephalosporins and Penicillins interfere with which of the following? |
| A. | Protein synthesis |
| B. | DNA function |
| C. | Cell membrane function |
| D. | Cell wall synthesis |
| Answer» E. | |
| 3. |
Drugs that inhibit cross linking step in synthesis of murine, inhibits activity of enzyme, known as |
| A. | Trans peptidases |
| B. | Amylase |
| C. | Protease |
| D. | Lipase |
| Answer» B. Amylase | |
| 4. |
Pore size of 'nitrocellulose' is |
| A. | 0.23 µm |
| B. | 0.22 µm |
| C. | 0.21 µm |
| D. | 0.26 µm |
| Answer» C. 0.21 µm | |
| 5. |
With which of the following aminoglycosides interfere? |
| A. | Protein synthesis |
| B. | DNA function |
| C. | Cell wall synthesis |
| D. | Cell membrane function |
| Answer» B. DNA function | |
| 6. |
Staphylococcus epidermidis causes an infection that can be treated with |
| A. | Cephalosporin |
| B. | Vancomycin |
| C. | Bacitracin |
| D. | Cycloserine |
| Answer» C. Bacitracin | |
| 7. |
Meningitis results from meninges become affected through |
| A. | virus only |
| B. | bacteria only |
| C. | fungi |
| D. | virus and bacteria |
| Answer» E. | |
| 8. |
Broad-spectrum antibiotics are developed through |
| A. | erythromycins |
| B. | cephalosporin |
| C. | Tetacyclines |
| D. | Penicillin |
| Answer» D. Penicillin | |
| 9. |
Which of the following tests is used to determine the minimal lethal concentration? |
| A. | Broth dilution test |
| B. | Agar dilution test |
| C. | Dilution susceptibility tests |
| D. | All of these |
| Answer» E. | |
| 10. |
Which of the following is not a semi synthetic chemotherapeutic agent? |
| A. | Ampicillin |
| B. | Carbenicillin |
| C. | Penicillin |
| D. | Sulfonamide |
| Answer» D. Sulfonamide | |
| 11. |
In penicillin production, the pH of culture medium is maintained between |
| A. | 5 and 6 |
| B. | 4 and 6 |
| C. | 6 and 7 |
| D. | 4 and 5 |
| Answer» B. 4 and 6 | |
| 12. |
Malarial parasites are treated with drug containing |
| A. | penicillin |
| B. | paludrine |
| C. | aspirin |
| D. | morphine |
| Answer» C. aspirin | |
| 13. |
A broad-spectrum antibiotic such as chloramphenicol is one that |
| A. | kills both Gram positive and Gram negative bacteria |
| B. | kills all bacteria |
| C. | kills numerous types of microbes |
| D. | kills all microorganisms |
| Answer» D. kills all microorganisms | |
| 14. |
A chemical, used for removal of microorganisms from mucous membrane and skin, called as |
| A. | Detergents |
| B. | Alcohol |
| C. | Pesticides |
| D. | Antiseptics |
| Answer» E. | |
| 15. |
'surgical staphylococcal' wound infection is prevented by drug |
| A. | Rifampin |
| B. | Cefazolin |
| C. | Amoxicillin |
| D. | Erythromycin |
| Answer» C. Amoxicillin | |
| 16. |
The mode of action of polymyxin is to |
| A. | inhibit protein synthesis |
| B. | inhibit DNA synthesis |
| C. | injury to the plasma membrane |
| D. | inhibit folic acid synthesis |
| Answer» D. inhibit folic acid synthesis | |
| 17. |
Penicillin production is optimum in |
| A. | batch operation systems |
| B. | continuous operation systems |
| C. | discontinuous operation system |
| D. | unique operation system |
| Answer» B. continuous operation systems | |
| 18. |
To prevent from 'pathogens' first line defense mechanism is called as |
| A. | Adaptive immunity |
| B. | Innate immunity |
| C. | Resistance |
| D. | Defense |
| Answer» C. Resistance | |
| 19. |
For purification of swimming pools and water supplies of chemical used is |
| A. | Alcohol |
| B. | Chlorine |
| C. | Iodine |
| D. | Heavy metals |
| Answer» C. Iodine | |
| 20. |
Which of the following is not β-lactamase-resistant penicillin? |
| A. | Oxacillin |
| B. | Nafcillin |
| C. | Carbenicillin |
| D. | Methicillin |
| Answer» D. Methicillin | |
| 21. |
The antibiotics not having good activity against Enterobacteriaceae is |
| A. | clindamycin |
| B. | cefoxitin |
| C. | trimethoprim-sulphamethoxazole |
| D. | ciprofloxacin |
| Answer» B. cefoxitin | |
| 22. |
Drugs that are structural analogue of Para-amino benzoic acid, included |
| A. | Streptogramins |
| B. | Telithromycin |
| C. | Sulfonamides |
| D. | Linezolid |
| Answer» D. Linezolid | |
| 23. |
To produce penicillin, the main fermentable source in the culture is |
| A. | glucose |
| B. | lactose |
| C. | sulphate |
| D. | sugars |
| Answer» C. sulphate | |
| 24. |
Capability of an organism to resist a particular toxin or disease by action of defense mechanism is called |
| A. | Resistance |
| B. | Immunity |
| C. | Ability |
| D. | Defense |
| Answer» C. Ability | |
| 25. |
Which of the following may cause resistance to penicillin? |
| A. | Impermeability of cell envelope |
| B. | Production of β-lactamases by bacteria |
| C. | Alteration or lack of penicillin-binding proteins |
| D. | All of the above |
| Answer» E. | |
| 26. |
Amphotericin B and polymyxin interfere with |
| A. | cell wall synthesis |
| B. | protein synthesis |
| C. | cell membrane function |
| D. | DNA function |
| Answer» D. DNA function | |
| 27. |
Competition of Para-aminobenzoic acid and sulfonamides, occupying active sites of enzyme, known as |
| A. | Dihydropteroate synthetase |
| B. | Transferase |
| C. | Lipase |
| D. | Peptidase |
| Answer» B. Transferase | |
| 28. |
Monobactams have tremendous activity against gram-negative rods, included |
| A. | Bacillus |
| B. | Diplobacillus |
| C. | Pseudomonas |
| D. | Streptomyces |
| Answer» D. Streptomyces | |
| 29. |
Drugs useful against bacteria resistant to penicillin include |
| A. | Cephalosporin only |
| B. | Erythromycins only |
| C. | Augmentin |
| D. | Cephalosporin and Erythromycins |
| Answer» E. | |
| 30. |
In order to combat virus-produced diseases, |
| A. | antibiotics shall be administered |
| B. | depressant drugs shall be administered |
| C. | amphetamines shall be administered |
| D. | body's own immunity system shall combat |
| Answer» E. | |
| 31. |
Mycoplasma and Legionella are causative agents for 'pneumonia' that is treated by |
| A. | Streptomycin |
| B. | Erythromycin |
| C. | Clindamycin |
| D. | Amikacin |
| Answer» C. Clindamycin | |
| 32. |
'Vancomycin' is effective against |
| A. | Gram negative bacteria |
| B. | Gram positive bacteria |
| C. | Gram negative rods |
| D. | Gram positive rods |
| Answer» C. Gram negative rods | |
| 33. |
Both penicillin and fluoroquinolones |
| A. | bind to and inactivate a bacterial protein |
| B. | inhibit the cross-linking of peptidoglycan |
| C. | are inactivated by β-lactamase |
| D. | must be transported into the cytoplasm in order to act |
| Answer» B. inhibit the cross-linking of peptidoglycan | |
| 34. |
Polyene antibiotics are |
| A. | large ring structures |
| B. | β-lactam - thiazolidine ring |
| C. | small ring structures |
| D. | any of these |
| Answer» B. β-lactam - thiazolidine ring | |
| 35. |
Bond between 50s ribosomal subunit and chloramphenicol, during inhibition of protein synthesis is at active site of enzyme, named as |
| A. | Peptidase |
| B. | Transferase |
| C. | Amylase |
| D. | Lipase |
| Answer» C. Amylase | |
| 36. |
The compound(s) which act(s) as metabolic antagonist is/are |
| A. | trimethoprim |
| B. | sulphonamides |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 37. |
Most 'cephalosporin' are products derived from molds of genus |
| A. | Streptomyces |
| B. | Cephalosporium |
| C. | Actinomycetes |
| D. | Algae |
| Answer» C. Actinomycetes | |
| 38. |
A ? lactam drug , having same mechanism of action as penicillin, known as |
| A. | Cephalosporin |
| B. | Carbapenems |
| C. | Monobactams |
| D. | Vancomycin |
| Answer» B. Carbapenems | |
| 39. |
The susceptibility of a microorganism to antibiotics and other chemotherapeutic agents can be determined by using |
| A. | tube dilution technique |
| B. | paper disk plate |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» D. none of these | |
| 40. |
Which of the following is not an example of potent antitumer agents? |
| A. | Anthramycin |
| B. | Sibromycin |
| C. | Neothramycin |
| D. | Erythromycin |
| Answer» E. | |
| 41. |
Passage of 'antibodies' from one person to another is called |
| A. | Passive immunity |
| B. | Active immunity |
| C. | Innate immunity |
| D. | Defense |
| Answer» B. Active immunity | |
| 42. |
During 'pasteurization' milk is heated for 30 minutes at |
| A. | 67°C |
| B. | 63°C |
| C. | 62°C |
| D. | 61°C |
| Answer» E. | |
| 43. |
'Egrosterol' synthesis is terminated by an antifungal drug, called as |
| A. | Nystatin |
| B. | Amphotericin B |
| C. | Azoles |
| D. | Flucytosine |
| Answer» D. Flucytosine | |
| 44. |
A drug that is approved by government, in treating a particular disease, is called |
| A. | Drug therapy |
| B. | Chemotherapy |
| C. | First line drug |
| D. | Second line drug |
| Answer» D. Second line drug | |
| 45. |
Before ' immunization' skin is cleaned with |
| A. | Detergents |
| B. | Insecticides |
| C. | Alcohol |
| D. | Ethanol |
| Answer» E. | |
| 46. |
Method used for sterilization of solutions is called |
| A. | Sterilization |
| B. | Autoclaving |
| C. | Filtration |
| D. | Radiations |
| Answer» D. Radiations | |
| 47. |
A parenteral route of drug administration refers to |
| A. | oral |
| B. | nonoral |
| C. | intravenously |
| D. | intramuscularly |
| Answer» C. intravenously | |
| 48. |
Which of the following drugs may show plasmid-mediated resistance? |
| A. | Nalidixic acid |
| B. | Ampicillin |
| C. | Rifampicin |
| D. | Methicillin |
| Answer» C. Rifampicin | |
| 49. |
Vancomycin inhibits peptidoglycan synthesis by binding |
| A. | D-alanyl - D-alanine |
| B. | alanine racemase |
| C. | D-alanyl - D-alanine synthetase |
| D. | amidase |
| Answer» B. alanine racemase | |
| 50. |
Most antibiotics are isolated from |
| A. | viruses |
| B. | aquatic microorganisms |
| C. | soil microorganisms |
| D. | plants |
| Answer» D. plants | |