MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
DNA is microinfected into the fertilized egg |
| A. | after the fusion of male and female nuclei |
| B. | before the fusion of male and female nuclei |
| C. | at the time of fusion of male and female nuclei |
| D. | any time, it can be infected |
| Answer» C. at the time of fusion of male and female nuclei | |
| 2. |
What is the concentration of CO2 required for culturing animal cells? |
| A. | 2-5% |
| B. | 1-10% |
| C. | 10-15% |
| D. | 15-20% |
| Answer» C. 10-15% | |
| 3. |
Transfection refers to which of the following? |
| A. | Synthesis of mRNA from DNA template |
| B. | Synthesis of protein based on mRNA sequence |
| C. | Introduction of foreign gene in to a cell |
| D. | The process by which a cell become malignant |
| Answer» D. The process by which a cell become malignant | |
| 4. |
Retroviruses consist of |
| A. | Ds DNA genome |
| B. | Ss DNA genome |
| C. | RNA genome |
| D. | cDNA genome |
| Answer» D. cDNA genome | |
| 5. |
An established cell line can be called where it has been subcultured at least |
| A. | 70 times at an interval of 3 days between subcultures |
| B. | 40 times at an interval of 3 days between subcultures |
| C. | 70 times at an interval of 1 day between subcultures |
| D. | 50 times at an interval of 3 days between subcultures |
| Answer» B. 40 times at an interval of 3 days between subcultures | |
| 6. |
Superovulation is an |
| A. | increased ovulatory response by external hormonal therapy |
| B. | decreased ovulatory response by external hormonal therapy |
| C. | decreased ovulatory response by internal hormonal therapy |
| D. | increased ovulatory response by internal hormonal therapy |
| Answer» B. decreased ovulatory response by external hormonal therapy | |
| 7. |
During the growth of animal cells in culture, it is noticed that the cells do not look very healthy. After an investigation, this is found that there is a lot of lactic acid in the culture fluid. What is probably wrong with this culture? |
| A. | Ethyl alcohol is being produced in excess |
| B. | The cells have too much oxygen |
| C. | Glycolysis is being inhibited |
| D. | The cells do not have enough oxygen |
| Answer» E. | |
| 8. |
Which of the following is not a source of energy in active muscle cells? |
| A. | Creatine phosphate |
| B. | ATP |
| C. | Lactic acid |
| D. | Glucose |
| Answer» D. Glucose | |
| 9. |
The nucleous of mature unfertilized ovum may be removed by |
| A. | irradiation |
| B. | surgery |
| C. | both (a) and (b) |
| D. | neutralization and homogenization |
| Answer» D. neutralization and homogenization | |
| 10. |
How many chromosomes are there in Caernorhabditis elegans? |
| A. | 3 |
| B. | 6 |
| C. | 9 |
| D. | 12 |
| Answer» C. 9 | |
| 11. |
If two genes show 50% recombination |
| A. | they are on different chromosomes |
| B. | they are on same chromosome but far apart |
| C. | both (a) and (b) |
| D. | they are closely located on the same chromosome |
| Answer» D. they are closely located on the same chromosome | |
| 12. |
Which of the following denotes a pair of contrasting characters? |
| A. | Alleles |
| B. | Phenotype |
| C. | Homozygous |
| D. | Genotype |
| Answer» B. Phenotype | |
| 13. |
When a fertilized egg cell develops into an embryo, the entropy of the living system |
| A. | decreases |
| B. | increases |
| C. | remains constant |
| D. | none of these |
| Answer» B. increases | |
| 14. |
Using bovine papilloma virus (BPV) derived vectors, permanent cell lines can be obtained carrying a recombinant DNA |
| A. | episomally only |
| B. | integrated only |
| C. | either episomally or integrated at high copy number |
| D. | either episomally or integrated at low copy number |
| Answer» D. either episomally or integrated at low copy number | |
| 15. |
Which of the followings are the metabolic products of glucose and glutamine? |
| A. | CO2 and NH3 |
| B. | CO2 and lactate |
| C. | Lactate and ammonium |
| D. | Lactate only |
| Answer» D. Lactate only | |
| 16. |
The degree or extent to which a given genotype is expressed phenotypically in a particular individual is defined as |
| A. | penetrance |
| B. | expressivity |
| C. | inheritance strength |
| D. | environmental influence |
| Answer» C. inheritance strength | |
| 17. |
DNA microinjection into the egg has been used to produce which of the following transgenic animals? |
| A. | Mice |
| B. | Chicken |
| C. | Pigs |
| D. | All of these |
| Answer» E. | |
| 18. |
Accumulation of lactate leads to |
| A. | increase in pH |
| B. | no change in pH |
| C. | reduction in the pH of culture hence loss of cell viability |
| D. | no loss of cell viability |
| Answer» D. no loss of cell viability | |
| 19. |
The technique, mainly used for the diagnosing birth defects in the fetus by means of needle, is called |
| A. | amniocentesis |
| B. | ectogensis |
| C. | transplantation |
| D. | all of the above |
| Answer» B. ectogensis | |
| 20. |
DNA into fish is injected into |
| A. | pronuclei |
| B. | cytoplasm |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» C. both (a) and (b) | |
| 21. |
Genetic change can occur only in |
| A. | one way |
| B. | two ways |
| C. | three ways |
| D. | four ways |
| Answer» E. | |
| 22. |
Incase of inversion when the inverted segment of chromosome includes centromere, it is known as |
| A. | paracentric inversion |
| B. | double inversion |
| C. | inverted inversion |
| D. | pericentric inversion |
| Answer» E. | |
| 23. |
Which part of a cell carries the information that is passed from one generation to the next? |
| A. | Cell |
| B. | Nucleus |
| C. | Cytoplasm |
| D. | Chloroplast |
| Answer» C. Cytoplasm | |
| 24. |
What is the effect of excess accumulation of metabolite products (lactate and ammonium) on cells? |
| A. | They act as growth promoters |
| B. | They act as growth inhibitors |
| C. | Have no effect on cells |
| D. | Lactate helps in the growth while ammonium inhibits the growth |
| Answer» E. | |
| 25. |
Which of the following statements best describes a clone? |
| A. | An artificial life form |
| B. | An offspring where all of the genetic material in every cell is identical to that of both parents |
| C. | An offspring where all of the genetic material in every cell is identical to that of one of its parents |
| D. | A type of sheep |
| Answer» D. A type of sheep | |
| 26. |
Which of the following promoters is repressed in presence of glucose? |
| A. | Galactokinase (GAL 1) |
| B. | Acid phosphatase (PHOS) |
| C. | Both (a) and (b) |
| D. | Phosphoglycerate kinase (PGK) |
| Answer» B. Acid phosphatase (PHOS) | |
| 27. |
5-fluoro orotic acid inhibits the growth if one of the following marker is present in the yeast. That is |
| A. | His 3 |
| B. | Lys 2 |
| C. | Ura 3 |
| D. | Trp 1 |
| Answer» D. Trp 1 | |
| 28. |
Bovine papilloma virus has a circular double stranded DNA genome of about |
| A. | 2.5 kb |
| B. | 5.2 kb |
| C. | 7.9 kb |
| D. | 9.5 kb |
| Answer» D. 9.5 kb | |
| 29. |
Which of the following can be used for reducing the size of gene inserts containing introns? |
| A. | Vaccinia virus |
| B. | Baculo virus |
| C. | Retro virus |
| D. | none of these |
| Answer» D. none of these | |
| 30. |
A map of chromosomes that utilizes cloned and sequenced DNA fragments rather than genetic markers is known as |
| A. | a physical map |
| B. | a genetic map |
| C. | a cloning map |
| D. | none of these |
| Answer» B. a genetic map | |
| 31. |
Lytic infection of SV 40 does not occur in |
| A. | permissive cells |
| B. | non permissive cells |
| C. | both (a) and (b) |
| D. | none of these |
| Answer» C. both (a) and (b) | |
| 32. |
Which one of the following is true about Yeast Integrative plasmids (YIp) vectors? |
| A. | Allows transformation by using crossing over |
| B. | Has a origin of replication and rep genes |
| C. | Carries autonomously replicating sequence |
| D. | Carries centromere and telomere sequences |
| Answer» B. Has a origin of replication and rep genes | |
| 33. |
SV 40 vectors, in which early region replacements are carried out, require |
| A. | COS cell line |
| B. | SV 40 helper virus |
| C. | pBR 322 vector |
| D. | none of these |
| Answer» B. SV 40 helper virus | |
| 34. |
How does dosage compensation in Drosophila occur? |
| A. | Hypertranscription of male X chromosome |
| B. | Hypotranscription of female X chromosome |
| C. | X inactivation in females |
| D. | Chimerism |
| Answer» B. Hypotranscription of female X chromosome | |
| 35. |
A diagram depicting chromosomes of haploid set of an organism ordered in a series of decreasing size is known as |
| A. | zymogram |
| B. | chromogram |
| C. | idiogram |
| D. | karyogram |
| Answer» D. karyogram | |
| 36. |
Hairy wing character of Drosophila is due to |
| A. | duplication in region of chromosome |
| B. | deletion in region of chromosome |
| C. | due to presence of additional X-chromosome |
| D. | due to a point mutation |
| Answer» B. deletion in region of chromosome | |
| 37. |
A cross shaped (+) or a ring involving four chromosomes may be formed during metaphase I in case of |
| A. | translocation heterozygote |
| B. | deficiency |
| C. | haploid organism |
| D. | duplication |
| Answer» B. deficiency | |
| 38. |
Transmission of a gene from male parent to female child to male grand child is known as |
| A. | holandric inheritance |
| B. | quantitative inheritance |
| C. | criss-cross inheritance |
| D. | maternal inheritance |
| Answer» D. maternal inheritance | |
| 39. |
Bar eye character of Drosophila is due to |
| A. | duplication in region of 16A of X chromosome |
| B. | deletion in region of 16A of X chromosome |
| C. | due to presence of additional X-chromosome |
| D. | due to a point mutation in eye-locus |
| Answer» B. deletion in region of 16A of X chromosome | |
| 40. |
An odd number of cross overs in inverted region will result into formation of a dicentric chromatid and acentric chromatid at anaphase I incase of |
| A. | pericentric inversion |
| B. | paracentric inversion |
| C. | double inversion |
| D. | none of these |
| Answer» C. double inversion | |
| 41. |
The percentage of individual with a given genotype, which exhibits the associated phenotype, is defined as |
| A. | penetrance |
| B. | expressivity |
| C. | inheritance percent |
| D. | environmental influence |
| Answer» B. expressivity | |
| 42. |
Diethyl stilbestrol (DES), a synthetic estrogen causes |
| A. | chromosome lagging |
| B. | disruption of mitotic spindle |
| C. | centriole elongation |
| D. | all of the above |
| Answer» E. | |
| 43. |
Cloning genes in the yeast offer which of following advantage(s)? |
| A. | Over production of proteins of commercial value |
| B. | Ability to glycosylate proteins during secretion |
| C. | Ability to clone large piece of DNA |
| D. | All of the above |
| Answer» E. | |
| 44. |
The size of the genome of SV 40 is |
| A. | 7.2 kb |
| B. | 69 kb |
| C. | 5.2 kb |
| D. | 110 kb |
| Answer» D. 110 kb | |
| 45. |
Which one of the following is true about Yeast Centromeric plasmids (YCp) vectors? |
| A. | Contains centromeric sequences |
| B. | Segregates during meiosis and mitosis |
| C. | Functions as true chromosome |
| D. | All of the above |
| Answer» E. | |
| 46. |
Which one of the following is true about Yeast Episomal plasmids (YEp) vectors? |
| A. | Allows transformation by using crossing over |
| B. | Has a origin of replication and rep genes |
| C. | Carries autonomously replicating sequence |
| D. | Carries centromere and telomere sequences |
| Answer» C. Carries autonomously replicating sequence | |
| 47. |
α-aminoadipate inhibits the growth if one of the following marker is present in the yeast. That is |
| A. | His 3 |
| B. | Lys 2 |
| C. | Ura 3 |
| D. | Trp 1 |
| Answer» C. Ura 3 | |
| 48. |
In case of Baculoviruses, the foreign gene |
| A. | is inserted downstream of polyhedrin promoter |
| B. | is inserted downstream of viral origin of replication |
| C. | is inserted between the polyhedrin promoter and downstream sequences |
| D. | is inserted randomly in viral genome |
| Answer» D. is inserted randomly in viral genome | |
| 49. |
Polyhedrin protein is |
| A. | non essential for baculo virus replication |
| B. | major component of protein matrix in which viruses are embedded |
| C. | both (a) and (b) |
| D. | essential for baculo virus replication |
| Answer» D. essential for baculo virus replication | |
| 50. |
Which of the following histone is not present in SV40 virus? |
| A. | H1 |
| B. | H2A |
| C. | H3 |
| D. | H4 |
| Answer» B. H2A | |