MCQOPTIONS
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MCQOPTIONS
This section includes 657 Mcqs, each offering curated multiple-choice questions to sharpen your Testing Subject knowledge and support exam preparation. Choose a topic below to get started.
| 1. |
Which of the following gene have been introduced into the transgenic fish? |
| A. | Human or rat gene for growth hormone |
| B. | Chicken gene for delta crystalline protein |
| C. | E. coli gene for β-galactosidase |
| D. | All of the above |
| Answer» E. | |
| 2. |
Yeast episomal plasmids (YEp) were constructed using |
| A. | 2μm yeast plasmid, fragments of yeast nuclear DNA and E coli vector pMB 9 |
| B. | 2μm yeast plasmid, fragments of yeast nuclear DNA and E coli vector pBR 322 |
| C. | 12μm yeast plasmid and E coli vector pMB 9 |
| D. | 12μm yeast plasmid and E coli vector pBR 322 |
| Answer» B. 2μm yeast plasmid, fragments of yeast nuclear DNA and E coli vector pBR 322 | |
| 3. |
Maximum insert size in case of adenovirus vectors is |
| A. | 6-8 kb |
| B. | 4-6 kb |
| C. | 10-12 kb |
| D. | 20 kb |
| Answer» B. 4-6 kb | |
| 4. |
YAC vectors can be used to obtain artificial chromosomes because it carries |
| A. | centromere |
| B. | telomere |
| C. | autonomously replicating sequence |
| D. | all of these |
| Answer» E. | |
| 5. |
Which of the following(s) is/are the most commonly used markers in yeast? |
| A. | His 3 |
| B. | Ura 3 |
| C. | Trp 1 |
| D. | All of these |
| Answer» E. | |
| 6. |
Range of osmolarity tolerated/accepted in mOsm/Kg of H2O by mammalian cells is |
| A. | 150-300 |
| B. | 280-360 |
| C. | 300-325 |
| D. | 360-400 |
| Answer» C. 300-325 | |
| 7. |
Moloney-Mu-leukemia virus is an example of |
| A. | Vaccinia virus |
| B. | Baculo virus |
| C. | Retro virus |
| D. | none of these |
| Answer» D. none of these | |
| 8. |
Which of the following is the process of choosing parent organisms for the characteristics that is wanted in their offspring? |
| A. | Active selection |
| B. | Reproductive selection |
| C. | Selective breeding |
| D. | Breeding selection |
| Answer» D. Breeding selection | |
| 9. |
To prevent the accumulation of lactate |
| A. | low glutamine concentration is required |
| B. | high glutamine concentration is required |
| C. | low glucose concentration is required |
| D. | high glucose concentration is required |
| Answer» D. high glucose concentration is required | |
| 10. |
The success of embryo transplantation depends upon the ability to obtain an increased number of embryos from animals of superior genetic merit, which can be achieved by the use of |
| A. | exogenous gonadatrophic hormones |
| B. | endogenous gonadatrophic hormones |
| C. | both (a) and (b) |
| D. | FSH (Follicle Stimulating Hormone) |
| Answer» B. endogenous gonadatrophic hormones | |
| 11. |
In animal cell culture, particularly mammalian cell culture, transformation means |
| A. | uptake of new genetic material |
| B. | phenotypic modifications of cells in culture |
| C. | both (a) and (b) |
| D. | release of genetic information |
| Answer» C. both (a) and (b) | |
| 12. |
Disaggregating of cells can be achieved by |
| A. | physical disruption |
| B. | enzymatic digestion |
| C. | treating with chelating agents |
| D. | all of the above |
| Answer» E. | |
| 13. |
Exchange of segments between non homologous chromosomes is best known as |
| A. | translation |
| B. | translocation |
| C. | recombination |
| D. | crossing over |
| Answer» C. recombination | |
| 14. |
Multiple ovulation and embryo transfer (MOET) |
| A. | can increase the rate of progress in dairy cattle |
| B. | allows progeny testing of males |
| C. | allows progeny testing of females |
| D. | all of the above |
| Answer» E. | |
| 15. |
SV 40 vectors, in which late region replacements are done, require |
| A. | COS cell line |
| B. | SV 40 helper virus |
| C. | pBR 322 vector |
| D. | none of these |
| Answer» C. pBR 322 vector | |
| 16. |
When dissolved oxygen is lower than the critical concentration, viable cell concentration declines because of |
| A. | incomplete glutamine oxidation |
| B. | increase in specific lactate production from glucose |
| C. | both (a) and (b) |
| D. | accumulation of ammonia |
| Answer» D. accumulation of ammonia | |
| 17. |
Yeast Replicating plasmids (YRp) carry |
| A. | centromere |
| B. | telomere |
| C. | autonomously replicating sequence |
| D. | both (a) and (c) |
| Answer» D. both (a) and (c) | |
| 18. |
Which of the following is the technique used for the embryo culture? |
| A. | Organ cultures on plasma clots |
| B. | Organ cultures on agar |
| C. | Whole embryo cultures |
| D. | All of these |
| Answer» E. | |
| 19. |
Autographa California nuclear polyhedrosis virus that is used as a vector for animal cells is an example of |
| A. | Vaccinia virus |
| B. | Baculo virus |
| C. | Papilloma virus |
| D. | Retrovirus |
| Answer» C. Papilloma virus | |
| 20. |
Recombinant SV40 viruses introduce the foreign DNA into cells |
| A. | with the DNA mediated transfection |
| B. | without the DNA mediated transfection |
| C. | with the RNA mediated transfection |
| D. | without the RNA mediated transfection |
| Answer» C. with the RNA mediated transfection | |
| 21. |
Higher dissolved oxygen concentration in the culture media are toxic and lead to |
| A. | DNA degradation |
| B. | lipid peroxidation |
| C. | metabolism of nutrients in culture media at a rate greater than that required for consumption |
| D. | all of the above |
| Answer» E. | |
| 22. |
Cos cell line is |
| A. | cohesive end site of phage λ |
| B. | derivative of permissive CV-1 monkey cell line |
| C. | cohesive initial site of phage λ |
| D. | derivative of non-permissive CV-1 monkey cell line |
| Answer» C. cohesive initial site of phage λ | |
| 23. |
Autonomously replicating sequence is not present in |
| A. | YIp |
| B. | YRp |
| C. | YCp |
| D. | YAC |
| Answer» B. YRp | |
| 24. |
Which of the following is correct when a character shows continuous variation assuming a normal distribution? |
| A. | It is governed by many genes with small cumulative effect |
| B. | It is not controlled genetically |
| C. | Many of the variation is due to fluctuation of climate |
| D. | None of the above |
| Answer» B. It is not controlled genetically | |
| 25. |
How many chromosomes are there in the budding yeast (S. cerevisiae)? |
| A. | 16 |
| B. | 17 |
| C. | 18 |
| D. | 20 |
| Answer» B. 17 | |
| 26. |
Raphanobrassica is a classical example of |
| A. | aneuploidy |
| B. | nullisomy |
| C. | allopolyploidy |
| D. | None of the above |
| Answer» D. None of the above | |
| 27. |
In a dihybrid cross, the progeny of an Fl individual (hetero2ygous for both characters) will show a phenotypic ratio of |
| A. | 1:1:1:1 |
| B. | 1:2:2:1 |
| C. | 9:3:3:1 |
| D. | 3:1:1:3 |
| Answer» B. 1:2:2:1 | |
| 28. |
In an organism, the chromosome number is maintained constant because of |
| A. | independent assortment |
| B. | crossing over |
| C. | DNA duplication |
| D. | synapsis |
| Answer» D. synapsis | |
| 29. |
WHICH_OF_THE_FOLLOWING_IS_NOT_THE_MAJOR_FUNCTION_OF_THE_SERUM??$ |
| A. | Promotion of tuber and bulb formation |
| B. | Stimulate cell growth |
| C. | Enhance cell attachment |
| D. | Provide transport proteins |
| Answer» B. Stimulate cell growth | |
| 30. |
Which of the following is NOT the part of growth medium for animal culture? |
| A. | Starch |
| B. | Serum |
| C. | Carbon source |
| D. | Inorganic salts |
| Answer» B. Serum | |
| 31. |
Name the cell line of the human embryonic lung? |
| A. | HeLa |
| B. | WISH |
| C. | L |
| D. | MRC-5 |
| Answer» E. | |
| 32. |
Which of the following is the characteristics of a normal cell? |
| A. | Anchorage independent |
| B. | Continuous cell lines |
| C. | Dependent on external growth factor |
| D. | No contact inhibition |
| Answer» D. No contact inhibition | |
| 33. |
Name the organism on which first cell line was observed? |
| A. | E.coli |
| B. | Sheep |
| C. | Mouse |
| D. | Drosophila |
| Answer» D. Drosophila | |
| 34. |
What is a cell line? |
| A. | Multilayer culture |
| B. | Transformed cells |
| C. | Multiple growth of cells |
| D. | Sub culturing of primary culture |
| Answer» E. | |
| 35. |
Name the type of culture which is prepared by inoculating directly from the tissue of an organism to culture media? |
| A. | Primary cell culture |
| B. | Secondary cell culture |
| C. | Cell lines |
| D. | Transformed cell culture |
| Answer» B. Secondary cell culture | |
| 36. |
Cells from kidney tissues cannot survive independently, it requires other surface for attachment and survival. |
| A. | True |
| B. | False |
| Answer» B. False | |
| 37. |
The growth of animal cells in vitro in a suitable culture medium is called___________ |
| A. | Gene expression |
| B. | Transgenesis |
| C. | Plant tissue culture |
| D. | Animal cell culture |
| Answer» E. | |