Explore topic-wise MCQs in Biochemistry.

This section includes 8 Mcqs, each offering curated multiple-choice questions to sharpen your Biochemistry knowledge and support exam preparation. Choose a topic below to get started.

1.

The Hill coefficient (n) for myoglobin and hemoglobin are respectively

A. 2.8 and 1.0
B. 1.0 and 2.8
C. 1.2 and 4.5
D. 4.5 and 1.2
Answer» C. 1.2 and 4.5
Discussion
2.

The conformational changes from the T to the R state is initiated by
A. binding of oxygen to the heme
B. movement of the proximal histidine towards the heme
C. movement of the F-helix, which contains the proximal His
D. reorganization of protein-protein contacts between the individual subunits
Answer» B. movement of the proximal histidine towards the heme
Discussion
3.

The Hill coefficient (nH) for myoglobin and hemoglobin are respectively
A. 2.8 and 1.0
B. 1.0 and 2.8
C. 1.2 and 4.5
D. 4.5 and 1.2
Answer» C. 1.2 and 4.5
Discussion
4.

The specificity of a ligand binding site on a protein is based on
A. the absence of competing ligands
B. the amino acid residues lining the binding site
C. the presence of hydrating water molecules
D. the opposite chirality of the binding ligand
Answer» C. the presence of hydrating water molecules
Discussion
5.

A protein that binds two ligands in a non-cooperative manner will show
A. a sigmodial binding curve
B. a hyperbolic binding curve
C. a linear Scatchard Plot
D. both (b) and (c)
Answer» E.
Discussion
6.

When protein binds two ligands in a non-cooperative manner, then the x-intercept of the Scatchard Plot is
A. 1
B. 2
C. not defined
D. none of the above
Answer» C. not defined
Discussion
7.

An allosteric activator
A. increases the binding affinity
B. decreases the binding affinity
C. stabilizes the R state of the protein
D. both (a) and (c)
Answer» E.
Discussion
8.

Bisphosphoglycerate (BPG) cannot bind to the oxygenated R state of hemoglobin because
A. it is displaced from the heme by oxygen
B. it is displaced from the heme by movement of the proximal histidine
C. its binding pocket becomes too small to accommodate BPG
D. BPG binds to the R state with the same affinity as the T state
Answer» D. BPG binds to the R state with the same affinity as the T state
Discussion