 
			 
			MCQOPTIONS
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				This section includes 15 Mcqs, each offering curated multiple-choice questions to sharpen your Molecular Biology knowledge and support exam preparation. Choose a topic below to get started.
| 1. | Attenuator in the tryptophan operon is the __________ | 
| A. | Operator sequence | 
| B. | Non-transcribed region within the operon | 
| C. | Leader sequence for the site of RNA polymerase binding | 
| D. | Leader sequence in the tryptophan mRNA coding for many tryptophan residues | 
| Answer» E. | |
| 2. | Which of the following is false about bacterial tryptophan operon? | 
| A. | It has two kinds of regulation system | 
| B. | The co-repressor is the catabolite activator protein | 
| C. | When tryptophan supply is insufficient the tryptophan operon activates | 
| D. | The complex of repressor with co-repressor on binding to the operator blocks transcription | 
| Answer» C. When tryptophan supply is insufficient the tryptophan operon activates | |
| 3. | In the case of lac operon, the gene expression is inhibited by __________ | 
| A. | Presence of lactose | 
| B. | Interaction of repressor with lactose | 
| C. | Interaction of repressor with operator | 
| D. | Interaction of lactose with operator | 
| Answer» D. Interaction of lactose with operator | |
| 4. | Mutation in the regulatory gene of a positively controlled operon can be identified by __________ | 
| A. | Operon induction | 
| B. | Operon repression | 
| C. | High expression | 
| D. | Constitutive expression | 
| Answer» C. High expression | |
| 5. | What effect would a loss-of-function mutation have on the expression of the gene encoding the catabolite activator protein of the lac operon? | 
| A. | Low expression in the presence of lactose and off in its absence, regardless of the presence or absence of glucose | 
| B. | High expression in the presence of lactose and off in its absence, regardless of the presence or absence of glucose | 
| C. | Low expression in the presence of glucose and off in its absence, regardless of the presence or absence of lactose | 
| D. | High expression in the presence of glucose and off in its absence, regardless of the presence or absence of lactose | 
| Answer» B. High expression in the presence of lactose and off in its absence, regardless of the presence or absence of glucose | |
| 6. | The complete expression of the lac operon requires __________ | 
| A. | Lactose | 
| B. | Allolactose | 
| C. | Lactose and cAMP | 
| D. | Allolactose and cAMP | 
| Answer» E. | |
| 7. | If there is an insertion mutation in the operator of the lac operon, the expression of the lac structural gene will be __________ | 
| A. | Resistant to catabolic expression | 
| B. | Unexpressed | 
| C. | Constitutively expressed | 
| D. | Permanently disabled | 
| Answer» D. Permanently disabled | |
| 8. | According to the repressor of lac operon which of the following are false? | 
| A. | It is the gene product of the regulatory gene | 
| B. | It binds to the promoter region | 
| C. | It blocks the transcription of structural genes | 
| D. | It combines with allolactose and thus does not bind to the operon | 
| Answer» C. It blocks the transcription of structural genes | |
| 9. | Lac operon follows a trans-acting control mechanism. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 10. | If the lac operon of the genome of bacteria is always active it has a defect in which region of the operon? | 
| A. | i | 
| B. | o | 
| C. | Promoter | 
| D. | Structural gene | 
| Answer» B. o | |
| 11. | Defects in which regions can affect the activity of the lac operon? | 
| A. | Promoter | 
| B. | i | 
| C. | Terminator | 
| D. | i and o | 
| Answer» E. | |
| 12. | How many enzymes are produced in the lac operon under the same promoter? | 
| A. | 4 | 
| B. | 3 | 
| C. | 2 | 
| D. | 1 | 
| Answer» C. 2 | |
| 13. | Presence of lactose itself induces the production of -galactoside transferase. | 
| A. | True | 
| B. | False | 
| Answer» B. False | |
| 14. | The investigation of the lac operon for the metabolism of lactose was done by __________ | 
| A. | Gilbert | 
| B. | Walter Gilbert | 
| C. | Francois Jacob and Jacques Monod | 
| D. | Walter | 
| Answer» D. Walter | |
| 15. | The functional unit in which genes are arranged consecutively is known as ___________ | 
| A. | Induction system | 
| B. | An end product repression system | 
| C. | A consecutive enzyme system | 
| D. | Operon | 
| Answer» E. | |