Home/ Questions/Q 345087
Next
In Process
Farah Kamlesh Dhillon
Asked: 2022-11-02T02:49:06+05:30 In:

Triple test performed at 15-18 weeks of pregnancy. What is the positive test result indicate that the body having down syndrome?
1. high and UE3 tend to be high that of MSAFP is low
2. MSAFP and UE3 tend to be high that of hCG is low
3. MSAFP and UE3 tend to be low that of hCG is high
4. high and UE3 tend to be high that of MSAFP is high

Triple test performed at 15-18 weeks of pregnancy. What is the positive test result indicate that the body having down syndrome?
1. high and UE3 tend to be high that of MSAFP is low
2. MSAFP and UE3 tend to be high that of hCG is low
3. MSAFP and UE3 tend to be low that of hCG is high
4. high and UE3 tend to be high that of MSAFP is high
Upsc
Leave an answer

Leave an answer

Browse

1 Answer

  1. Correct Answer – Option 3 : MSAFP and UE3 tend to be low that of hCG is high

    Explanation

    • Down’s syndrome is the commonest chromosome abnormality.
    • High maternity age is the major reason.
    • 1978-2010 incidence is increased up to 30%.

    Screening

    Second-trimester Screening Test.

    • AFP
    • E3
    • hCG

    The triple test gives 70% accuracy.

    • Inhibin A is also tested and the test is known as the quadruple test.
    • Quadruple test reliability is up to 76%. 
    Disorder MSAFP uE3 Beta hCG Inhibin A
    Open NTD Increased No change No change No change
    Down’s syndrome Decreased Decreased Increased Increased
    Trisomy 18 Decreased Decreased No change No change
    • 0