Correct Answer – Option 1 : Wernicke-Korsakoff syndrome

Concept:

About the Thiamine:

Another Name: Vitamin B1

Functions:

1. Helpful in the body’s cells i.e. it changes carbohydrates into energy.

2. Carbohydrates main work is to provide energy for the body (Majorly in the brain and nervous system).

3. Muscle contraction and conduction of nerve signals.

Important Point:

Vitamin B1 is used to treat low thiamine, diseases like beriberi, certain nerve diseases, and Wernicke-Korsakoff syndrome (WKS).

Additional Information:

• Wernicke-Korsakoff syndrome: Wernicke-Korsakoff syndrome (WKS) is a type of brain disorder caused by a lack of vitamin B-1, or thiamine.

• Symptoms:  Confusion and loss of mental activity that can progress to coma and death. Loss of muscle coordination (ataxia) that can cause leg tremor.

• Alcohol withdrawal syndrome: If someone drink alcohol heavily for a long period of time, it may have both mental and physical problems. This is called alcohol withdrawal. 

• Symptoms: headaches, nausea, tremors, anxiety, hallucinations and seizures

• Alcoholic dementia: It is a form of dementia related to the excessive drinking of alcohol. This affects memory, learning and other mental functions

• Symptoms: Effect on brain cells, resulting in poor judgment, difficulty making decisions, and lack of insight

• Huntington’s disease: Huntington’s disease is a progressive brain disorder caused by a single defective gene on chromosome 4

·        Symptoms: Involuntary jerking or writhing movements (chorea), Muscle problems, such as rigidity or muscle contracture (dystonia), Slow or abnormal eye movements, Impaired gait, posture and balance, Difficulty with speech or swallowing.