In an in vitro translation experiment, poly (UC) RNA template produced poly (Ser-Leu), while poly (AG) RNA template produced poly (Arg-Glu) polypeptide. Which one of the following options represents correct interpretations of the codons assignments for Ser, Leu, Arg and Glu?
(a) Ser-UCU, Leu-CUC, Arg-AGA, Glu-GAG
(b) Ser-CUC, Leu-GAG, Arg-UCU, Glu-AGA
(c) Ser-AGA, Leu-UCU, Arg-GAG, Glu-CUC
(d) Ser-GAG, Leu-AGA, Arg-CUC, Glu-UCU
Answer is : (a) Ser-UCU, Leu-CUC, Arg-AGA, Glu-GAG
Serine is coded by UCU, UCC, UCA, UCG, AGU, AGC
Leucine is coded by CUU, CUC, CUA, CUG, UUA, UUG
Arginine is coded by AGA, AGG, CGU, CGC, CGA, CGG
Glutamic acid is coded by GAA, GAG
Therefore, option (a) is the correct interpretation of the assigned amino acids.
Ser-UCU, Leu-CUC, Arg-AGA, Glu-GAG