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Children suffering from phenylketonuria are given food low in phenylalanine and supplemented with tyrosine. This is because they
(a) are unable to utilise phenylalanine
(b) do not require phenylalanine
(c) have increased tyrosine anabolism
(d) have increased tyrosine catabolism
Children suffering from phenylketonuria are given food low in phenylalanine and supplemented with tyrosine. This is because they
(a) are unable to utilise phenylalanine
(b) do not require phenylalanine
(c) have increased tyrosine anabolism
(d) have increased tyrosine catabolism
Answer is : (a) are unable to utilise phenylalanine
Phenylketonuria is an autosomal recessive disorder with mutation in gene for enzyme Phenylalanine Hydroxylase (PAH), making it non-functional.
Phenylalanine \(\overset{PAH}{\underset{x}{\rightarrow}}\) Tyrosine
Such person cannot metabolise the above reaction leading to accumulation of phenylalanine. So, are given food low in phenylalanine and supplemented with tyrosine.