Which of the following treatment outcomes is associated with patients who have DCIS, according to prospective randomized trials?

In NSABP B-24, breast irradiation reduced the risk of breast cancer recurrence in all subgroups except for the patients with positive surgical margins.

In NSABP B-17, the actuarial rate of breast cancer recurrence after 12 years in patients who received surgery only was 24%.

In NSABP B-17, the actuarial rate of breast cancer recurrence after 12 years in patients who received surgery plus breast irradiation was 16%.

In EORTC 10853, the subtype of DCIS histology had no effect on patients' risk for breast cancer recurrence.

Which of the following treatment outcomes is associated with patients

1.	Which of the following treatment outcomes is associated with patients who have DCIS, according to prospective randomized trials?
A.	In NSABP B-17, the actuarial rate of breast cancer recurrence after 12 years in patients who received surgery only was 24%.
B.	In NSABP B-17, the actuarial rate of breast cancer recurrence after 12 years in patients who received surgery plus breast irradiation was 16%.
C.	In NSABP B-24, breast irradiation reduced the risk of breast cancer recurrence in all subgroups except for the patients with positive surgical margins.
D.	In EORTC 10853, the subtype of DCIS histology had no effect on patients' risk for breast cancer recurrence.
Answer» C. In NSABP B-24, breast irradiation reduced the risk of breast cancer recurrence in all subgroups except for the patients with positive surgical margins.

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