The specimen of the Mycobacterium tuberculosis should be handled with safety and caution, which of the following statement is correct regarding the laboratory diagnosis of Tuberculosis?

• A. It is one of the most common laboratory acquired infection
• B. Saliva and nasal secretions are the common specimens used for the diagnosis
• C. Acid-fast staining method is the rapid detection method for microscopy
• D. The culture media with the specimen needs the CO2 concentration of 5 to 10 %