Taxane derivatives elicit cytotoxic effects mainly by which of the fol

1.	Taxane derivatives elicit cytotoxic effects mainly by which of the following mechanisms?
A.	Stabilization of microtubules and prevention of their disassembly
B.	Intercalation into DNA and inhibition of DNA replication
C.	Inhibition of topoisomerases
D.	Inhibition of DNA repair
Answer» B. Intercalation into DNA and inhibition of DNA replication

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Taxane derivatives elicit cytotoxic effects mainly by which of the following mechanisms?

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