Select the true statement concerning atherosclerosis

• A. Congenital absence of LDL cholesterol leads to premature atherosclerosis
• B. Thoracic aorta is more likely to be involved than the abdominal
• C. Fatty streaks appear in the aortas of children as young as 1 year
• D. Fatty streaks are destined to become atherosclerotic plaques
• E. Endothelial disruption always precedes atheroma development